rs235786

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0459 (13732/29864,GnomAD)
T=0460 (13410/29114,TOPMED)
T=0495 (2477/5008,1000G)
T=0436 (1681/3854,ALSPAC)
T=0434 (1609/3708,TWINSUK)
chr13:52785150 (GRCh38.p7) (13q14.3)
AD
GWASdb2
1   publication(s)
See rs on genome
147 Enhancers around
7 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.52785150C>T
GRCh37.p13 chr 13NC_000013.10:g.53359285C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.596T=0.404
1000GenomesAmericanSub694C=0.490T=0.510
1000GenomesEast AsianSub1008C=0.238T=0.762
1000GenomesEuropeSub1006C=0.539T=0.461
1000GenomesGlobalStudy-wide5008C=0.505T=0.495
1000GenomesSouth AsianSub978C=0.640T=0.360
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.564T=0.436
The Genome Aggregation DatabaseAfricanSub8686C=0.580T=0.420
The Genome Aggregation DatabaseAmericanSub836C=0.490T=0.510
The Genome Aggregation DatabaseEast AsianSub1616C=0.244T=0.756
The Genome Aggregation DatabaseEuropeSub18424C=0.551T=0.448
The Genome Aggregation DatabaseGlobalStudy-wide29864C=0.540T=0.459
The Genome Aggregation DatabaseOtherSub302C=0.450T=0.550
Trans-Omics for Precision MedicineGlobalStudy-wide29114C=0.539T=0.460
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.566T=0.434
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs2357860.00028alcohol dependence(early age of onset)20201924
rs2357860.00065alcohol dependence20201924

eQTL of rs235786 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs235786 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr135335669953357069E067-2216
chr135335710053357154E067-2131
chr135336140353361466E0672118
chr135336154353361679E0672258
chr135331156253311680E068-47605
chr135331172953311779E068-47506
chr135334035853340446E068-18839
chr135335307353353386E068-5899
chr135335338953353775E068-5510
chr135335383853353909E068-5376
chr135335398653354083E068-5202
chr135335647653356558E068-2727
chr135335952153359571E068236
chr135335997253360161E068687
chr135336096853361249E0681683
chr135336140353361466E0682118
chr135336154353361679E0682258
chr135336181853361948E0682533
chr135340720053407264E06847915
chr135340750553407684E06848220
chr135340771053407945E06848425
chr135335307353353386E069-5899
chr135335338953353775E069-5510
chr135335383853353909E069-5376
chr135335398653354083E069-5202
chr135335647653356558E069-2727
chr135335669953357069E069-2216
chr135335710053357154E069-2131
chr135335716953357459E069-1826
chr135335870453359479E0690
chr135335952153359571E069236
chr135335997253360161E069687
chr135336096853361249E0691683
chr135336140353361466E0692118
chr135336154353361679E0692258
chr135336181853361948E0692533
chr135340750553407684E06948220
chr135340771053407945E06948425
chr135331182753311905E070-47380
chr135336947053369550E07010185
chr135336969053369787E07010405
chr135336987853370402E07010593
chr135337126753371665E07011982
chr135337170853371812E07012423
chr135337181853371868E07012533
chr135337195353372025E07012668
chr135337212653372206E07012841
chr135337282353372956E07013538
chr135335307353353386E071-5899
chr135335338953353775E071-5510
chr135335383853353909E071-5376
chr135335398653354083E071-5202
chr135335647653356558E071-2727
chr135335669953357069E071-2216
chr135335710053357154E071-2131
chr135335716953357459E071-1826
chr135335952153359571E071236
chr135335997253360161E071687
chr135336096853361249E0711683
chr135336140353361466E0712118
chr135336154353361679E0712258
chr135336181853361948E0712533
chr135336214953362472E0712864
chr135338314053383972E07123855
chr135335307353353386E072-5899
chr135335338953353775E072-5510
chr135335383853353909E072-5376
chr135335398653354083E072-5202
chr135335647653356558E072-2727
chr135335669953357069E072-2216
chr135335710053357154E072-2131
chr135335716953357459E072-1826
chr135335997253360161E072687
chr135336096853361249E0721683
chr135336140353361466E0722118
chr135336154353361679E0722258
chr135338037753380431E07221092
chr135338062853380678E07221343
chr135340720053407264E07247915
chr135340750553407684E07248220
chr135340771053407945E07248425
chr135335307353353386E074-5899
chr135335338953353775E074-5510
chr135335383853353909E074-5376
chr135335398653354083E074-5202
chr135335647653356558E074-2727
chr135335669953357069E074-2216
chr135335710053357154E074-2131
chr135335716953357459E074-1826
chr135335952153359571E074236
chr135335997253360161E074687
chr135336096853361249E0741683
chr135336140353361466E0742118
chr135336154353361679E0742258
chr135336181853361948E0742533
chr135336214953362472E0742864
chr135337990353379953E07420618
chr135338026553380373E07420980
chr135338037753380431E07421092
chr135338314053383972E07423855
chr135331063453310684E081-48601
chr135331102053311167E081-48118
chr135331123153311322E081-47963
chr135331475353314919E081-44366
chr135333229153332731E081-26554
chr135333274553332848E081-26437
chr135333972553339775E081-19510
chr135333983053340266E081-19019
chr135334035853340446E081-18839
chr135335307353353386E081-5899
chr135335338953353775E081-5510
chr135336947053369550E08110185
chr135336969053369787E08110405
chr135336987853370402E08110593
chr135337103853371128E08111753
chr135337126753371665E08111982
chr135337170853371812E08112423
chr135337181853371868E08112533
chr135337195353372025E08112668
chr135337212653372206E08112841
chr135337382653373886E08114541
chr135337388853373971E08114603
chr135337402753374375E08114742
chr135337438753374469E08115102
chr135337454453374761E08115259
chr135340771053407945E08148425
chr135331156253311680E082-47605
chr135331172953311779E082-47506
chr135331182753311905E082-47380
chr135332800653328448E082-30837
chr135333972553339775E082-19510
chr135333983053340266E082-19019
chr135334035853340446E082-18839
chr135336947053369550E08210185
chr135336969053369787E08210405
chr135336987853370402E08210593
chr135337103853371128E08211753
chr135337126753371665E08211982
chr135337170853371812E08212423
chr135337181853371868E08212533
chr135337195353372025E08212668
chr135337212653372206E08212841
chr135337372053373770E08214435
chr135340663753406733E08247352
chr135340720053407264E08247915
chr135340750553407684E08248220
chr135340771053407945E08248425









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr135331266053314519E067-44766
chr135331266053314519E068-44766
chr135331266053314519E069-44766
chr135331266053314519E072-44766
chr135331266053314519E073-44766
chr135331266053314519E074-44766
chr135331266053314519E082-44766