rs2103284

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0096 (2890/29916,GnomAD)
A=0097 (2846/29118,TOPMED)
A=0168 (843/5008,1000G)
A=0138 (532/3854,ALSPAC)
A=0133 (492/3708,TWINSUK)
chr16:86413578 (GRCh38.p7) (16q24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
16 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 16NC_000016.10:g.86413578G>A
GRCh37.p13 chr 16NC_000016.9:g.86447184G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.974A=0.026
1000GenomesAmericanSub694G=0.830A=0.170
1000GenomesEast AsianSub1008G=0.700A=0.300
1000GenomesEuropeSub1006G=0.863A=0.137
1000GenomesGlobalStudy-wide5008G=0.832A=0.168
1000GenomesSouth AsianSub978G=0.740A=0.260
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.862A=0.138
The Genome Aggregation DatabaseAfricanSub8714G=0.962A=0.038
The Genome Aggregation DatabaseAmericanSub838G=0.850A=0.150
The Genome Aggregation DatabaseEast AsianSub1618G=0.703A=0.297
The Genome Aggregation DatabaseEuropeSub18444G=0.895A=0.104
The Genome Aggregation DatabaseGlobalStudy-wide29916G=0.903A=0.096
The Genome Aggregation DatabaseOtherSub302G=0.890A=0.110
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.902A=0.097
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.867A=0.133
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs21032840.000735alcohol dependence20201924

eQTL of rs2103284 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2103284 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr168649301486493105E06945830
chr168642969386431079E070-16105
chr168644308986443173E070-4011
chr168644329986443349E070-3835
chr168644335186443526E070-3658
chr168645972186459761E07012537
chr168645976886460085E07012584
chr168647815786478232E07030973
chr168647838986478484E07031205
chr168643187386432090E081-15094
chr168643212086432727E081-14457
chr168643277486432836E081-14348
chr168643285286433056E081-14128
chr168645755886457662E08110374
chr168645802486458374E08110840
chr168645839186458729E08111207



Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr168642792786428105E081-19079