rs2325777

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0125 (3748/29954,GnomAD)
T=0101 (2950/29118,TOPMED)
T=0110 (550/5008,1000G)
T=0158 (610/3854,ALSPAC)
T=0152 (564/3708,TWINSUK)
chr8:57601527 (GRCh38.p7) (8q12.1)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 8NC_000008.11:g.57601527C>T
GRCh37.p13 chr 8NC_000008.10:g.58514086C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.985T=0.015
1000GenomesAmericanSub694C=0.960T=0.040
1000GenomesEast AsianSub1008C=0.824T=0.176
1000GenomesEuropeSub1006C=0.849T=0.151
1000GenomesGlobalStudy-wide5008C=0.890T=0.110
1000GenomesSouth AsianSub978C=0.830T=0.170
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.842T=0.158
The Genome Aggregation DatabaseAfricanSub8720C=0.966T=0.034
The Genome Aggregation DatabaseAmericanSub838C=0.930T=0.070
The Genome Aggregation DatabaseEast AsianSub1614C=0.811T=0.189
The Genome Aggregation DatabaseEuropeSub18480C=0.835T=0.164
The Genome Aggregation DatabaseGlobalStudy-wide29954C=0.874T=0.125
The Genome Aggregation DatabaseOtherSub302C=0.840T=0.160
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.898T=0.101
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.848T=0.152
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs23257770.00017alcohol dependence20201924

eQTL of rs2325777 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2325777 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr85854750158547599E07033415
chr85854770658547793E07033620
chr85854816658548441E07034080
chr85854844758548497E07034361
chr85849915158499643E071-14443
chr85850002258500289E071-13797
chr85850002258500289E072-13797