rs2108831

Homo sapiens
G>C / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0168 (5050/29958,GnomAD)
G==0224 (6532/29118,TOPMED)
G==0182 (910/5008,1000G)
G==0064 (246/3854,ALSPAC)
G==0057 (210/3708,TWINSUK)
chr17:56640543 (GRCh38.p7) (17q22)
CD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.56640543G>C
GRCh38.p7 chr 17NC_000017.11:g.56640543G>T
GRCh37.p13 chr 17NC_000017.10:g.54717904G>C
GRCh37.p13 chr 17NC_000017.10:g.54717904G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.459C=0.541
1000GenomesAmericanSub694G=0.080C=0.920
1000GenomesEast AsianSub1008G=0.122C=0.878
1000GenomesEuropeSub1006G=0.081C=0.919
1000GenomesGlobalStudy-wide5008G=0.182C=0.818
1000GenomesSouth AsianSub978G=0.050C=0.950
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.064C=0.936
The Genome Aggregation DatabaseAfricanSub8716G=0.411C=0.589
The Genome Aggregation DatabaseAmericanSub838G=0.080C=0.92,
The Genome Aggregation DatabaseEast AsianSub1612G=0.161C=0.839
The Genome Aggregation DatabaseEuropeSub18490G=0.060C=0.939
The Genome Aggregation DatabaseGlobalStudy-wide29958G=0.168C=0.831
The Genome Aggregation DatabaseOtherSub302G=0.090C=0.91,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.224C=0.775
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.057C=0.943
PMID Title Author Journal
23958962Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene.Gelernter JMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs21088310.0000017cocaine dependence,AA23958962
rs21088310.0000567cocaine dependence23958962

eQTL of rs2108831 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2108831 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.