| Sequence Name | Change(s) |
|---|---|
| GRCh38.p7 chr 15 | NC_000015.10:g.40714325G>A |
| GRCh37.p13 chr 15 | NC_000015.9:g.41006523G>A |
| RAD51 RefSeqGene | NG_012120.1:g.24165G>A |
| Molecule type | Change | Amino acid[Codon] | SO Term |
|---|---|---|---|
| RAD51 transcript variant 4 | NM_001164269.1:c. | N/A | Intron Variant |
| RAD51 transcript variant 3 | NM_001164270.1:c. | N/A | Intron Variant |
| RAD51 transcript variant 1 | NM_002875.4:c. | N/A | Intron Variant |
| RAD51 transcript variant 2 | NM_133487.3:c. | N/A | Intron Variant |
| RAD51 transcript variant X2 | XM_006720626.3:c. | N/A | Intron Variant |
| RAD51 transcript variant X1 | XM_011521857.2:c. | N/A | Intron Variant |
| RAD51 transcript variant X5 | XM_011521858.2:c. | N/A | Intron Variant |
| RAD51 transcript variant X3 | XM_011521859.2:c. | N/A | Intron Variant |
| RAD51 transcript variant X4 | XM_011521860.2:c. | N/A | Intron Variant |
| RAD51 transcript variant X6 | XM_011521861.2:c. | N/A | Intron Variant |
| RAD51 transcript variant X7 | XM_011521862.2:c. | N/A | Intron Variant |
| Study | Population | Group | Sample # | Ref Allele | Alt Allele |
|---|---|---|---|---|---|
| 1000Genomes | African | Sub | 1322 | G=0.644 | A=0.356 |
| 1000Genomes | American | Sub | 694 | G=0.360 | A=0.640 |
| 1000Genomes | East Asian | Sub | 1008 | G=0.244 | A=0.756 |
| 1000Genomes | Europe | Sub | 1006 | G=0.504 | A=0.496 |
| 1000Genomes | Global | Study-wide | 5008 | G=0.440 | A=0.560 |
| 1000Genomes | South Asian | Sub | 978 | G=0.360 | A=0.640 |
| The Avon Longitudinal Study of Parents and Children | PARENT AND CHILD COHORT | Study-wide | 3854 | G=0.491 | A=0.509 |
| The Genome Aggregation Database | African | Sub | 8728 | G=0.628 | A=0.372 |
| The Genome Aggregation Database | American | Sub | 834 | G=0.330 | A=0.670 |
| The Genome Aggregation Database | East Asian | Sub | 1618 | G=0.229 | A=0.771 |
| The Genome Aggregation Database | Europe | Sub | 18448 | G=0.467 | A=0.532 |
| The Genome Aggregation Database | Global | Study-wide | 29930 | G=0.497 | A=0.502 |
| The Genome Aggregation Database | Other | Sub | 302 | G=0.450 | A=0.550 |
| Trans-Omics for Precision Medicine | Global | Study-wide | 29118 | G=0.552 | A=0.447 |
| UK 10K study - Twins | TWIN COHORT | Study-wide | 3708 | G=0.493 | A=0.507 |
| PMID | Title | Author | Journal |
|---|---|---|---|
| 18974064 | Genetic variants of BLM interact with RAD51 to increase breast cancer susceptibility. | Ding SL | Carcinogenesis |
| 21314694 | Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample. | Kendler KS | Alcohol Clin Exp Res |
| SNP ID | p-value | Traits | Study |
|---|---|---|---|
| rs2412546 | 0.000702 | alcohol dependence | 21314694 |
| Position (v37) | eGene | GeneID | Variant | p-value | TSS | Tissue |
|---|---|---|---|---|---|---|
| Chr15:41006523 | C15orf57 | ENSG00000128891.11 | G>A | 9.1956e-14 | 149267 | Cerebellum |
| Chr15:41006523 | ZFYVE19 | ENSG00000166140.13 | G>A | 4.9357e-13 | -92761 | Cerebellum |
| Chr15:41006523 | C15orf57 | ENSG00000128891.11 | G>A | 1.1352e-11 | 149267 | Hypothalamus |
| Chr15:41006523 | C15orf57 | ENSG00000128891.11 | G>A | 1.6265e-9 | 149267 | Substantia_nigra |
| Chr15:41006523 | C15orf57 | ENSG00000128891.11 | G>A | 3.6290e-8 | 149267 | Anterior_cingulate_cortex |
| Chr15:41006523 | C15orf57 | ENSG00000128891.11 | G>A | 4.3896e-11 | 149267 | Amygdala |
| Probe ID | Position | Gene | beta | p-value |
|---|---|---|---|---|
| cg25498107 | chr15:41100233 | DNAJC17|ZFYVE19 | 0.0670108037448819 | 1.0845e-9 |
| cg13045913 | chr15:41100308 | DNAJC17|ZFYVE19 | 0.0679502744039385 | 8.8044e-9 |
There is no significant Hi-C chromatin interaction data for this SNP.
| Chromosome | Start | End | Region | Distance ( -/+ : Up/Downstream ) |
|---|---|---|---|---|
| chr15 | 40985840 | 40985923 | E067 | -20600 |
| chr15 | 41044236 | 41044286 | E067 | 37713 |
| chr15 | 41044958 | 41045025 | E067 | 38435 |
| chr15 | 41045839 | 41046159 | E067 | 39316 |
| chr15 | 41055181 | 41055284 | E068 | 48658 |
| chr15 | 40985840 | 40985923 | E069 | -20600 |
| chr15 | 41039238 | 41039509 | E069 | 32715 |
| chr15 | 41039779 | 41040387 | E069 | 33256 |
| chr15 | 41044958 | 41045025 | E070 | 38435 |
| chr15 | 41045839 | 41046159 | E070 | 39316 |
| chr15 | 41054713 | 41054802 | E070 | 48190 |
| chr15 | 41054839 | 41054952 | E070 | 48316 |
| chr15 | 41054954 | 41055015 | E070 | 48431 |
| chr15 | 41055181 | 41055284 | E070 | 48658 |
| chr15 | 41039238 | 41039509 | E071 | 32715 |
| chr15 | 41039779 | 41040387 | E071 | 33256 |
| chr15 | 41040413 | 41040735 | E071 | 33890 |
| chr15 | 41045839 | 41046159 | E071 | 39316 |
| chr15 | 40985840 | 40985923 | E074 | -20600 |
| chr15 | 41055181 | 41055284 | E074 | 48658 |
| chr15 | 40985840 | 40985923 | E081 | -20600 |
| chr15 | 41045839 | 41046159 | E081 | 39316 |
| chr15 | 41054954 | 41055015 | E081 | 48431 |
| chr15 | 41055181 | 41055284 | E081 | 48658 |
| chr15 | 41054954 | 41055015 | E082 | 48431 |
| chr15 | 41055181 | 41055284 | E082 | 48658 |
| Chromosome | Start | End | Region | Distance(-/+:Up/Downstream) |
|---|---|---|---|---|
| chr15 | 40986365 | 40988129 | E067 | -18394 |
| chr15 | 41046627 | 41048322 | E067 | 40104 |
| chr15 | 40986365 | 40988129 | E068 | -18394 |
| chr15 | 41046627 | 41048322 | E068 | 40104 |
| chr15 | 40986365 | 40988129 | E069 | -18394 |
| chr15 | 41046627 | 41048322 | E069 | 40104 |
| chr15 | 40986365 | 40988129 | E070 | -18394 |
| chr15 | 40988208 | 40988258 | E070 | -18265 |
| chr15 | 40988482 | 40988564 | E070 | -17959 |
| chr15 | 41046627 | 41048322 | E070 | 40104 |
| chr15 | 40986365 | 40988129 | E071 | -18394 |
| chr15 | 41046627 | 41048322 | E071 | 40104 |
| chr15 | 40986365 | 40988129 | E072 | -18394 |
| chr15 | 41046627 | 41048322 | E072 | 40104 |
| chr15 | 40986365 | 40988129 | E073 | -18394 |
| chr15 | 41046627 | 41048322 | E073 | 40104 |
| chr15 | 40986365 | 40988129 | E074 | -18394 |
| chr15 | 41046627 | 41048322 | E074 | 40104 |
| chr15 | 40986365 | 40988129 | E081 | -18394 |
| chr15 | 41046627 | 41048322 | E081 | 40104 |
| chr15 | 40986365 | 40988129 | E082 | -18394 |
| chr15 | 40988208 | 40988258 | E082 | -18265 |
| chr15 | 40988482 | 40988564 | E082 | -17959 |
| chr15 | 41046627 | 41048322 | E082 | 40104 |