rs2368446

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0169 (5072/29936,GnomAD)
T==0156 (4554/29118,TOPMED)
T==0206 (1034/5008,1000G)
T==0185 (713/3854,ALSPAC)
T==0185 (687/3708,TWINSUK)
chr2:183543235 (GRCh38.p7) (2q32.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.183543235T>C
GRCh37.p13 chr 2NC_000002.11:g.184407963T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.143C=0.857
1000GenomesAmericanSub694T=0.200C=0.800
1000GenomesEast AsianSub1008T=0.350C=0.650
1000GenomesEuropeSub1006T=0.170C=0.830
1000GenomesGlobalStudy-wide5008T=0.206C=0.794
1000GenomesSouth AsianSub978T=0.190C=0.810
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.185C=0.815
The Genome Aggregation DatabaseAfricanSub8720T=0.138C=0.862
The Genome Aggregation DatabaseAmericanSub838T=0.200C=0.800
The Genome Aggregation DatabaseEast AsianSub1606T=0.306C=0.694
The Genome Aggregation DatabaseEuropeSub18470T=0.171C=0.828
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.169C=0.830
The Genome Aggregation DatabaseOtherSub302T=0.120C=0.880
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.156C=0.843
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.185C=0.815
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs23684460.00053alcohol dependence20201924

eQTL of rs2368446 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2368446 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.