SNP Detail Info-rs2253162

Organism: Homo sapiens

Alleles: A>G / A>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0381 (11412/29946,GnomAD)
G=0355 (10351/29118,TOPMED)
G=0403 (2020/5008,1000G)
G=0414 (1594/3854,ALSPAC)
G=0420 (1557/3708,TWINSUK)

Position: chr8:126322765 (GRCh38.p7) (8q24.21)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	A=0.783	G=0.217
1000Genomes	American	Sub	694	A=0.570	G=0.430
1000Genomes	East Asian	Sub	1008	A=0.379	G=0.621
1000Genomes	Europe	Sub	1006	A=0.585	G=0.415
1000Genomes	Global	Study-wide	5008	A=0.597	G=0.403
1000Genomes	South Asian	Sub	978	A=0.600	G=0.400
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	A=0.586	G=0.414
The Genome Aggregation Database	African	Sub	8720	A=0.743	G=0.257
The Genome Aggregation Database	American	Sub	836	A=0.550	G=0.450
The Genome Aggregation Database	East Asian	Sub	1618	A=0.389	G=0.611
The Genome Aggregation Database	Europe	Sub	18472	A=0.584	G=0.416
The Genome Aggregation Database	Global	Study-wide	29946	A=0.618	G=0.381
The Genome Aggregation Database	Other	Sub	300	A=0.610	G=0.390
Trans-Omics for Precision Medicine	Global	Study-wide	29118	A=0.644	G=0.355
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	A=0.580	G=0.420

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs2253162	9.5E-05	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs2253162