rs2101469

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0169 (5078/29968,GnomAD)
C=0136 (3968/29118,TOPMED)
C=0127 (637/5008,1000G)
C=0222 (855/3854,ALSPAC)
C=0201 (744/3708,TWINSUK)
chr11:6376106 (GRCh38.p7) (11p15.4)
AD
GWASdb2
1   publication(s)
See rs on genome
492 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 11NC_000011.10:g.6376106T>C
GRCh37.p13 chr 11NC_000011.9:g.6397336T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.918C=0.082
1000GenomesAmericanSub694T=0.840C=0.160
1000GenomesEast AsianSub1008T=0.830C=0.170
1000GenomesEuropeSub1006T=0.794C=0.206
1000GenomesGlobalStudy-wide5008T=0.873C=0.127
1000GenomesSouth AsianSub978T=0.960C=0.040
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.778C=0.222
The Genome Aggregation DatabaseAfricanSub8726T=0.901C=0.099
The Genome Aggregation DatabaseAmericanSub838T=0.880C=0.120
The Genome Aggregation DatabaseEast AsianSub1616T=0.834C=0.166
The Genome Aggregation DatabaseEuropeSub18488T=0.794C=0.205
The Genome Aggregation DatabaseGlobalStudy-wide29968T=0.830C=0.169
The Genome Aggregation DatabaseOtherSub300T=0.870C=0.130
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.863C=0.136
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.799C=0.201
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs21014690.00056alcohol dependence20201924

eQTL of rs2101469 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2101469 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1163544686354685E067-42651
chr1163547476354841E067-42495
chr1163549986355070E067-42266
chr1164130526413169E06715716
chr1164132686413357E06715932
chr1164143256414425E06716989
chr1164144756414598E06717139
chr1164148406414894E06717504
chr1164149706415068E06717634
chr1164152206415281E06717884
chr1164153176415409E06717981
chr1164154436415601E06718107
chr1164156146415670E06718278
chr1164157586415808E06718422
chr1164159006416004E06718564
chr1164161006416154E06718764
chr1164162746416392E06718938
chr1164164986416585E06719162
chr1164168506416929E06719514
chr1164170946417144E06719758
chr1164172076417257E06719871
chr1164173076417395E06719971
chr1164182866418336E06720950
chr1164183496418399E06721013
chr1164184686418789E06721132
chr1164188296419173E06721493
chr1164192726419418E06721936
chr1164195806419637E06722244
chr1164198676419944E06722531
chr1164208396420879E06723503
chr1164209886421042E06723652
chr1164219066422084E06724570
chr1164222446422400E06724908
chr1164225786423186E06725242
chr1164270466427414E06729710
chr1164276086427733E06730272
chr1164278976427974E06730561
chr1164279996428054E06730663
chr1164280676428143E06730731
chr1164282426428293E06730906
chr1164284856428535E06731149
chr1164285736428724E06731237
chr1164294496429542E06732113
chr1164311806431255E06733844
chr1164312726431312E06733936
chr1164313496431389E06734013
chr1164318716431993E06734535
chr1164324016432471E06735065
chr1164341246434221E06736788
chr1164344196434779E06737083
chr1164367116436878E06739375
chr1164370856437125E06739749
chr1164378576438015E06740521
chr1164020246402258E0684688
chr1164024086402503E0685072
chr1164025606402610E0685224
chr1164130526413169E06815716
chr1164132686413357E06815932
chr1164188296419173E06821493
chr1164219066422084E06824570
chr1164222446422400E06824908
chr1164225786423186E06825242
chr1164270466427414E06829710
chr1164276086427733E06830272
chr1164278976427974E06830561
chr1164279996428054E06830663
chr1164280676428143E06830731
chr1164282426428293E06830906
chr1164284856428535E06831149
chr1164285736428724E06831237
chr1164311806431255E06833844
chr1164312726431312E06833936
chr1164313496431389E06834013
chr1164318716431993E06834535
chr1164324016432471E06835065
chr1164330726433237E06835736
chr1164341246434221E06836788
chr1164344196434779E06837083
chr1164361436436697E06838807
chr1164367116436878E06839375
chr1164370856437125E06839749
chr1164371396437348E06839803
chr1164375266437614E06840190
chr1164377116437811E06840375
chr1164378576438015E06840521
chr1164382586438308E06840922
chr1163778686378123E069-19213
chr1163781386378929E069-18407
chr1164004036400800E0693067
chr1164011306401187E0693794
chr1164013156401384E0693979
chr1164013856401482E0694049
chr1164015886401638E0694252
chr1164017076401771E0694371
chr1164018626401949E0694526
chr1164020246402258E0694688
chr1164103826410444E06913046
chr1164104766410542E06913140
chr1164130526413169E06915716
chr1164133926413531E06916056
chr1164143256414425E06916989
chr1164144756414598E06917139
chr1164146696414719E06917333
chr1164148406414894E06917504
chr1164149706415068E06917634
chr1164152206415281E06917884
chr1164153176415409E06917981
chr1164154436415601E06918107
chr1164156146415670E06918278
chr1164157586415808E06918422
chr1164159006416004E06918564
chr1164161006416154E06918764
chr1164162746416392E06918938
chr1164164986416585E06919162
chr1164168506416929E06919514
chr1164170946417144E06919758
chr1164172076417257E06919871
chr1164173076417395E06919971
chr1164182866418336E06920950
chr1164183496418399E06921013
chr1164184686418789E06921132
chr1164188296419173E06921493
chr1164192726419418E06921936
chr1164195806419637E06922244
chr1164198676419944E06922531
chr1164206626420764E06923326
chr1164208396420879E06923503
chr1164209886421042E06923652
chr1164211236421173E06923787
chr1164213606421410E06924024
chr1164219066422084E06924570
chr1164222446422400E06924908
chr1164225786423186E06925242
chr1164270466427414E06929710
chr1164276086427733E06930272
chr1164278976427974E06930561
chr1164279996428054E06930663
chr1164280676428143E06930731
chr1164282426428293E06930906
chr1164284856428535E06931149
chr1164285736428724E06931237
chr1164303676430462E06933031
chr1164311806431255E06933844
chr1164312726431312E06933936
chr1164313496431389E06934013
chr1164344196434779E06937083
chr1164358626435916E06938526
chr1164359356436085E06938599
chr1164361436436697E06938807
chr1164367116436878E06939375
chr1164370856437125E06939749
chr1164371396437348E06939803
chr1164375266437614E06940190
chr1164377116437811E06940375
chr1164378576438015E06940521
chr1164382586438308E06940922
chr1164383636438442E06941027
chr1164415926441643E06944256
chr1164100906410210E07012754
chr1164103826410444E07013046
chr1164104766410542E07013140
chr1164130526413169E07015716
chr1164132686413357E07015932
chr1164133926413531E07016056
chr1164188296419173E07021493
chr1164192726419418E07021936
chr1164276086427733E07030272
chr1164278976427974E07030561
chr1164279996428054E07030663
chr1164280676428143E07030731
chr1164282426428293E07030906
chr1164284856428535E07031149
chr1164285736428724E07031237
chr1164341246434221E07036788
chr1164344196434779E07037083
chr1164356646435761E07038328
chr1164358626435916E07038526
chr1164359356436085E07038599
chr1164361436436697E07038807
chr1164367116436878E07039375
chr1164371396437348E07039803
chr1164375266437614E07040190
chr1164377116437811E07040375
chr1164378576438015E07040521
chr1164386016438651E07041265
chr1164387186438799E07041382
chr1164415926441643E07044256
chr1163544686354685E071-42651
chr1163547476354841E071-42495
chr1163549986355070E071-42266
chr1164004036400800E0713067
chr1164011306401187E0713794
chr1164013156401384E0713979
chr1164013856401482E0714049
chr1164015886401638E0714252
chr1164017076401771E0714371
chr1164018626401949E0714526
chr1164020246402258E0714688
chr1164024086402503E0715072
chr1164025606402610E0715224
chr1164100906410210E07112754
chr1164103826410444E07113046
chr1164104766410542E07113140
chr1164130526413169E07115716
chr1164132686413357E07115932
chr1164133926413531E07116056
chr1164143256414425E07116989
chr1164144756414598E07117139
chr1164146696414719E07117333
chr1164148406414894E07117504
chr1164149706415068E07117634
chr1164152206415281E07117884
chr1164153176415409E07117981
chr1164154436415601E07118107
chr1164156146415670E07118278
chr1164157586415808E07118422
chr1164159006416004E07118564
chr1164161006416154E07118764
chr1164162746416392E07118938
chr1164164986416585E07119162
chr1164168506416929E07119514
chr1164170946417144E07119758
chr1164172076417257E07119871
chr1164173076417395E07119971
chr1164182866418336E07120950
chr1164183496418399E07121013
chr1164184686418789E07121132
chr1164188296419173E07121493
chr1164192726419418E07121936
chr1164195806419637E07122244
chr1164213606421410E07124024
chr1164219066422084E07124570
chr1164222446422400E07124908
chr1164225786423186E07125242
chr1164270466427414E07129710
chr1164276086427733E07130272
chr1164278976427974E07130561
chr1164279996428054E07130663
chr1164280676428143E07130731
chr1164282426428293E07130906
chr1164284856428535E07131149
chr1164285736428724E07131237
chr1164293816429421E07132045
chr1164294496429542E07132113
chr1164303676430462E07133031
chr1164311806431255E07133844
chr1164312726431312E07133936
chr1164313496431389E07134013
chr1164341246434221E07136788
chr1164344196434779E07137083
chr1164361436436697E07138807
chr1164367116436878E07139375
chr1164370856437125E07139749
chr1164371396437348E07139803
chr1164375266437614E07140190
chr1164377116437811E07140375
chr1164378576438015E07140521
chr1163544686354685E072-42651
chr1163547476354841E072-42495
chr1163549986355070E072-42266
chr1164013156401384E0723979
chr1164013856401482E0724049
chr1164015886401638E0724252
chr1164017076401771E0724371
chr1164018626401949E0724526
chr1164020246402258E0724688
chr1164024086402503E0725072
chr1164025606402610E0725224
chr1164096216409681E07212285
chr1164130526413169E07215716
chr1164132686413357E07215932
chr1164133926413531E07216056
chr1164143256414425E07216989
chr1164144756414598E07217139
chr1164146696414719E07217333
chr1164148406414894E07217504
chr1164149706415068E07217634
chr1164152206415281E07217884
chr1164153176415409E07217981
chr1164154436415601E07218107
chr1164156146415670E07218278
chr1164157586415808E07218422
chr1164159006416004E07218564
chr1164161006416154E07218764
chr1164162746416392E07218938
chr1164164986416585E07219162
chr1164168506416929E07219514
chr1164170946417144E07219758
chr1164172076417257E07219871
chr1164173076417395E07219971
chr1164182866418336E07220950
chr1164183496418399E07221013
chr1164184686418789E07221132
chr1164188296419173E07221493
chr1164219066422084E07224570
chr1164222446422400E07224908
chr1164225786423186E07225242
chr1164276086427733E07230272
chr1164278976427974E07230561
chr1164279996428054E07230663
chr1164280676428143E07230731
chr1164282426428293E07230906
chr1164284856428535E07231149
chr1164285736428724E07231237
chr1164303676430462E07233031
chr1164311806431255E07233844
chr1164312726431312E07233936
chr1164313496431389E07234013
chr1164367116436878E07239375
chr1164370856437125E07239749
chr1164371396437348E07239803
chr1164415926441643E07244256
chr1163544686354685E073-42651
chr1163547476354841E073-42495
chr1163549986355070E073-42266
chr1163734806373530E073-23806
chr1164094226409617E07312086
chr1164096216409681E07312285
chr1164096866409917E07312350
chr1164100906410210E07312754
chr1164103826410444E07313046
chr1164104766410542E07313140
chr1164130526413169E07315716
chr1164132686413357E07315932
chr1164133926413531E07316056
chr1164143256414425E07316989
chr1164144756414598E07317139
chr1164146696414719E07317333
chr1164164986416585E07319162
chr1164168506416929E07319514
chr1164170946417144E07319758
chr1164172076417257E07319871
chr1164173076417395E07319971
chr1164219066422084E07324570
chr1164222446422400E07324908
chr1164225786423186E07325242
chr1164276086427733E07330272
chr1164278976427974E07330561
chr1164279996428054E07330663
chr1164280676428143E07330731
chr1164282426428293E07330906
chr1164284856428535E07331149
chr1164285736428724E07331237
chr1164311806431255E07333844
chr1164312726431312E07333936
chr1164313496431389E07334013
chr1164318716431993E07334535
chr1164324016432471E07335065
chr1164330726433237E07335736
chr1164341246434221E07336788
chr1164375266437614E07340190
chr1164377116437811E07340375
chr1164378576438015E07340521
chr1164382586438308E07340922
chr1164415926441643E07344256
chr1164025606402610E0745224
chr1164026666402750E0745330
chr1164103826410444E07413046
chr1164104766410542E07413140
chr1164130526413169E07415716
chr1164132686413357E07415932
chr1164133926413531E07416056
chr1164182866418336E07420950
chr1164183496418399E07421013
chr1164184686418789E07421132
chr1164188296419173E07421493
chr1164192726419418E07421936
chr1164195806419637E07422244
chr1164198676419944E07422531
chr1164206626420764E07423326
chr1164208396420879E07423503
chr1164209886421042E07423652
chr1164211236421173E07423787
chr1164213606421410E07424024
chr1164219066422084E07424570
chr1164222446422400E07424908
chr1164225786423186E07425242
chr1164270466427414E07429710
chr1164276086427733E07430272
chr1164278976427974E07430561
chr1164279996428054E07430663
chr1164280676428143E07430731
chr1164282426428293E07430906
chr1164284856428535E07431149
chr1164285736428724E07431237
chr1164303676430462E07433031
chr1164311806431255E07433844
chr1164312726431312E07433936
chr1164313496431389E07434013
chr1164341246434221E07436788
chr1164344196434779E07437083
chr1164358626435916E07438526
chr1164359356436085E07438599
chr1164361436436697E07438807
chr1164367116436878E07439375
chr1164370856437125E07439749
chr1164371396437348E07439803
chr1164375266437614E07440190
chr1164377116437811E07440375
chr1164378576438015E07440521
chr1164382586438308E07440922
chr1164383636438442E07441027
chr1164384856438576E07441149
chr1164386016438651E07441265
chr1164387186438799E07441382
chr1163544686354685E081-42651
chr1163547476354841E081-42495
chr1163549986355070E081-42266
chr1163552426355292E081-42044
chr1163552986355348E081-41988
chr1163726146372664E081-24672
chr1163727286372778E081-24558
chr1163730616373457E081-23879
chr1163734806373530E081-23806
chr1163739236374013E081-23323
chr1163743866374448E081-22888
chr1163745296375189E081-22147
chr1163778686378123E081-19213
chr1163781386378929E081-18407
chr1163834196384675E081-12661
chr1163847196384972E081-12364
chr1164103826410444E08113046
chr1164104766410542E08113140
chr1164130526413169E08115716
chr1164132686413357E08115932
chr1164133926413531E08116056
chr1164168506416929E08119514
chr1164170946417144E08119758
chr1164172076417257E08119871
chr1164173076417395E08119971
chr1164270466427414E08129710
chr1164276086427733E08130272
chr1164278976427974E08130561
chr1164279996428054E08130663
chr1164280676428143E08130731
chr1164282426428293E08130906
chr1164284856428535E08131149
chr1164285736428724E08131237
chr1164293816429421E08132045
chr1164294496429542E08132113
chr1164330726433237E08135736
chr1164356646435761E08138328
chr1164358626435916E08138526
chr1164359356436085E08138599
chr1164361436436697E08138807
chr1164367116436878E08139375
chr1164370856437125E08139749
chr1164371396437348E08139803
chr1164375266437614E08140190
chr1164377116437811E08140375
chr1164378576438015E08140521
chr1164382586438308E08140922
chr1164383636438442E08141027
chr1164384856438576E08141149
chr1164386016438651E08141265
chr1164387186438799E08141382
chr1164415926441643E08144256
chr1163544686354685E082-42651
chr1163547476354841E082-42495
chr1163549986355070E082-42266
chr1163730616373457E082-23879
chr1163734806373530E082-23806
chr1164104766410542E08213140
chr1164130526413169E08215716
chr1164132686413357E08215932
chr1164133926413531E08216056
chr1164282426428293E08230906
chr1164284856428535E08231149
chr1164285736428724E08231237
chr1164293816429421E08232045
chr1164294496429542E08232113
chr1164303676430462E08233031
chr1164311806431255E08233844
chr1164312726431312E08233936
chr1164313496431389E08234013
chr1164318716431993E08234535
chr1164324016432471E08235065
chr1164341246434221E08236788
chr1164344196434779E08237083
chr1164356646435761E08238328
chr1164358626435916E08238526
chr1164359356436085E08238599
chr1164361436436697E08238807
chr1164367116436878E08239375
chr1164370856437125E08239749
chr1164371396437348E08239803
chr1164375266437614E08240190
chr1164377116437811E08240375
chr1164378576438015E08240521
chr1164382586438308E08240922
chr1164383636438442E08241027
chr1164384856438576E08241149










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr1164105776412804E06713241
chr1164393236441160E06741987
chr1164105776412804E06813241
chr1164393236441160E06841987
chr1164105776412804E06913241
chr1164393236441160E06941987
chr1164105776412804E07013241
chr1164393236441160E07041987
chr1164105776412804E07113241
chr1164393236441160E07141987
chr1164105776412804E07213241
chr1164393236441160E07241987
chr1164105776412804E07313241
chr1164393236441160E07341987
chr1164105776412804E07413241
chr1164393236441160E07441987
chr1164105776412804E08113241
chr1164393236441160E08141987
chr1164105776412804E08213241
chr1164393236441160E08241987