rs2282424

Homo sapiens
G>A / G>C
None
Check p-value
SNV (Single Nucleotide Variation)
A=0097 (2925/29976,GnomAD)
A=0102 (2971/29118,TOPMED)
A=0145 (724/5008,1000G)
A=0066 (256/3854,ALSPAC)
A=0062 (231/3708,TWINSUK)
chr13:97136192 (GRCh38.p7) (13q32.1)
ND
GWASdb2
1   publication(s)
See rs on genome
6 Enhancers around
14 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.97136192G>A
GRCh38.p7 chr 13NC_000013.11:g.97136192G>C
GRCh37.p13 chr 13NC_000013.10:g.97788446G>A
GRCh37.p13 chr 13NC_000013.10:g.97788446G>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.837A=0.163
1000GenomesAmericanSub694G=0.890A=0.110
1000GenomesEast AsianSub1008G=0.798A=0.202
1000GenomesEuropeSub1006G=0.933A=0.067
1000GenomesGlobalStudy-wide5008G=0.855A=0.145
1000GenomesSouth AsianSub978G=0.840A=0.160
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.934A=0.066
The Genome Aggregation DatabaseAfricanSub8730G=0.866C=0.000
The Genome Aggregation DatabaseAmericanSub836G=0.910C=0.00,
The Genome Aggregation DatabaseEast AsianSub1608G=0.823C=0.001
The Genome Aggregation DatabaseEuropeSub18500G=0.926C=0.000
The Genome Aggregation DatabaseGlobalStudy-wide29976G=0.902C=0.000
The Genome Aggregation DatabaseOtherSub302G=0.870C=0.00,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.898A=0.102
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.938A=0.062
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs22824242.98E-05alcohol and nictotine co-dependence20158304

eQTL of rs2282424 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2282424 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr133699450336995063E067-15804
chr133699450336995063E068-15804
chr133699442936994481E071-16386
chr133699450336995063E071-15804
chr133699442936994481E072-16386
chr133699450336995063E072-15804




Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr133700551637005581E067-5286
chr133700563037007439E067-3428
chr133700441637004471E068-6396
chr133700551637005581E068-5286
chr133700563037007439E068-3428
chr133700551637005581E069-5286
chr133700563037007439E069-3428
chr133700441637004471E072-6396
chr133700551637005581E072-5286
chr133700563037007439E072-3428
chr133700551637005581E073-5286
chr133700563037007439E073-3428
chr133700563037007439E074-3428
chr133700563037007439E082-3428