rs2157949

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0239 (7177/29942,GnomAD)
G==0242 (7056/29118,TOPMED)
G==0173 (865/5008,1000G)
G==0293 (1128/3854,ALSPAC)
G==0295 (1094/3708,TWINSUK)
chr7:107729091 (GRCh38.p7) (7q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
86 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.107729091G>A
GRCh37.p13 chr 7NC_000007.13:g.107369536G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.191A=0.809
1000GenomesAmericanSub694G=0.230A=0.770
1000GenomesEast AsianSub1008G=0.017A=0.983
1000GenomesEuropeSub1006G=0.297A=0.703
1000GenomesGlobalStudy-wide5008G=0.173A=0.827
1000GenomesSouth AsianSub978G=0.140A=0.860
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.293A=0.707
The Genome Aggregation DatabaseAfricanSub8712G=0.210A=0.790
The Genome Aggregation DatabaseAmericanSub836G=0.170A=0.830
The Genome Aggregation DatabaseEast AsianSub1620G=0.011A=0.989
The Genome Aggregation DatabaseEuropeSub18472G=0.276A=0.724
The Genome Aggregation DatabaseGlobalStudy-wide29942G=0.239A=0.760
The Genome Aggregation DatabaseOtherSub302G=0.300A=0.700
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.242A=0.757
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.295A=0.705
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs21579496.12E-05alcohol consumption23743675

eQTL of rs2157949 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2157949 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7107333486107333578E067-35958
chr7107333824107334105E067-35431
chr7107334175107334517E067-35019
chr7107334625107335182E067-34354
chr7107335233107335327E067-34209
chr7107383023107383099E06713487
chr7107386669107386772E06717133
chr7107387624107387709E06718088
chr7107387798107387880E06718262
chr7107333486107333578E068-35958
chr7107333824107334105E068-35431
chr7107334175107334517E068-35019
chr7107334625107335182E068-34354
chr7107335233107335327E068-34209
chr7107341168107341256E068-28280
chr7107341276107341497E068-28039
chr7107382753107382818E06813217
chr7107386669107386772E06817133
chr7107387624107387709E06818088
chr7107387798107387880E06818262
chr7107387932107387978E06818396
chr7107388350107388400E06818814
chr7107333486107333578E069-35958
chr7107333824107334105E069-35431
chr7107334175107334517E069-35019
chr7107334625107335182E069-34354
chr7107335233107335327E069-34209
chr7107335529107335618E069-33918
chr7107337294107337374E069-32162
chr7107337495107337545E069-31991
chr7107383023107383099E06913487
chr7107386669107386772E06917133
chr7107387624107387709E06918088
chr7107387798107387880E06918262
chr7107387932107387978E06918396
chr7107332948107333294E070-36242
chr7107333486107333578E070-35958
chr7107333824107334105E070-35431
chr7107334175107334517E070-35019
chr7107334625107335182E070-34354
chr7107335233107335327E070-34209
chr7107335529107335618E070-33918
chr7107335644107335829E070-33707
chr7107337495107337545E070-31991
chr7107337639107338679E070-30857
chr7107383023107383099E07013487
chr7107386669107386772E07017133
chr7107387798107387880E07018262
chr7107387932107387978E07018396
chr7107388350107388400E07018814
chr7107332129107332230E071-37306
chr7107332267107332442E071-37094
chr7107332948107333294E071-36242
chr7107333486107333578E071-35958
chr7107333824107334105E071-35431
chr7107335233107335327E071-34209
chr7107337495107337545E071-31991
chr7107337639107338679E071-30857
chr7107383023107383099E07113487
chr7107333824107334105E072-35431
chr7107334175107334517E072-35019
chr7107334625107335182E072-34354
chr7107337639107338679E072-30857
chr7107383023107383099E07213487
chr7107386669107386772E07217133
chr7107333824107334105E073-35431
chr7107334175107334517E073-35019
chr7107334625107335182E073-34354
chr7107335233107335327E073-34209
chr7107337639107338679E073-30857
chr7107333486107333578E074-35958
chr7107333824107334105E074-35431
chr7107334175107334517E074-35019
chr7107335233107335327E074-34209
chr7107333824107334105E081-35431
chr7107337639107338679E081-30857
chr7107338996107339076E081-30460
chr7107334175107334517E082-35019
chr7107334625107335182E082-34354
chr7107337294107337374E082-32162
chr7107337495107337545E082-31991
chr7107337639107338679E082-30857
chr7107386669107386772E08217133
chr7107387798107387880E08218262
chr7107387932107387978E08218396
chr7107388350107388400E08218814










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7107383118107385525E06713582
chr7107383118107385525E06813582
chr7107383118107385525E06913582
chr7107383118107385525E07013582
chr7107383118107385525E07113582
chr7107383118107385525E07213582
chr7107383118107385525E07313582
chr7107383118107385525E07413582
chr7107383118107385525E08113582
chr7107383118107385525E08213582