rs2414433

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0338 (10125/29928,GnomAD)
T==0486 (2436/5008,1000G)
T==0199 (768/3854,ALSPAC)
T==0193 (717/3708,TWINSUK)
chr15:55751991 (GRCh38.p7) (15q21.3)
AD
GWASdb2
1   publication(s)
See rs on genome
7 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.55751991T>C
GRCh37.p13 chr 15NC_000015.9:g.56044189T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.593C=0.407
1000GenomesAmericanSub694T=0.310C=0.690
1000GenomesEast AsianSub1008T=0.624C=0.376
1000GenomesEuropeSub1006T=0.226C=0.774
1000GenomesGlobalStudy-wide5008T=0.486C=0.514
1000GenomesSouth AsianSub978T=0.590C=0.410
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.199C=0.801
The Genome Aggregation DatabaseAfricanSub8688T=0.541C=0.459
The Genome Aggregation DatabaseAmericanSub836T=0.310C=0.690
The Genome Aggregation DatabaseEast AsianSub1610T=0.614C=0.386
The Genome Aggregation DatabaseEuropeSub18492T=0.220C=0.779
The Genome Aggregation DatabaseGlobalStudy-wide29928T=0.338C=0.661
The Genome Aggregation DatabaseOtherSub302T=0.280C=0.720
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.193C=0.807
PMID Title Author Journal
21529783A quantitative-trait genome-wide association study of alcoholism risk in the community: findings and implications.Heath ACBiol Psychiatry

P-Value

SNP ID p-value Traits Study
rs24144331.7E-05alcoholism (heaviness of drinking)21529783

eQTL of rs2414433 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2414433 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr155606065456060737E08116465
chr155606076856060899E08116579
chr155606099256061288E08116803
chr155606153556061603E08117346
chr155606172256061776E08117533
chr155606292756063105E08118738
chr155606312956063300E08118940

Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr155603301956036468E067-7721
chr155603301956036468E068-7721
chr155603301956036468E069-7721
chr155603301956036468E070-7721
chr155603301956036468E071-7721
chr155603301956036468E072-7721
chr155603301956036468E073-7721
chr155603301956036468E074-7721
chr155603301956036468E082-7721