rs2256182

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0189 (5661/29958,GnomAD)
T==0157 (4586/29118,TOPMED)
T==0111 (557/5008,1000G)
T==0240 (926/3854,ALSPAC)
T==0246 (913/3708,TWINSUK)
chr8:92555837 (GRCh38.p7) (8q22.1)
AD
GWASdb2
1   publication(s)
See rs on genome
61 Enhancers around
6 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.92555837T>C
GRCh37.p13 chr 8NC_000008.10:g.93568065T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.061C=0.939
1000GenomesAmericanSub694T=0.200C=0.800
1000GenomesEast AsianSub1008T=0.012C=0.988
1000GenomesEuropeSub1006T=0.250C=0.750
1000GenomesGlobalStudy-wide5008T=0.111C=0.889
1000GenomesSouth AsianSub978T=0.080C=0.920
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.240C=0.760
The Genome Aggregation DatabaseAfricanSub8730T=0.083C=0.917
The Genome Aggregation DatabaseAmericanSub838T=0.180C=0.820
The Genome Aggregation DatabaseEast AsianSub1608T=0.016C=0.984
The Genome Aggregation DatabaseEuropeSub18482T=0.253C=0.746
The Genome Aggregation DatabaseGlobalStudy-wide29958T=0.189C=0.811
The Genome Aggregation DatabaseOtherSub300T=0.240C=0.760
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.157C=0.842
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.246C=0.754
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs22561820.0006alcohol dependence20201924

eQTL of rs2256182 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2256182 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr89352566693525886E067-42179
chr89352595093526019E067-42046
chr89352941093529516E067-38549
chr89352996093530041E067-38024
chr89353015093530339E067-37726
chr89355064393550826E069-17239
chr89355201893552913E069-15152
chr89352638393526556E070-41509
chr89352855093528856E070-39209
chr89353100993531059E070-37006
chr89353107293531112E070-36953
chr89357665293576789E0708587
chr89361518493615262E07047119
chr89361532393615475E07047258
chr89353777293537856E071-30209
chr89355064393550826E071-17239
chr89355170593551827E071-16238
chr89355187493551971E071-16094
chr89355201893552913E071-15152
chr89356801393568097E0710
chr89356812193568355E07156
chr89359973193600188E07131666
chr89360019793600352E07132132
chr89355064393550826E072-17239
chr89355170593551827E072-16238
chr89355187493551971E072-16094
chr89355201893552913E072-15152
chr89359973193600188E07231666
chr89360019793600352E07232132
chr89355201893552913E074-15152
chr89359952093599664E07431455
chr89359973193600188E07431666
chr89360019793600352E07432132
chr89351812593518997E081-49068
chr89352083293520973E081-47092
chr89352103493521084E081-46981
chr89352112893521195E081-46870
chr89352126293522368E081-45697
chr89352507593525125E081-42940
chr89352526893525469E081-42596
chr89352566693525886E081-42179
chr89352595093526019E081-42046
chr89352619593526263E081-41802
chr89352638393526556E081-41509
chr89352855093528856E081-39209
chr89357665293576789E0818587
chr89357693393576983E0818868
chr89361715693617442E08149091
chr89361763793617723E08149572
chr89361773293617863E08149667
chr89352566693525886E082-42179
chr89352595093526019E082-42046
chr89352619593526263E082-41802
chr89352638393526556E082-41509
chr89352855093528856E082-39209
chr89353143093531665E082-36400
chr89353180093531850E082-36215
chr89353187493531959E082-36106
chr89353200193532073E082-35992
chr89353239593532785E082-35280
chr89353309293533287E082-34778








Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr89352658493528492E067-39573
chr89352658493528492E071-39573
chr89352658493528492E072-39573
chr89352658493528492E073-39573
chr89352658493528492E074-39573
chr89352658493528492E082-39573