rs2414358

Homo sapiens
T>A
None
Check p-value
SNV (Single Nucleotide Variation)
T==0086 (2602/29936,GnomAD)
T==0135 (3947/29118,TOPMED)
T==0111 (558/5008,1000G)
T==0002 (6/3854,ALSPAC)
T==0001 (3/3708,TWINSUK)
chr15:54682301 (GRCh38.p7) (15q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.54682301T>A
GRCh37.p13 chr 15NC_000015.9:g.54974499T>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.373A=0.627
1000GenomesAmericanSub694T=0.020A=0.980
1000GenomesEast AsianSub1008T=0.006A=0.994
1000GenomesEuropeSub1006T=0.000A=1.000
1000GenomesGlobalStudy-wide5008T=0.111A=0.889
1000GenomesSouth AsianSub978T=0.040A=0.960
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.002A=0.998
The Genome Aggregation DatabaseAfricanSub8696T=0.295A=0.705
The Genome Aggregation DatabaseAmericanSub836T=0.010A=0.990
The Genome Aggregation DatabaseEast AsianSub1618T=0.001A=0.999
The Genome Aggregation DatabaseEuropeSub18484T=0.001A=0.998
The Genome Aggregation DatabaseGlobalStudy-wide29936T=0.086A=0.913
The Genome Aggregation DatabaseOtherSub302T=0.000A=1.000
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.135A=0.864
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.001A=0.999
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs24143580.000986alcohol dependence21314694

eQTL of rs2414358 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2414358 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr155498296254983045E0708463
chr155498333154983381E0708832