rs2138564

Homo sapiens
C>T
ZNF365 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0428 (12800/29858,GnomAD)
C==0360 (10487/29118,TOPMED)
C==0360 (1801/5008,1000G)
T=0474 (1827/3854,ALSPAC)
T=0473 (1753/3708,TWINSUK)
chr10:62547558 (GRCh38.p7) (10q21.2)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.62547558C>T
GRCh37.p13 chr 10NC_000010.10:g.64307317C>T
ZNF365 RefSeqGeneNG_021209.1:g.178402C>T

Gene: ZNF365, zinc finger protein 365(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ZNF365 transcript variant CNM_199451.2:c.N/AIntron Variant
ZNF365 transcript variant DNM_199452.3:c.N/AIntron Variant
ZNF365 transcript variant ANM_014951.2:c.N/AGenic Downstream Transcript Variant
ZNF365 transcript variant BNM_199450.2:c.N/AGenic Downstream Transcript Variant
ZNF365 transcript variant X2XM_017015938.1:c.N/AGenic Upstream Transcript Variant
ZNF365 transcript variant X3XM_017015939.1:c.N/AGenic Upstream Transcript Variant
ZNF365 transcript variant X4XM_017015940.1:c.N/AGenic Upstream Transcript Variant
ZNF365 transcript variant X5XM_017015941.1:c.N/AGenic Upstream Transcript Variant
ZNF365 transcript variant X1XM_017015937.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.099T=0.901
1000GenomesAmericanSub694C=0.560T=0.440
1000GenomesEast AsianSub1008C=0.403T=0.597
1000GenomesEuropeSub1006C=0.504T=0.496
1000GenomesGlobalStudy-wide5008C=0.360T=0.640
1000GenomesSouth AsianSub978C=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.526T=0.474
The Genome Aggregation DatabaseAfricanSub8716C=0.160T=0.840
The Genome Aggregation DatabaseAmericanSub834C=0.480T=0.520
The Genome Aggregation DatabaseEast AsianSub1598C=0.401T=0.599
The Genome Aggregation DatabaseEuropeSub18410C=0.552T=0.447
The Genome Aggregation DatabaseGlobalStudy-wide29858C=0.428T=0.571
The Genome Aggregation DatabaseOtherSub300C=0.630T=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.360T=0.639
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.527T=0.473
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs21385640.00079alcohol dependence20201924

eQTL of rs2138564 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2138564 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr106427718464277238E067-30079
chr106427727564277329E067-29988
chr106432324764323314E06715930
chr106432338464323558E06716067
chr106432368064324605E06716363
chr106427687364276969E068-30348
chr106427718464277238E068-30079
chr106427727564277329E068-29988
chr106427771164277922E068-29395
chr106432324764323314E06815930
chr106432338464323558E06816067
chr106425822164258329E069-48988
chr106432324764323314E06915930
chr106432338464323558E06916067
chr106427687364276969E071-30348
chr106427718464277238E071-30079
chr106427727564277329E071-29988
chr106427771164277922E071-29395
chr106431441764314753E0717100
chr106431478964314850E0717472
chr106431491864314998E0717601
chr106432285264322931E07115535
chr106432295664323059E07115639
chr106432310164323151E07115784
chr106432324764323314E07115930
chr106432338464323558E07116067
chr106435365464354391E07146337
chr106435439464354569E07147077
chr106432285264322931E07215535
chr106432295664323059E07215639
chr106432310164323151E07215784
chr106432324764323314E07215930
chr106432338464323558E07216067
chr106432368064324605E07216363
chr106427687364276969E073-30348
chr106427718464277238E073-30079
chr106427727564277329E073-29988
chr106427687364276969E074-30348
chr106427718464277238E074-30079
chr106427727564277329E074-29988
chr106432258164322627E07415264
chr106432285264322931E07415535
chr106432295664323059E07415639
chr106432310164323151E07415784
chr106432324764323314E07415930
chr106432338464323558E07416067
chr106432368064324605E07416363
chr106432310164323151E08115784