rs2154225

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
C==0393 (11774/29924,GnomAD)
C==0468 (13645/29118,TOPMED)
C==0433 (2170/5008,1000G)
C==0234 (900/3854,ALSPAC)
C==0232 (862/3708,TWINSUK)
chr6:52198303 (GRCh38.p7) (6p12.2)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.52198303C>T
GRCh37.p13 chr 6NC_000006.11:g.52063101C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.818T=0.182
1000GenomesAmericanSub694C=0.240T=0.760
1000GenomesEast AsianSub1008C=0.293T=0.707
1000GenomesEuropeSub1006C=0.248T=0.752
1000GenomesGlobalStudy-wide5008C=0.433T=0.567
1000GenomesSouth AsianSub978C=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.234T=0.766
The Genome Aggregation DatabaseAfricanSub8720C=0.752T=0.248
The Genome Aggregation DatabaseAmericanSub838C=0.250T=0.750
The Genome Aggregation DatabaseEast AsianSub1608C=0.287T=0.713
The Genome Aggregation DatabaseEuropeSub18456C=0.240T=0.759
The Genome Aggregation DatabaseGlobalStudy-wide29924C=0.393T=0.606
The Genome Aggregation DatabaseOtherSub302C=0.360T=0.640
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.468T=0.531
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.232T=0.768
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs21542253.9E-06alcohol and nictotine co-dependence20158304

eQTL of rs2154225 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2154225 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.