rs2188563

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
G==0248 (7442/29932,GnomAD)
G==0259 (7550/29118,TOPMED)
G==0181 (904/5008,1000G)
G==0296 (1140/3854,ALSPAC)
G==0297 (1102/3708,TWINSUK)
chr7:107733426 (GRCh38.p7) (7q22.3)
AD
GWASdb2
1   publication(s)
See rs on genome
86 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 7NC_000007.14:g.107733426G>A
GRCh37.p13 chr 7NC_000007.13:g.107373871G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.214A=0.786
1000GenomesAmericanSub694G=0.230A=0.770
1000GenomesEast AsianSub1008G=0.017A=0.983
1000GenomesEuropeSub1006G=0.304A=0.696
1000GenomesGlobalStudy-wide5008G=0.181A=0.819
1000GenomesSouth AsianSub978G=0.140A=0.860
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.296A=0.704
The Genome Aggregation DatabaseAfricanSub8712G=0.237A=0.763
The Genome Aggregation DatabaseAmericanSub834G=0.180A=0.820
The Genome Aggregation DatabaseEast AsianSub1622G=0.011A=0.989
The Genome Aggregation DatabaseEuropeSub18464G=0.277A=0.722
The Genome Aggregation DatabaseGlobalStudy-wide29932G=0.248A=0.751
The Genome Aggregation DatabaseOtherSub300G=0.310A=0.690
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.259A=0.740
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.297A=0.703
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs21885636.04E-05alcohol consumption23743675

eQTL of rs2188563 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2188563 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr7107333486107333578E067-40293
chr7107333824107334105E067-39766
chr7107334175107334517E067-39354
chr7107334625107335182E067-38689
chr7107335233107335327E067-38544
chr7107383023107383099E0679152
chr7107386669107386772E06712798
chr7107387624107387709E06713753
chr7107387798107387880E06713927
chr7107333486107333578E068-40293
chr7107333824107334105E068-39766
chr7107334175107334517E068-39354
chr7107334625107335182E068-38689
chr7107335233107335327E068-38544
chr7107341168107341256E068-32615
chr7107341276107341497E068-32374
chr7107382753107382818E0688882
chr7107386669107386772E06812798
chr7107387624107387709E06813753
chr7107387798107387880E06813927
chr7107387932107387978E06814061
chr7107388350107388400E06814479
chr7107333486107333578E069-40293
chr7107333824107334105E069-39766
chr7107334175107334517E069-39354
chr7107334625107335182E069-38689
chr7107335233107335327E069-38544
chr7107335529107335618E069-38253
chr7107337294107337374E069-36497
chr7107337495107337545E069-36326
chr7107383023107383099E0699152
chr7107386669107386772E06912798
chr7107387624107387709E06913753
chr7107387798107387880E06913927
chr7107387932107387978E06914061
chr7107332948107333294E070-40577
chr7107333486107333578E070-40293
chr7107333824107334105E070-39766
chr7107334175107334517E070-39354
chr7107334625107335182E070-38689
chr7107335233107335327E070-38544
chr7107335529107335618E070-38253
chr7107335644107335829E070-38042
chr7107337495107337545E070-36326
chr7107337639107338679E070-35192
chr7107383023107383099E0709152
chr7107386669107386772E07012798
chr7107387798107387880E07013927
chr7107387932107387978E07014061
chr7107388350107388400E07014479
chr7107332129107332230E071-41641
chr7107332267107332442E071-41429
chr7107332948107333294E071-40577
chr7107333486107333578E071-40293
chr7107333824107334105E071-39766
chr7107335233107335327E071-38544
chr7107337495107337545E071-36326
chr7107337639107338679E071-35192
chr7107383023107383099E0719152
chr7107333824107334105E072-39766
chr7107334175107334517E072-39354
chr7107334625107335182E072-38689
chr7107337639107338679E072-35192
chr7107383023107383099E0729152
chr7107386669107386772E07212798
chr7107333824107334105E073-39766
chr7107334175107334517E073-39354
chr7107334625107335182E073-38689
chr7107335233107335327E073-38544
chr7107337639107338679E073-35192
chr7107333486107333578E074-40293
chr7107333824107334105E074-39766
chr7107334175107334517E074-39354
chr7107335233107335327E074-38544
chr7107333824107334105E081-39766
chr7107337639107338679E081-35192
chr7107338996107339076E081-34795
chr7107334175107334517E082-39354
chr7107334625107335182E082-38689
chr7107337294107337374E082-36497
chr7107337495107337545E082-36326
chr7107337639107338679E082-35192
chr7107386669107386772E08212798
chr7107387798107387880E08213927
chr7107387932107387978E08214061
chr7107388350107388400E08214479










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr7107383118107385525E0679247
chr7107383118107385525E0689247
chr7107383118107385525E0699247
chr7107383118107385525E0709247
chr7107383118107385525E0719247
chr7107383118107385525E0729247
chr7107383118107385525E0739247
chr7107383118107385525E0749247
chr7107383118107385525E0819247
chr7107383118107385525E0829247