rs2381642

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0405 (12116/29904,GnomAD)
G=0405 (11803/29118,TOPMED)
A==0499 (2500/5008,1000G)
chr9:7563692 (GRCh38.p7) (9p24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
64 Enhancers around
1 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.7563692A>G
GRCh37.p13 chr 9NC_000009.11:g.7563692A>G
GRCh38.p7 chr 9 alt locus HSCHR9_1_CTG1NW_003315928.1:g.149511A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.617G=0.383
1000GenomesAmericanSub694A=0.510G=0.490
1000GenomesEast AsianSub1008A=0.278G=0.722
1000GenomesEuropeSub1006A=0.633G=0.367
1000GenomesGlobalStudy-wide5008A=0.499G=0.501
1000GenomesSouth AsianSub978A=0.420G=0.580
The Genome Aggregation DatabaseAfricanSub8710A=0.593G=0.407
The Genome Aggregation DatabaseAmericanSub838A=0.490G=0.510
The Genome Aggregation DatabaseEast AsianSub1610A=0.294G=0.706
The Genome Aggregation DatabaseEuropeSub18444A=0.626G=0.373
The Genome Aggregation DatabaseGlobalStudy-wide29904A=0.594G=0.405
The Genome Aggregation DatabaseOtherSub302A=0.630G=0.370
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.594G=0.405
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs23816426.9E-05alcohol dependence24277619

eQTL of rs2381642 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2381642 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr975430847543203E067-20489
chr975602737560323E067-3369
chr975604857560535E067-3157
chr975606927560760E067-2932
chr975607967561313E067-2379
chr975613387561436E067-2256
chr975614577562013E067-1679
chr975621037562231E067-1461
chr975422017542636E068-21056
chr975426457543079E068-20613
chr975430847543203E068-20489
chr975435667543645E068-20047
chr975606927560760E068-2932
chr975607967561313E068-2379
chr975613387561436E068-2256
chr975614577562013E068-1679
chr975422017542636E069-21056
chr975426457543079E069-20613
chr975430847543203E069-20489
chr975435667543645E069-20047
chr975607967561313E069-2379
chr975613387561436E069-2256
chr975614577562013E069-1679
chr975492037549589E070-14103
chr975422017542636E071-21056
chr975430847543203E071-20489
chr975435667543645E071-20047
chr975602737560323E071-3369
chr975604857560535E071-3157
chr975606927560760E071-2932
chr975607967561313E071-2379
chr975613387561436E071-2256
chr975614577562013E071-1679
chr975430847543203E072-20489
chr975435667543645E072-20047
chr975606927560760E072-2932
chr975613387561436E072-2256
chr975614577562013E072-1679
chr975621037562231E072-1461
chr975422017542636E074-21056
chr975435667543645E074-20047
chr975606927560760E074-2932
chr975607967561313E074-2379
chr975613387561436E074-2256
chr975614577562013E074-1679
chr975230827523170E081-40522
chr975443777544484E081-19208
chr975448157544893E081-18799
chr975450207545070E081-18622
chr975453837545830E081-17862
chr975458847546032E081-17660
chr975461127546601E081-17091
chr975468567547080E081-16612
chr975789537579003E08115261
chr975790537579194E08115361
chr975792337579296E08115541
chr975793947579705E08115702
chr975799827580100E08116290
chr975801507580286E08116458
chr975805767580685E08116884
chr975448157544893E082-18799
chr975450207545070E082-18622
chr975453837545830E082-17862
chr975458847546032E082-17660









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr976068647606944E06843172