SNP Detail Info-rs2404646

Organism: Homo sapiens

Alleles: C>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0143 (4276/29900,GnomAD)
G=0176 (5147/29118,TOPMED)
G=0169 (847/5008,1000G)
G=0072 (277/3854,ALSPAC)
G=0063 (233/3708,TWINSUK)

Position: chr4:135165126 (GRCh38.p7) (4q28.3)

Phenotype: ND

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.135165126C>G
GRCh37.p13 chr 4	NC_000004.11:g.136086281C>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.641	G=0.359
1000Genomes	American	Sub	694	C=0.930	G=0.070
1000Genomes	East Asian	Sub	1008	C=0.885	G=0.115
1000Genomes	Europe	Sub	1006	C=0.921	G=0.079
1000Genomes	Global	Study-wide	5008	C=0.831	G=0.169
1000Genomes	South Asian	Sub	978	C=0.870	G=0.130
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.928	G=0.072
The Genome Aggregation Database	African	Sub	8696	C=0.679	G=0.321
The Genome Aggregation Database	American	Sub	836	C=0.920	G=0.080
The Genome Aggregation Database	East Asian	Sub	1620	C=0.895	G=0.105
The Genome Aggregation Database	Europe	Sub	18446	C=0.934	G=0.065
The Genome Aggregation Database	Global	Study-wide	29900	C=0.857	G=0.143
The Genome Aggregation Database	Other	Sub	302	C=0.890	G=0.110
Trans-Omics for Precision Medicine	Global	Study-wide	29118	C=0.823	G=0.176
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.937	G=0.063

PMID	Title	Author	Journal
19268276	Genome-wide association study of smoking initiation and current smoking.	Vink JM	Am J Hum Genet

SNP ID	p-value	Traits	Study
rs2404646	6.48E-06	nicotine smoking	19268276

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs2404646