rs211409

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0140 (4201/29968,GnomAD)
T==0181 (5294/29118,TOPMED)
T==0142 (709/5008,1000G)
T==0107 (413/3854,ALSPAC)
T==0107 (398/3708,TWINSUK)
chr10:32104285 (GRCh38.p7) (10p11.22)
AD
GWASdb2
1   publication(s)
See rs on genome
12 Enhancers around
20 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.32104285T>C
GRCh37.p13 chr 10NC_000010.10:g.32393213T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.330C=0.670
1000GenomesAmericanSub694T=0.140C=0.860
1000GenomesEast AsianSub1008T=0.006C=0.994
1000GenomesEuropeSub1006T=0.101C=0.899
1000GenomesGlobalStudy-wide5008T=0.142C=0.858
1000GenomesSouth AsianSub978T=0.070C=0.930
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.107C=0.893
The Genome Aggregation DatabaseAfricanSub8718T=0.280C=0.720
The Genome Aggregation DatabaseAmericanSub838T=0.160C=0.840
The Genome Aggregation DatabaseEast AsianSub1620T=0.010C=0.990
The Genome Aggregation DatabaseEuropeSub18490T=0.085C=0.914
The Genome Aggregation DatabaseGlobalStudy-wide29968T=0.140C=0.859
The Genome Aggregation DatabaseOtherSub302T=0.090C=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.181C=0.818
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.107C=0.893
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs2114090.00082alcohol dependence20201924

eQTL of rs211409 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs211409 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103234630832346550E067-46663
chr103241203932412089E06818826
chr103241221032412648E06818997
chr103241411532414254E06920902
chr103241427032414356E06921057
chr103242786132428899E06934648
chr103241203932412089E07118826
chr103241358232413632E07120369
chr103241411532414254E07120902
chr103241427032414356E07121057
chr103242769432427791E07134481
chr103234630832346550E073-46663





Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr103234400932344126E067-49087
chr103234413732345903E067-47310
chr103234400932344126E068-49087
chr103234413732345903E068-47310
chr103234400932344126E069-49087
chr103234413732345903E069-47310
chr103234400932344126E070-49087
chr103234413732345903E070-47310
chr103234400932344126E071-49087
chr103234413732345903E071-47310
chr103234400932344126E072-49087
chr103234413732345903E072-47310
chr103234400932344126E073-49087
chr103234413732345903E073-47310
chr103234400932344126E074-49087
chr103234413732345903E074-47310
chr103234400932344126E081-49087
chr103234413732345903E081-47310
chr103234400932344126E082-49087
chr103234413732345903E082-47310