SNP Detail Info-rs2092236

Organism: Homo sapiens

Alleles: A>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0201 (6027/29934,GnomAD)
G=0270 (7863/29118,TOPMED)
G=0226 (1132/5008,1000G)
G=0051 (195/3854,ALSPAC)
G=0057 (213/3708,TWINSUK)

Position: chr6:132285899 (GRCh38.p7) (6q23.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 9 Enhancers around

Promoter: 8 Promoters around

Sequence Name	Change(s)
GRCh38.p7 chr 6	NC_000006.12:g.132285899A>G
GRCh37.p13 chr 6	NC_000006.11:g.132607038A>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.398	G=0.602
1000Genomes	American	Sub	694	A=0.910	G=0.090
1000Genomes	East Asian	Sub	1008	A=0.913	G=0.087
1000Genomes	Europe	Sub	1006	A=0.935	G=0.065
1000Genomes	Global	Study-wide	5008	A=0.774	G=0.226
1000Genomes	South Asian	Sub	978	A=0.880	G=0.120
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.949	G=0.051
The Genome Aggregation Database	African	Sub	8700	A=0.482	G=0.518
The Genome Aggregation Database	American	Sub	838	A=0.930	G=0.070
The Genome Aggregation Database	East Asian	Sub	1610	A=0.902	G=0.098
The Genome Aggregation Database	Europe	Sub	18484	A=0.930	G=0.069
The Genome Aggregation Database	Global	Study-wide	29934	A=0.798	G=0.201
The Genome Aggregation Database	Other	Sub	302	A=0.950	G=0.050
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.730	G=0.270
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.943	G=0.057

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs2092236	0.00052	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr6	132601237	132601297	E068	-5741
chr6	132619587	132619737	E069	12549
chr6	132618451	132618501	E071	11413
chr6	132601237	132601297	E072	-5741
chr6	132567323	132568074	E081	-38964
chr6	132598988	132599144	E081	-7894
chr6	132598988	132599144	E082	-7894
chr6	132610790	132610905	E082	3752
chr6	132611046	132611145	E082	4008

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr6	132600698	132601199	E067	-5839
chr6	132600698	132601199	E068	-5839
chr6	132600698	132601199	E069	-5839
chr6	132600698	132601199	E070	-5839
chr6	132600698	132601199	E071	-5839
chr6	132600698	132601199	E072	-5839
chr6	132600698	132601199	E074	-5839
chr6	132600698	132601199	E082	-5839

rs2092236