rs2076663

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0361 (10815/29912,GnomAD)
T=0338 (9858/29118,TOPMED)
T=0385 (1930/5008,1000G)
T=0352 (1358/3854,ALSPAC)
T=0351 (1300/3708,TWINSUK)
chr6:167974511 (GRCh38.p7) (6q27)
AD
GWASdb2
1   publication(s)
See rs on genome
106 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.167974511C>T
GRCh37.p13 chr 6NC_000006.11:g.168375191C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.737T=0.263
1000GenomesAmericanSub694C=0.640T=0.360
1000GenomesEast AsianSub1008C=0.397T=0.603
1000GenomesEuropeSub1006C=0.669T=0.331
1000GenomesGlobalStudy-wide5008C=0.615T=0.385
1000GenomesSouth AsianSub978C=0.600T=0.400
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.648T=0.352
The Genome Aggregation DatabaseAfricanSub8702C=0.714T=0.286
The Genome Aggregation DatabaseAmericanSub838C=0.630T=0.370
The Genome Aggregation DatabaseEast AsianSub1610C=0.406T=0.594
The Genome Aggregation DatabaseEuropeSub18464C=0.622T=0.377
The Genome Aggregation DatabaseGlobalStudy-wide29912C=0.638T=0.361
The Genome Aggregation DatabaseOtherSub298C=0.670T=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.661T=0.338
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.649T=0.351
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs20766630.000888alcohol dependence21314694

eQTL of rs2076663 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2076663 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6168374864168374985E067-206
chr6168417175168417229E06741984
chr6168417244168417298E06742053
chr6168364686168364758E068-10433
chr6168364888168364948E068-10243
chr6168365066168365941E068-9250
chr6168371034168371238E068-3953
chr6168375200168376142E0689
chr6168381550168382137E0686359
chr6168417175168417229E06841984
chr6168418318168418728E06843127
chr6168364289168364619E069-10572
chr6168364686168364758E069-10433
chr6168381550168382137E0696359
chr6168417175168417229E06941984
chr6168417244168417298E06942053
chr6168417359168418193E06942168
chr6168418318168418728E06943127
chr6168379841168379930E0704650
chr6168417175168417229E07041984
chr6168417244168417298E07042053
chr6168417359168418193E07042168
chr6168418318168418728E07043127
chr6168363520168363741E071-11450
chr6168363813168363863E071-11328
chr6168363918168364021E071-11170
chr6168364117168364183E071-11008
chr6168364289168364619E071-10572
chr6168364686168364758E071-10433
chr6168366024168366233E071-8958
chr6168366257168366500E071-8691
chr6168366594168366724E071-8467
chr6168366771168366845E071-8346
chr6168366910168366960E071-8231
chr6168381550168382137E0716359
chr6168417175168417229E07141984
chr6168417244168417298E07142053
chr6168325598168325692E072-49499
chr6168325694168326364E072-48827
chr6168371034168371238E072-3953
chr6168363918168364021E073-11170
chr6168364117168364183E073-11008
chr6168364289168364619E073-10572
chr6168364686168364758E073-10433
chr6168367006168367147E073-8044
chr6168367254168367304E073-7887
chr6168367375168367468E073-7723
chr6168367615168367687E073-7504
chr6168375200168376142E0739
chr6168376148168376256E073957
chr6168363277168363507E074-11684
chr6168363520168363741E074-11450
chr6168363813168363863E074-11328
chr6168363918168364021E074-11170
chr6168364117168364183E074-11008
chr6168364289168364619E074-10572
chr6168364686168364758E074-10433
chr6168364888168364948E074-10243
chr6168365066168365941E074-9250
chr6168366024168366233E074-8958
chr6168366257168366500E074-8691
chr6168366594168366724E074-8467
chr6168366771168366845E074-8346
chr6168366910168366960E074-8231
chr6168367006168367147E074-8044
chr6168367254168367304E074-7887
chr6168367375168367468E074-7723
chr6168367615168367687E074-7504
chr6168381550168382137E0746359
chr6168417175168417229E07441984
chr6168417244168417298E07442053
chr6168418318168418728E07443127
chr6168362613168362752E081-12439
chr6168363093168363218E081-11973
chr6168363277168363507E081-11684
chr6168363520168363741E081-11450
chr6168363813168363863E081-11328
chr6168363918168364021E081-11170
chr6168364117168364183E081-11008
chr6168364686168364758E081-10433
chr6168364888168364948E081-10243
chr6168365066168365941E081-9250
chr6168375036168375152E081-39
chr6168375200168376142E0819
chr6168376148168376256E081957
chr6168376299168376401E0811108
chr6168376408168376479E0811217
chr6168376564168376604E0811373
chr6168376729168376818E0811538
chr6168376821168376871E0811630
chr6168377357168377433E0812166
chr6168382420168383090E0817229
chr6168398204168398631E08123013
chr6168398742168398802E08123551
chr6168399033168399224E08123842
chr6168362204168362277E082-12914
chr6168362280168362349E082-12842
chr6168362396168362560E082-12631
chr6168362613168362752E082-12439
chr6168363093168363218E082-11973
chr6168363277168363507E082-11684
chr6168363520168363741E082-11450
chr6168363813168363863E082-11328
chr6168363918168364021E082-11170
chr6168375036168375152E082-39
chr6168375200168376142E0829