rs2390798

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0246 (7337/29828,GnomAD)
A=0244 (7108/29118,TOPMED)
A=0336 (1685/5008,1000G)
A=0188 (725/3854,ALSPAC)
A=0185 (685/3708,TWINSUK)
chr4:125086041 (GRCh38.p7) (4q28.1)
AD
GWASdb2
1   publication(s)
See rs on genome
3 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.125086041G>A
GRCh37.p13 chr 4NC_000004.11:g.126007196G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.726A=0.274
1000GenomesAmericanSub694G=0.700A=0.300
1000GenomesEast AsianSub1008G=0.440A=0.560
1000GenomesEuropeSub1006G=0.779A=0.221
1000GenomesGlobalStudy-wide5008G=0.664A=0.336
1000GenomesSouth AsianSub978G=0.670A=0.330
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.812A=0.188
The Genome Aggregation DatabaseAfricanSub8676G=0.735A=0.265
The Genome Aggregation DatabaseAmericanSub834G=0.650A=0.350
The Genome Aggregation DatabaseEast AsianSub1602G=0.482A=0.518
The Genome Aggregation DatabaseEuropeSub18414G=0.791A=0.209
The Genome Aggregation DatabaseGlobalStudy-wide29828G=0.754A=0.246
The Genome Aggregation DatabaseOtherSub302G=0.760A=0.240
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.755A=0.244
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.815A=0.185
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs23907980.000164alcohol dependence20201924

eQTL of rs2390798 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2390798 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr4126045004126045157E07037808
chr4126012206126012591E0815010
chr4126012206126012591E0825010