rs2386140

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0165 (4948/29930,GnomAD)
A==0153 (4473/29118,TOPMED)
A==0175 (878/5008,1000G)
A==0208 (802/3854,ALSPAC)
A==0205 (760/3708,TWINSUK)
chr9:136929170 (GRCh38.p7) (9q34.3)
AD
GWASdb2
1   publication(s)
See rs on genome
218 Enhancers around
27 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 9NC_000009.12:g.136929170A>G
GRCh37.p13 chr 9NC_000009.11:g.139823622A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.052G=0.948
1000GenomesAmericanSub694A=0.400G=0.600
1000GenomesEast AsianSub1008A=0.121G=0.879
1000GenomesEuropeSub1006A=0.192G=0.808
1000GenomesGlobalStudy-wide5008A=0.175G=0.825
1000GenomesSouth AsianSub978A=0.220G=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.208G=0.792
The Genome Aggregation DatabaseAfricanSub8720A=0.070G=0.930
The Genome Aggregation DatabaseAmericanSub836A=0.380G=0.620
The Genome Aggregation DatabaseEast AsianSub1620A=0.123G=0.877
The Genome Aggregation DatabaseEuropeSub18454A=0.204G=0.796
The Genome Aggregation DatabaseGlobalStudy-wide29930A=0.165G=0.834
The Genome Aggregation DatabaseOtherSub300A=0.180G=0.820
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.153G=0.846
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.205G=0.795
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs23861400.000749alcohol dependence21314694

eQTL of rs2386140 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
Chr9:139823622C9orf142ENSG00000148362.6A>G2.3000e-27-63248Cerebellum
Chr9:139823622C9orf142ENSG00000148362.6A>G2.8571e-13-63248Cerebellar_Hemisphere

meQTL of rs2386140 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr9139822692139823185E067-437
chr9139831166139831291E0677544
chr9139831314139831364E0677692
chr9139831685139831739E0678063
chr9139831912139831960E0678290
chr9139832039139832099E0678417
chr9139832148139832303E0678526
chr9139834527139835206E06710905
chr9139841423139842961E06717801
chr9139843141139843217E06719519
chr9139843400139843477E06719778
chr9139855584139856155E06731962
chr9139856243139856392E06732621
chr9139856495139856762E06732873
chr9139856936139857011E06733314
chr9139857247139857550E06733625
chr9139857556139857626E06733934
chr9139857648139857814E06734026
chr9139857921139858156E06734299
chr9139858196139858318E06734574
chr9139858567139858633E06734945
chr9139858825139859134E06735203
chr9139859210139859275E06735588
chr9139859393139859495E06735771
chr9139859543139859771E06735921
chr9139859858139859906E06736236
chr9139860018139860069E06736396
chr9139869297139869791E06745675
chr9139869795139870667E06746173
chr9139870709139870777E06747087
chr9139870845139870946E06747223
chr9139870984139871077E06747362
chr9139871188139871242E06747566
chr9139871310139871373E06747688
chr9139817455139817557E068-6065
chr9139833910139834241E06810288
chr9139834283139834380E06810661
chr9139834527139835206E06810905
chr9139841423139842961E06817801
chr9139843141139843217E06819519
chr9139843400139843477E06819778
chr9139845505139845662E06821883
chr9139855584139856155E06831962
chr9139856243139856392E06832621
chr9139857247139857550E06833625
chr9139857556139857626E06833934
chr9139857648139857814E06834026
chr9139857921139858156E06834299
chr9139858825139859134E06835203
chr9139869297139869791E06845675
chr9139869795139870667E06846173
chr9139870709139870777E06847087
chr9139870845139870946E06847223
chr9139870984139871077E06847362
chr9139871188139871242E06847566
chr9139871310139871373E06847688
chr9139779251139780035E069-43587
chr9139834527139835206E06910905
chr9139835280139835362E06911658
chr9139837462139837558E06913840
chr9139841423139842961E06917801
chr9139843400139843477E06919778
chr9139855130139855579E06931508
chr9139855584139856155E06931962
chr9139856243139856392E06932621
chr9139856495139856762E06932873
chr9139856936139857011E06933314
chr9139857247139857550E06933625
chr9139857556139857626E06933934
chr9139857648139857814E06934026
chr9139857921139858156E06934299
chr9139858196139858318E06934574
chr9139858567139858633E06934945
chr9139858825139859134E06935203
chr9139859210139859275E06935588
chr9139859393139859495E06935771
chr9139860208139860970E06936586
chr9139869795139870667E06946173
chr9139870709139870777E06947087
chr9139870845139870946E06947223
chr9139870984139871077E06947362
chr9139837306139837399E07013684
chr9139837462139837558E07013840
chr9139795492139797377E071-26245
chr9139833910139834241E07110288
chr9139834283139834380E07110661
chr9139834527139835206E07110905
chr9139835280139835362E07111658
chr9139835401139835882E07111779
chr9139836519139837290E07112897
chr9139837306139837399E07113684
chr9139841423139842961E07117801
chr9139843141139843217E07119519
chr9139843400139843477E07119778
chr9139855584139856155E07131962
chr9139856243139856392E07132621
chr9139856495139856762E07132873
chr9139856936139857011E07133314
chr9139857247139857550E07133625
chr9139857556139857626E07133934
chr9139857648139857814E07134026
chr9139857921139858156E07134299
chr9139858196139858318E07134574
chr9139858567139858633E07134945
chr9139858825139859134E07135203
chr9139860208139860970E07136586
chr9139869297139869791E07145675
chr9139869795139870667E07146173
chr9139870709139870777E07147087
chr9139870845139870946E07147223
chr9139870984139871077E07147362
chr9139871188139871242E07147566
chr9139871310139871373E07147688
chr9139810691139810817E072-12805
chr9139810835139810885E072-12737
chr9139810940139811075E072-12547
chr9139831166139831291E0727544
chr9139831314139831364E0727692
chr9139831685139831739E0728063
chr9139831912139831960E0728290
chr9139832039139832099E0728417
chr9139832148139832303E0728526
chr9139832341139832574E0728719
chr9139833910139834241E07210288
chr9139834283139834380E07210661
chr9139834527139835206E07210905
chr9139835280139835362E07211658
chr9139837462139837558E07213840
chr9139840062139841383E07216440
chr9139841423139842961E07217801
chr9139845505139845662E07221883
chr9139845698139845787E07222076
chr9139845872139846040E07222250
chr9139846153139846277E07222531
chr9139855130139855579E07231508
chr9139855584139856155E07231962
chr9139856243139856392E07232621
chr9139856495139856762E07232873
chr9139856936139857011E07233314
chr9139857247139857550E07233625
chr9139857556139857626E07233934
chr9139857648139857814E07234026
chr9139857921139858156E07234299
chr9139858196139858318E07234574
chr9139869297139869791E07245675
chr9139869795139870667E07246173
chr9139870709139870777E07247087
chr9139870845139870946E07247223
chr9139870984139871077E07247362
chr9139871188139871242E07247566
chr9139871310139871373E07247688
chr9139795492139797377E073-26245
chr9139822692139823185E073-437
chr9139831912139831960E0738290
chr9139832039139832099E0738417
chr9139832148139832303E0738526
chr9139832341139832574E0738719
chr9139834283139834380E07310661
chr9139834527139835206E07310905
chr9139835280139835362E07311658
chr9139835401139835882E07311779
chr9139836007139836083E07312385
chr9139836148139836223E07312526
chr9139836301139836476E07312679
chr9139836519139837290E07312897
chr9139837306139837399E07313684
chr9139837462139837558E07313840
chr9139841423139842961E07317801
chr9139843141139843217E07319519
chr9139843400139843477E07319778
chr9139845505139845662E07321883
chr9139845698139845787E07322076
chr9139845872139846040E07322250
chr9139846153139846277E07322531
chr9139853549139853622E07329927
chr9139853662139853731E07330040
chr9139853766139853922E07330144
chr9139855584139856155E07331962
chr9139856243139856392E07332621
chr9139856495139856762E07332873
chr9139856936139857011E07333314
chr9139857247139857550E07333625
chr9139858196139858318E07334574
chr9139863342139863427E07339720
chr9139863436139863480E07339814
chr9139863560139863633E07339938
chr9139867372139867441E07343750
chr9139867788139867893E07344166
chr9139869297139869791E07345675
chr9139869795139870667E07346173
chr9139870709139870777E07347087
chr9139870845139870946E07347223
chr9139870984139871077E07347362
chr9139871188139871242E07347566
chr9139871310139871373E07347688
chr9139834527139835206E07410905
chr9139835280139835362E07411658
chr9139837306139837399E07413684
chr9139837462139837558E07413840
chr9139841423139842961E07417801
chr9139843141139843217E07419519
chr9139843400139843477E07419778
chr9139855584139856155E07431962
chr9139856243139856392E07432621
chr9139857247139857550E07433625
chr9139857556139857626E07433934
chr9139857648139857814E07434026
chr9139857921139858156E07434299
chr9139858196139858318E07434574
chr9139869795139870667E07446173
chr9139870845139870946E07447223
chr9139870984139871077E07447362
chr9139871188139871242E07447566
chr9139871310139871373E07447688
chr9139779251139780035E081-43587
chr9139837306139837399E08113684
chr9139837462139837558E08113840
chr9139845505139845662E08121883









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr9139780262139782189E067-41433
chr9139837656139840035E06714034
chr9139843512139845441E06719890
chr9139780262139782189E068-41433
chr9139837656139840035E06814034
chr9139843512139845441E06819890
chr9139780262139782189E069-41433
chr9139837656139840035E06914034
chr9139843512139845441E06919890
chr9139780262139782189E070-41433
chr9139837656139840035E07014034
chr9139843512139845441E07019890
chr9139780262139782189E071-41433
chr9139837656139840035E07114034
chr9139843512139845441E07119890
chr9139780262139782189E072-41433
chr9139837656139840035E07214034
chr9139843512139845441E07219890
chr9139780262139782189E073-41433
chr9139837656139840035E07314034
chr9139843512139845441E07319890
chr9139780262139782189E074-41433
chr9139837656139840035E07414034
chr9139843512139845441E07419890
chr9139780262139782189E082-41433
chr9139837656139840035E08214034
chr9139843512139845441E08219890