rs2154294

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0437 (13062/29854,GnomAD)
A==0462 (13459/29118,TOPMED)
A==0399 (2000/5008,1000G)
A==0495 (1909/3854,ALSPAC)
A==0497 (1844/3708,TWINSUK)
chr14:42186072 (GRCh38.p7) (14q21.1)
AD
GWASdb2 | GWASCatalog
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.42186072A>G
GRCh37.p13 chr 14NC_000014.8:g.42655275A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.445G=0.555
1000GenomesAmericanSub694A=0.480G=0.520
1000GenomesEast AsianSub1008A=0.193G=0.807
1000GenomesEuropeSub1006A=0.473G=0.527
1000GenomesGlobalStudy-wide5008A=0.399G=0.601
1000GenomesSouth AsianSub978A=0.420G=0.580
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.495G=0.505
The Genome Aggregation DatabaseAfricanSub8706A=0.440G=0.560
The Genome Aggregation DatabaseAmericanSub832A=0.470G=0.530
The Genome Aggregation DatabaseEast AsianSub1598A=0.183G=0.817
The Genome Aggregation DatabaseEuropeSub18418A=0.456G=0.544
The Genome Aggregation DatabaseGlobalStudy-wide29854A=0.437G=0.562
The Genome Aggregation DatabaseOtherSub300A=0.490G=0.510
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.462G=0.537
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.497G=0.503
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs21542940.000003alcoholism (12-month weekly alcohol consumption)21529783
rs21542943.00E-06alcohol dependence21529783

eQTL of rs2154294 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2154294 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr144269233642692777E06737061
chr144269137042691639E07036095
chr144269205042692186E08236775
chr144269233642692777E08237061