rs2206266

Homo sapiens
T>C
LOC105372522 : Non Coding Transcript Variant
Check p-value
SNV (Single Nucleotide Variation)
C=0491 (14695/29896,GnomAD)
C=0421 (12258/29118,TOPMED)
T==0460 (2302/5008,1000G)
C=0483 (1861/3854,ALSPAC)
C=0472 (1749/3708,TWINSUK)
chr20:8968417 (GRCh38.p7) (20p12.3)
AD
GWASdb2
1   publication(s)
See rs on genome
1 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 20NC_000020.11:g.8968417T>C
GRCh37.p13 chr 20NC_000020.10:g.8949064T>C

Gene: LOC105372522, uncharacterized LOC105372522(plus strand)

Molecule type Change Amino acid[Codon] SO Term
LOC105372522 transcript variant X1XR_001754736.1:n....XR_001754736.1:n.1840T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X2XR_001754738.1:n....XR_001754738.1:n.1846T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X3XR_001754739.1:n....XR_001754739.1:n.1794T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X4XR_001754740.1:n....XR_001754740.1:n.1743T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X5XR_937244.2:n.167...XR_937244.2:n.1676T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X6XR_001754741.1:n....XR_001754741.1:n.1723T>CT>CNon Coding Transcript Variant
LOC105372522 transcript variant X7XR_001754742.1:n....XR_001754742.1:n.1917T>CT>CNon Coding Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.597C=0.403
1000GenomesAmericanSub694T=0.380C=0.620
1000GenomesEast AsianSub1008T=0.256C=0.744
1000GenomesEuropeSub1006T=0.560C=0.440
1000GenomesGlobalStudy-wide5008T=0.460C=0.540
1000GenomesSouth AsianSub978T=0.440C=0.560
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.517C=0.483
The Genome Aggregation DatabaseAfricanSub8698T=0.583C=0.417
The Genome Aggregation DatabaseAmericanSub836T=0.360C=0.640
The Genome Aggregation DatabaseEast AsianSub1612T=0.246C=0.754
The Genome Aggregation DatabaseEuropeSub18448T=0.502C=0.498
The Genome Aggregation DatabaseGlobalStudy-wide29896T=0.508C=0.491
The Genome Aggregation DatabaseOtherSub302T=0.550C=0.450
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.579C=0.421
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.528C=0.472
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs22062660.00071alcohol dependence21314694

eQTL of rs2206266 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2206266 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr2089276188928232E071-20832