rs2181666

Homo sapiens
A>G
MYO16 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G=0041 (1255/29974,GnomAD)
G=0024 (714/29118,TOPMED)
G=0028 (141/5008,1000G)
G=0047 (182/3854,ALSPAC)
G=0049 (183/3708,TWINSUK)
chr13:109204497 (GRCh38.p7) (13q33.3)
AD
GWASdb2
1   publication(s)
See rs on genome
38 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.109204497A>G
GRCh37.p13 chr 13NC_000013.10:g.109856845A>G

Gene: MYO16, myosin XVI(plus strand)

Molecule type Change Amino acid[Codon] SO Term
MYO16 transcript variant 1NM_001198950.1:c.N/AIntron Variant
MYO16 transcript variant 2NM_015011.1:c.N/AIntron Variant
MYO16 transcript variant X1XM_011521062.1:c.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.999G=0.001
1000GenomesAmericanSub694A=0.980G=0.020
1000GenomesEast AsianSub1008A=1.000G=0.000
1000GenomesEuropeSub1006A=0.942G=0.058
1000GenomesGlobalStudy-wide5008A=0.972G=0.028
1000GenomesSouth AsianSub978A=0.930G=0.070
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.953G=0.047
The Genome Aggregation DatabaseAfricanSub8726A=0.989G=0.011
The Genome Aggregation DatabaseAmericanSub838A=0.980G=0.020
The Genome Aggregation DatabaseEast AsianSub1616A=1.000G=0.000
The Genome Aggregation DatabaseEuropeSub18492A=0.938G=0.061
The Genome Aggregation DatabaseGlobalStudy-wide29974A=0.958G=0.041
The Genome Aggregation DatabaseOtherSub302A=0.960G=0.040
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.975G=0.024
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.951G=0.049
PMID Title Author Journal
23953852Genome-wide association studies of maximum number of drinks.Pan YJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs21816661.52E-05alcohol consumption23953852

eQTL of rs2181666 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2181666 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr13109833188109833816E067-23029
chr13109895164109896513E06738319
chr13109863485109863537E0686640
chr13109863618109863662E0686773
chr13109811953109812183E069-44662
chr13109812185109812287E069-44558
chr13109833188109833816E069-23029
chr13109895164109896513E06938319
chr13109813678109813910E070-42935
chr13109823407109823501E070-33344
chr13109824263109824313E070-32532
chr13109824416109824486E070-32359
chr13109824583109824673E070-32172
chr13109895164109896513E07038319
chr13109896528109896648E07039683
chr13109896665109897420E07039820
chr13109814359109815457E071-41388
chr13109811953109812183E072-44662
chr13109812185109812287E072-44558
chr13109895164109896513E07238319
chr13109809280109809586E073-47259
chr13109809639109810284E073-46561
chr13109811953109812183E074-44662
chr13109812185109812287E074-44558
chr13109812439109812558E074-44287
chr13109812736109813551E074-43294
chr13109833188109833816E074-23029
chr13109806916109807253E081-49592
chr13109807278109808314E081-48531
chr13109808333109809216E081-47629
chr13109809280109809586E081-47259
chr13109809639109810284E081-46561
chr13109824263109824313E081-32532
chr13109807278109808314E082-48531
chr13109808333109809216E082-47629
chr13109849392109849980E082-6865
chr13109896528109896648E08239683
chr13109896665109897420E08239820