rs2395670

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
A==0315 (9425/29884,GnomAD)
A==0300 (8758/29118,TOPMED)
A==0233 (1167/5008,1000G)
A==0339 (1308/3854,ALSPAC)
A==0322 (1195/3708,TWINSUK)
chr6:37115033 (GRCh38.p7) (6p21.2)
ND
GWASdb2
1   publication(s)
See rs on genome
92 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.37115033A>G
GRCh37.p13 chr 6NC_000006.11:g.37082809A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.282G=0.718
1000GenomesAmericanSub694A=0.270G=0.730
1000GenomesEast AsianSub1008A=0.094G=0.906
1000GenomesEuropeSub1006A=0.288G=0.712
1000GenomesGlobalStudy-wide5008A=0.233G=0.767
1000GenomesSouth AsianSub978A=0.220G=0.780
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.339G=0.661
The Genome Aggregation DatabaseAfricanSub8694A=0.281G=0.719
The Genome Aggregation DatabaseAmericanSub836A=0.310G=0.690
The Genome Aggregation DatabaseEast AsianSub1618A=0.121G=0.879
The Genome Aggregation DatabaseEuropeSub18434A=0.349G=0.650
The Genome Aggregation DatabaseGlobalStudy-wide29884A=0.315G=0.684
The Genome Aggregation DatabaseOtherSub302A=0.290G=0.710
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.300G=0.699
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.322G=0.678
PMID Title Author Journal
19268276Genome-wide association study of smoking initiation and current smoking.Vink JMAm J Hum Genet

P-Value

SNP ID p-value Traits Study
rs23956703.7E-05nicotine smoking19268276

eQTL of rs2395670 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2395670 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr63704515937045255E067-37554
chr63704530337045501E067-37308
chr63704551837046263E067-36546
chr63704671637046756E067-36053
chr63706964237069782E067-13027
chr63707179637071964E067-10845
chr63712862937129278E06745820
chr63704530337045501E068-37308
chr63704551837046263E068-36546
chr63706083337061006E068-21803
chr63706105437061198E068-21611
chr63706123837061382E068-21427
chr63706147437061572E068-21237
chr63706391137064238E068-18571
chr63707179637071964E068-10845
chr63712862937129278E06845820
chr63704515937045255E069-37554
chr63704530337045501E069-37308
chr63704551837046263E069-36546
chr63704671637046756E069-36053
chr63706890637069321E069-13488
chr63706964237069782E069-13027
chr63707179637071964E069-10845
chr63710182237102961E06919013
chr63705099237051788E070-31021
chr63706083337061006E070-21803
chr63706105437061198E070-21611
chr63706890637069321E070-13488
chr63706964237069782E070-13027
chr63707201037072092E070-10717
chr63707212737072221E070-10588
chr63707224537073047E070-9762
chr63707307437073203E070-9606
chr63709334137094648E07010532
chr63710182237102961E07019013
chr63710876137108871E07025952
chr63710887437110103E07026065
chr63711013437110371E07027325
chr63711207537112827E07029266
chr63704515937045255E071-37554
chr63704530337045501E071-37308
chr63704551837046263E071-36546
chr63706083337061006E071-21803
chr63706105437061198E071-21611
chr63706123837061382E071-21427
chr63706964237069782E071-13027
chr63706978337069911E071-12898
chr63709839137100104E07115582
chr63711013437110371E07127325
chr63712862937129278E07145820
chr63704530337045501E072-37308
chr63704551837046263E072-36546
chr63706229737062506E072-20303
chr63706266937062755E072-20054
chr63706332437063425E072-19384
chr63706978337069911E072-12898
chr63707179637071964E072-10845
chr63709839137100104E07215582
chr63704505637045106E073-37703
chr63704515937045255E073-37554
chr63704530337045501E073-37308
chr63704551837046263E073-36546
chr63706123837061382E073-21427
chr63706332437063425E073-19384
chr63706964237069782E073-13027
chr63707179637071964E073-10845
chr63710887437110103E07326065
chr63711013437110371E07327325
chr63704551837046263E074-36546
chr63706391137064238E074-18571
chr63706978337069911E074-12898
chr63704505637045106E081-37703
chr63704515937045255E081-37554
chr63704530337045501E081-37308
chr63704551837046263E081-36546
chr63706964237069782E081-13027
chr63707179637071964E081-10845
chr63709334137094648E08110532
chr63710476737106262E08121958
chr63710694837107627E08124139
chr63710803937108190E08125230
chr63710887437110103E08126065
chr63711013437110371E08127325
chr63704530337045501E082-37308
chr63706964237069782E082-13027
chr63706978337069911E082-12898
chr63707179637071964E082-10845
chr63710182237102961E08219013
chr63710694837107627E08224139
chr63710876137108871E08225952
chr63710887437110103E08226065
chr63711013437110371E08227325