rs211424

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0169 (5078/29964,GnomAD)
T==0226 (6599/29118,TOPMED)
T==0171 (857/5008,1000G)
T==0107 (413/3854,ALSPAC)
T==0107 (398/3708,TWINSUK)
chr10:32109967 (GRCh38.p7) (10p11.22)
AD
GWASdb2
2   publication(s)
See rs on genome
10 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.32109967T>C
GRCh37.p13 chr 10NC_000010.10:g.32398895T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.433C=0.567
1000GenomesAmericanSub694T=0.150C=0.850
1000GenomesEast AsianSub1008T=0.005C=0.995
1000GenomesEuropeSub1006T=0.103C=0.897
1000GenomesGlobalStudy-wide5008T=0.171C=0.829
1000GenomesSouth AsianSub978T=0.070C=0.930
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.107C=0.893
The Genome Aggregation DatabaseAfricanSub8712T=0.380C=0.620
The Genome Aggregation DatabaseAmericanSub838T=0.170C=0.830
The Genome Aggregation DatabaseEast AsianSub1622T=0.010C=0.990
The Genome Aggregation DatabaseEuropeSub18490T=0.085C=0.914
The Genome Aggregation DatabaseGlobalStudy-wide29964T=0.169C=0.830
The Genome Aggregation DatabaseOtherSub302T=0.100C=0.900
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.226C=0.773
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.107C=0.893
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
16385451A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.Grupe AAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs2114240.00079alcohol dependence20201924

eQTL of rs211424 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs211424 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr103241203932412089E06813144
chr103241221032412648E06813315
chr103241411532414254E06915220
chr103241427032414356E06915375
chr103242786132428899E06928966
chr103241203932412089E07113144
chr103241358232413632E07114687
chr103241411532414254E07115220
chr103241427032414356E07115375
chr103242769432427791E07128799