rs2361089

Homo sapiens
C>T
KANK1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0180 (5397/29902,GnomAD)
C==0174 (5093/29118,TOPMED)
C==0206 (1030/5008,1000G)
C==0209 (804/3854,ALSPAC)
C==0203 (753/3708,TWINSUK)
chr9:580868 (GRCh38.p7) (9p24.3)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.580868C>T
GRCh37.p13 chr 9NC_000009.11:g.580868C>T
KANK1 RefSeqGeneNG_016331.2:g.115575C>T

Gene: KANK1, KN motif and ankyrin repeat domains 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
KANK1 transcript variant 3NM_001256876.1:c.N/AIntron Variant
KANK1 transcript variant 4NM_001256877.1:c.N/AIntron Variant
KANK1 transcript variant 1NM_015158.3:c.N/AIntron Variant
KANK1 transcript variant 2NM_153186.4:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X2XM_005251411.2:c.N/AIntron Variant
KANK1 transcript variant X5XM_011517819.1:c.N/AIntron Variant
KANK1 transcript variant X6XM_011517820.1:c.N/AIntron Variant
KANK1 transcript variant X1XM_017014511.1:c.N/AIntron Variant
KANK1 transcript variant X4XM_017014513.1:c.N/AIntron Variant
KANK1 transcript variant X10XM_017014515.1:c.N/AIntron Variant
KANK1 transcript variant X13XM_017014518.1:c.N/AIntron Variant
KANK1 transcript variant X15XM_017014520.1:c.N/AIntron Variant
KANK1 transcript variant X17XM_017014522.1:c.N/AIntron Variant
KANK1 transcript variant X18XM_017014523.1:c.N/AIntron Variant
KANK1 transcript variant X29XM_017014528.1:c.N/AIntron Variant
KANK1 transcript variant X24XM_005251414.3:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X22XM_005251415.2:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X26XM_005251416.2:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X23XM_005251417.3:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X25XM_005251418.2:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X27XM_005251419.2:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X8XM_006716743.2:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X7XM_011517821.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X3XM_017014512.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X9XM_017014514.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X11XM_017014516.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X12XM_017014517.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X14XM_017014519.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X16XM_017014521.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X19XM_017014524.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X20XM_017014525.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X21XM_017014526.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X28XM_017014527.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X30XM_017014529.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X31XM_017014530.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X32XM_017014531.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X33XM_017014532.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X34XM_017014533.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X35XM_017014534.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X36XM_017014535.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X37XM_017014536.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X38XM_017014537.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X39XM_017014538.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X41XM_017014539.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X42XM_017014540.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X43XM_017014541.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X44XM_017014542.1:c.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X40XR_001746257.1:n.N/AGenic Upstream Transcript Variant
KANK1 transcript variant X45XR_001746258.1:n.N/AGenic Upstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.066T=0.934
1000GenomesAmericanSub694C=0.270T=0.730
1000GenomesEast AsianSub1008C=0.333T=0.667
1000GenomesEuropeSub1006C=0.216T=0.784
1000GenomesGlobalStudy-wide5008C=0.206T=0.794
1000GenomesSouth AsianSub978C=0.210T=0.790
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.209T=0.791
The Genome Aggregation DatabaseAfricanSub8704C=0.085T=0.915
The Genome Aggregation DatabaseAmericanSub836C=0.220T=0.780
The Genome Aggregation DatabaseEast AsianSub1620C=0.333T=0.667
The Genome Aggregation DatabaseEuropeSub18442C=0.207T=0.792
The Genome Aggregation DatabaseGlobalStudy-wide29902C=0.180T=0.819
The Genome Aggregation DatabaseOtherSub300C=0.340T=0.660
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.174T=0.825
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.203T=0.797
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs23610890.000154alcohol consumption23743675

eQTL of rs2361089 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2361089 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9531455531647E067-49221
chr9531769531905E067-48963
chr9531935532183E067-48685
chr9532466532799E067-48069
chr9532810533139E067-47729
chr9533317533523E067-47345
chr9533684533874E067-46994
chr9533985534531E067-46337
chr9534669534943E067-45925
chr9534972535361E067-45507
chr9535463535734E067-45134
chr9535743535849E067-45019
chr9537040537411E067-43457
chr9537498537586E067-43282
chr9537646537700E067-43168
chr9537748537933E067-42935
chr9538059538151E067-42717
chr9538240538389E067-42479
chr9544406544559E067-36309
chr9544637544773E067-36095
chr9544890545079E067-35789
chr9545245545352E067-35516
chr9545536545720E067-35148
chr9545724545829E067-35039
chr9546262547628E067-33240
chr9547741547856E067-33012
chr9547891548104E067-32764
chr9548193548243E067-32625
chr9549261549344E067-31524
chr9558445558593E067-22275
chr9560046560243E067-20625
chr9560348560446E067-20422
chr9560500560550E067-20318
chr9560701560789E067-20079
chr9560845561205E067-19663
chr9561468561924E067-18944
chr9562439562642E067-18226
chr9562912563844E067-17024
chr9563874564064E067-16804
chr9569032570658E067-10210
chr9570713570786E067-10082
chr9570925570999E067-9869
chr9571096571215E067-9653
chr9571221571532E067-9336
chr9571582572115E067-8753
chr9572958573162E067-7706
chr9573583574603E067-6265
chr9589168589389E0678300
chr9589520589584E0678652
chr9589600590159E0678732
chr9590160590507E0679292
chr9591279591734E06710411
chr9591999592597E06711131
chr9596434596484E06715566
chr9611236611286E06730368
chr9611471611521E06730603
chr9613610614810E06732742
chr9614921614971E06734053
chr9614997615051E06734129
chr9625970626215E06745102
chr9626378626418E06745510
chr9626554626692E06745686
chr9626731626962E06745863
chr9627032627454E06746164
chr9531088531237E068-49631
chr9531312531362E068-49506
chr9531455531647E068-49221
chr9531769531905E068-48963
chr9531935532183E068-48685
chr9532466532799E068-48069
chr9532810533139E068-47729
chr9533317533523E068-47345
chr9533684533874E068-46994
chr9533985534531E068-46337
chr9534669534943E068-45925
chr9534972535361E068-45507
chr9535463535734E068-45134
chr9535743535849E068-45019
chr9536038536078E068-44790
chr9536407536466E068-44402
chr9536679536748E068-44120
chr9536786536914E068-43954
chr9536921537020E068-43848
chr9537040537411E068-43457
chr9537498537586E068-43282
chr9537646537700E068-43168
chr9537748537933E068-42935
chr9544239544289E068-36579
chr9544406544559E068-36309
chr9544637544773E068-36095
chr9544890545079E068-35789
chr9545245545352E068-35516
chr9545536545720E068-35148
chr9545724545829E068-35039
chr9547891548104E068-32764
chr9548193548243E068-32625
chr9548384548463E068-32405
chr9552035552935E068-27933
chr9560845561205E068-19663
chr9561468561924E068-18944
chr9562439562642E068-18226
chr9564319564395E068-16473
chr9564787564837E068-16031
chr9570713570786E068-10082
chr9570925570999E068-9869
chr9571096571215E068-9653
chr9571221571532E068-9336
chr9571582572115E068-8753
chr9573583574603E068-6265
chr9574613574653E068-6215
chr9574754574818E068-6050
chr9579663579718E068-1150
chr9589168589389E0688300
chr9589520589584E0688652
chr9589600590159E0688732
chr9590160590507E0689292
chr9590828590904E0689960
chr9590966591151E06810098
chr9591279591734E06810411
chr9591999592597E06811131
chr9608530608829E06827662
chr9608920609108E06828052
chr9611236611286E06830368
chr9611471611521E06830603
chr9615882615993E06835014
chr9616662617026E06835794
chr9617361617943E06836493
chr9619108619185E06838240
chr9619431619591E06838563
chr9621214621897E06840346
chr9624987625545E06844119
chr9625570625630E06844702
chr9625687625737E06844819
chr9625760625951E06844892
chr9625970626215E06845102
chr9626378626418E06845510
chr9627032627454E06846164
chr9627620627910E06846752
chr9628077628139E06847209
chr9628176628272E06847308
chr9628389628472E06847521
chr9628480628617E06847612
chr9628640628731E06847772
chr9629215629404E06848347
chr9629442629570E06848574
chr9531088531237E069-49631
chr9531312531362E069-49506
chr9531455531647E069-49221
chr9531769531905E069-48963
chr9531935532183E069-48685
chr9532466532799E069-48069
chr9532810533139E069-47729
chr9533317533523E069-47345
chr9533684533874E069-46994
chr9533985534531E069-46337
chr9534669534943E069-45925
chr9534972535361E069-45507
chr9535743535849E069-45019
chr9536921537020E069-43848
chr9537040537411E069-43457
chr9537498537586E069-43282
chr9537646537700E069-43168
chr9537748537933E069-42935
chr9538059538151E069-42717
chr9538240538389E069-42479
chr9544239544289E069-36579
chr9544406544559E069-36309
chr9544637544773E069-36095
chr9544890545079E069-35789
chr9545245545352E069-35516
chr9545536545720E069-35148
chr9545724545829E069-35039
chr9546262547628E069-33240
chr9547741547856E069-33012
chr9547891548104E069-32764
chr9548193548243E069-32625
chr9549261549344E069-31524
chr9549370550149E069-30719
chr9552035552935E069-27933
chr9560348560446E069-20422
chr9560500560550E069-20318
chr9560701560789E069-20079
chr9560845561205E069-19663
chr9561468561924E069-18944
chr9562439562642E069-18226
chr9562912563844E069-17024
chr9563874564064E069-16804
chr9564319564395E069-16473
chr9564787564837E069-16031
chr9564856564906E069-15962
chr9564910564998E069-15870
chr9567283567458E069-13410
chr9567464567885E069-12983
chr9569032570658E069-10210
chr9570713570786E069-10082
chr9570925570999E069-9869
chr9571096571215E069-9653
chr9571221571532E069-9336
chr9571582572115E069-8753
chr9573583574603E069-6265
chr9588968589039E0698100
chr9589168589389E0698300
chr9589520589584E0698652
chr9589600590159E0698732
chr9590160590507E0699292
chr9590828590904E0699960
chr9590966591151E06910098
chr9591279591734E06910411
chr9596434596484E06915566
chr9608530608829E06927662
chr9608920609108E06928052
chr9610709610872E06929841
chr9610900610999E06930032
chr9611236611286E06930368
chr9613610614810E06932742
chr9614921614971E06934053
chr9614997615051E06934129
chr9619431619591E06938563
chr9621214621897E06940346
chr9624987625545E06944119
chr9625570625630E06944702
chr9625687625737E06944819
chr9625760625951E06944892
chr9625970626215E06945102
chr9626378626418E06945510
chr9626554626692E06945686
chr9626731626962E06945863
chr9627032627454E06946164
chr9627620627910E06946752
chr9628077628139E06947209
chr9628176628272E06947308
chr9628389628472E06947521
chr9628480628617E06947612
chr9628640628731E06947772
chr9629215629404E06948347
chr9534972535361E070-45507
chr9531088531237E071-49631
chr9531312531362E071-49506
chr9531455531647E071-49221
chr9531769531905E071-48963
chr9531935532183E071-48685
chr9532466532799E071-48069
chr9532810533139E071-47729
chr9533317533523E071-47345
chr9533684533874E071-46994
chr9533985534531E071-46337
chr9535463535734E071-45134
chr9535743535849E071-45019
chr9536038536078E071-44790
chr9536679536748E071-44120
chr9536786536914E071-43954
chr9536921537020E071-43848
chr9537040537411E071-43457
chr9537498537586E071-43282
chr9537646537700E071-43168
chr9537748537933E071-42935
chr9538059538151E071-42717
chr9538240538389E071-42479
chr9544239544289E071-36579
chr9544406544559E071-36309
chr9544637544773E071-36095
chr9544890545079E071-35789
chr9545245545352E071-35516
chr9545536545720E071-35148
chr9545724545829E071-35039
chr9549261549344E071-31524
chr9549370550149E071-30719
chr9551166551357E071-29511
chr9551636551714E071-29154
chr9552035552935E071-27933
chr9553489553539E071-27329
chr9557794558197E071-22671
chr9558445558593E071-22275
chr9559734560039E071-20829
chr9560046560243E071-20625
chr9560348560446E071-20422
chr9560500560550E071-20318
chr9560701560789E071-20079
chr9560845561205E071-19663
chr9561468561924E071-18944
chr9562439562642E071-18226
chr9564787564837E071-16031
chr9564856564906E071-15962
chr9564910564998E071-15870
chr9567283567458E071-13410
chr9567464567885E071-12983
chr9570713570786E071-10082
chr9570925570999E071-9869
chr9571096571215E071-9653
chr9571221571532E071-9336
chr9571582572115E071-8753
chr9572190572355E071-8513
chr9572408572499E071-8369
chr9572634572717E071-8151
chr9572958573162E071-7706
chr9573583574603E071-6265
chr9574613574653E071-6215
chr9574754574818E071-6050
chr9574933575460E071-5408
chr9578859578948E071-1920
chr9578963579071E071-1797
chr9588763588891E0717895
chr9588968589039E0718100
chr9589168589389E0718300
chr9589520589584E0718652
chr9589600590159E0718732
chr9591279591734E07110411
chr9591999592597E07111131
chr9592742592795E07111874
chr9592890592970E07112022
chr9596434596484E07115566
chr9608530608829E07127662
chr9608920609108E07128052
chr9610633610683E07129765
chr9610709610872E07129841
chr9610900610999E07130032
chr9613610614810E07132742
chr9614921614971E07134053
chr9614997615051E07134129
chr9615455615495E07134587
chr9615882615993E07135014
chr9616662617026E07135794
chr9618535618774E07137667
chr9618781618874E07137913
chr9619108619185E07138240
chr9619431619591E07138563
chr9621214621897E07140346
chr9624857624934E07143989
chr9624987625545E07144119
chr9625570625630E07144702
chr9625687625737E07144819
chr9625760625951E07144892
chr9625970626215E07145102
chr9626378626418E07145510
chr9626554626692E07145686
chr9626731626962E07145863
chr9627032627454E07146164
chr9531088531237E072-49631
chr9531312531362E072-49506
chr9531455531647E072-49221
chr9531769531905E072-48963
chr9531935532183E072-48685
chr9532466532799E072-48069
chr9532810533139E072-47729
chr9533317533523E072-47345
chr9533684533874E072-46994
chr9533985534531E072-46337
chr9534669534943E072-45925
chr9534972535361E072-45507
chr9535463535734E072-45134
chr9535743535849E072-45019
chr9537646537700E072-43168
chr9537748537933E072-42935
chr9538059538151E072-42717
chr9544890545079E072-35789
chr9545245545352E072-35516
chr9545536545720E072-35148
chr9545724545829E072-35039
chr9547891548104E072-32764
chr9549261549344E072-31524
chr9549370550149E072-30719
chr9552035552935E072-27933
chr9560845561205E072-19663
chr9561468561924E072-18944
chr9562439562642E072-18226
chr9562912563844E072-17024
chr9563874564064E072-16804
chr9564319564395E072-16473
chr9564787564837E072-16031
chr9564856564906E072-15962
chr9564910564998E072-15870
chr9569032570658E072-10210
chr9570713570786E072-10082
chr9570925570999E072-9869
chr9571096571215E072-9653
chr9571221571532E072-9336
chr9573583574603E072-6265
chr9574933575460E072-5408
chr9587598587704E0726730
chr9589168589389E0728300
chr9589520589584E0728652
chr9589600590159E0728732
chr9590160590507E0729292
chr9591279591734E07210411
chr9591999592597E07211131
chr9596434596484E07215566
chr9608530608829E07227662
chr9608920609108E07228052
chr9611236611286E07230368
chr9613610614810E07232742
chr9619431619591E07238563
chr9624857624934E07243989
chr9624987625545E07244119
chr9625570625630E07244702
chr9625687625737E07244819
chr9625760625951E07244892
chr9625970626215E07245102
chr9626378626418E07245510
chr9626554626692E07245686
chr9626731626962E07245863
chr9627032627454E07246164
chr9627620627910E07246752
chr9532810533139E073-47729
chr9533317533523E073-47345
chr9533684533874E073-46994
chr9534669534943E073-45925
chr9534972535361E073-45507
chr9535463535734E073-45134
chr9535743535849E073-45019
chr9536921537020E073-43848
chr9537040537411E073-43457
chr9544890545079E073-35789
chr9545245545352E073-35516
chr9545536545720E073-35148
chr9545724545829E073-35039
chr9546262547628E073-33240
chr9573583574603E073-6265
chr9589600590159E0738732
chr9613610614810E07332742
chr9615882615993E07335014
chr9616040616350E07335172
chr9621214621897E07340346
chr9624857624934E07343989
chr9624987625545E07344119
chr9625570625630E07344702
chr9625687625737E07344819
chr9625760625951E07344892
chr9625970626215E07345102
chr9626378626418E07345510
chr9626554626692E07345686
chr9626731626962E07345863
chr9627032627454E07346164
chr9531088531237E074-49631
chr9531312531362E074-49506
chr9531455531647E074-49221
chr9531769531905E074-48963
chr9531935532183E074-48685
chr9532466532799E074-48069
chr9532810533139E074-47729
chr9533317533523E074-47345
chr9533684533874E074-46994
chr9533985534531E074-46337
chr9534669534943E074-45925
chr9534972535361E074-45507
chr9535463535734E074-45134
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