rs2369955

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0108 (3249/29970,GnomAD)
C=0083 (2425/29118,TOPMED)
C=0108 (540/5008,1000G)
C=0121 (466/3854,ALSPAC)
C=0124 (461/3708,TWINSUK)
chr3:132974744 (GRCh38.p7) (3q22.1)
AD
GWASdb2 | GWASCatalog
3   publication(s)
See rs on genome
18 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 3NC_000003.12:g.132974744A>C
GRCh37.p13 chr 3NC_000003.11:g.132693588A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.948C=0.052
1000GenomesAmericanSub694A=0.850C=0.150
1000GenomesEast AsianSub1008A=0.854C=0.146
1000GenomesEuropeSub1006A=0.882C=0.118
1000GenomesGlobalStudy-wide5008A=0.892C=0.108
1000GenomesSouth AsianSub978A=0.900C=0.100
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.879C=0.121
The Genome Aggregation DatabaseAfricanSub8726A=0.949C=0.051
The Genome Aggregation DatabaseAmericanSub836A=0.820C=0.180
The Genome Aggregation DatabaseEast AsianSub1616A=0.862C=0.138
The Genome Aggregation DatabaseEuropeSub18490A=0.870C=0.130
The Genome Aggregation DatabaseGlobalStudy-wide29970A=0.891C=0.108
The Genome Aggregation DatabaseOtherSub302A=0.930C=0.070
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.916C=0.083
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.876C=0.124
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry
25043041Neuropsychosocial profiles of current and future adolescent alcohol misusers.Whelan RNature

P-Value

SNP ID p-value Traits Study
rs23699550.000002alcoholism (heaviness of drinking)21529783
rs23699552.00E-06alcohol dependence21529783
rs23699550.00094alcohol dependence20201924

eQTL of rs2369955 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2369955 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr3132643765132643815E081-49773
chr3132643915132644756E081-48832
chr3132644922132644989E081-48599
chr3132645075132645243E081-48345
chr3132646843132647118E081-46470
chr3132715607132715685E08122019
chr3132716045132716162E08122457
chr3132716168132716231E08122580
chr3132716232132716333E08122644
chr3132716383132717057E08122795
chr3132717240132717295E08123652
chr3132735908132736122E08142320
chr3132736504132736687E08142916
chr3132716168132716231E08222580
chr3132716232132716333E08222644
chr3132716383132717057E08222795
chr3132741525132741591E08247937
chr3132741638132741696E08248050