SNP Detail Info-rs2274853

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 9	NC_000009.12:g.132238978G>A
GRCh38.p7 chr 9	NC_000009.12:g.132238978G>C
GRCh37.p13 chr 9	NC_000009.11:g.135114365G>A
GRCh37.p13 chr 9	NC_000009.11:g.135114365G>C

Gene: NTNG2, netrin G2(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
NTNG2 transcript	NM_032536.2:c.	N/A	Intron Variant
NTNG2 transcript variant X15	XM_006717304.3:c.	N/A	Intron Variant
NTNG2 transcript variant X1	XM_011519094.2:c.	N/A	Intron Variant
NTNG2 transcript variant X3	XM_011519096.2:c.	N/A	Intron Variant
NTNG2 transcript variant X4	XM_011519097.2:c.	N/A	Intron Variant
NTNG2 transcript variant X5	XM_011519098.2:c.	N/A	Intron Variant
NTNG2 transcript variant X6	XM_011519099.2:c.	N/A	Intron Variant
NTNG2 transcript variant X8	XM_011519100.2:c.	N/A	Intron Variant
NTNG2 transcript variant X9	XM_011519102.2:c.	N/A	Intron Variant
NTNG2 transcript variant X10	XM_011519103.2:c.	N/A	Intron Variant
NTNG2 transcript variant X12	XM_011519104.2:c.	N/A	Intron Variant
NTNG2 transcript variant X11	XM_011519105.2:c.	N/A	Intron Variant
NTNG2 transcript variant X13	XM_011519106.2:c.	N/A	Intron Variant
NTNG2 transcript variant X16	XM_011519107.2:c.	N/A	Intron Variant
NTNG2 transcript variant X21	XM_011519112.2:c.	N/A	Intron Variant
NTNG2 transcript variant X23	XM_011519113.2:c.	N/A	Intron Variant
NTNG2 transcript variant X2	XM_017015212.1:c.	N/A	Intron Variant
NTNG2 transcript variant X7	XM_017015213.1:c.	N/A	Intron Variant
NTNG2 transcript variant X14	XM_017015214.1:c.	N/A	Intron Variant
NTNG2 transcript variant X18	XM_017015215.1:c.	N/A	Genic Upstream Transcript Variant
NTNG2 transcript variant X17	XM_011519108.2:c.	N/A	Genic Downstream Transcript Variant
NTNG2 transcript variant X19	XM_011519109.2:c.	N/A	Genic Downstream Transcript Variant
NTNG2 transcript variant X20	XM_011519110.2:c.	N/A	Genic Downstream Transcript Variant
NTNG2 transcript variant X22	XM_017015216.1:c.	N/A	Genic Downstream Transcript Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.777	A=0.223
1000Genomes	American	Sub	694	G=0.650	A=0.350
1000Genomes	East Asian	Sub	1008	G=0.680	A=0.320
1000Genomes	Europe	Sub	1006	G=0.850	A=0.150
1000Genomes	Global	Study-wide	5008	G=0.740	A=0.260
1000Genomes	South Asian	Sub	978	G=0.700	A=0.300
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.859	A=0.141
The Exome Aggregation Consortium	American	Sub	11270	G=0.507	A=0.492
The Exome Aggregation Consortium	Asian	Sub	15596	G=0.631	A=0.368
The Exome Aggregation Consortium	Europe	Sub	32086	G=0.724	A=0.275
The Exome Aggregation Consortium	Global	Study-wide	59466	G=0.659	A=0.341
The Exome Aggregation Consortium	Other	Sub	514	G=0.700	A=0.300
The Genome Aggregation Database	African	Sub	8724	G=0.781	A=0.219
The Genome Aggregation Database	American	Sub	838	G=0.580	A=0.420
The Genome Aggregation Database	East Asian	Sub	1616	G=0.660	A=0.340
The Genome Aggregation Database	Europe	Sub	18466	G=0.837	A=0.162
The Genome Aggregation Database	Global	Study-wide	29946	G=0.803	A=0.196
The Genome Aggregation Database	Other	Sub	302	G=0.740	A=0.260
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.791	A=0.208
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.862	A=0.138

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

P-Value

SNP ID	p-value	Traits	Study
rs2274853	0.000663	alcohol dependence	20201924

eQTL of rs2274853 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs2274853 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs2274853

Genomic Coordinates

Gene: NTNG2, netrin G2(plus strand)

Population Frequency

P-Value

eQTL of rs2274853 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs2274853 in Fetal Brain

Genomic View

Chromatin Interaction