rs2429239

Homo sapiens
A>C
None
Check p-value
SNV (Single Nucleotide Variation)
A==0337 (10105/29920,GnomAD)
A==0370 (10781/29118,TOPMED)
A==0324 (1625/5008,1000G)
A==0278 (1072/3854,ALSPAC)
A==0264 (978/3708,TWINSUK)
chr5:82440976 (GRCh38.p7) (5q14.2)
OD
GWASdb2
1   publication(s)
See rs on genome
5 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 5NC_000005.10:g.82440976A>C
GRCh37.p13 chr 5NC_000005.9:g.81736795A>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.564C=0.436
1000GenomesAmericanSub694A=0.270C=0.730
1000GenomesEast AsianSub1008A=0.277C=0.723
1000GenomesEuropeSub1006A=0.277C=0.723
1000GenomesGlobalStudy-wide5008A=0.324C=0.676
1000GenomesSouth AsianSub978A=0.130C=0.870
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.278C=0.722
The Genome Aggregation DatabaseAfricanSub8702A=0.510C=0.490
The Genome Aggregation DatabaseAmericanSub838A=0.240C=0.760
The Genome Aggregation DatabaseEast AsianSub1614A=0.289C=0.711
The Genome Aggregation DatabaseEuropeSub18464A=0.267C=0.732
The Genome Aggregation DatabaseGlobalStudy-wide29920A=0.337C=0.662
The Genome Aggregation DatabaseOtherSub302A=0.200C=0.800
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.370C=0.629
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.264C=0.736
PMID Title Author Journal
23183491Genome-wide association study identifies a potent locus associated with human opioid sensitivity.Nishizawa DMol Psychiatry

P-Value

SNP ID p-value Traits Study
rs24292394.9E-07Opioid sensitivity23183491

eQTL of rs2429239 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2429239 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr58169232081693304E068-43491
chr58176604981766252E07029254
chr58169232081693304E071-43491
chr58173190881732545E081-4250
chr58174063581740880E0813840