rs2465115

Homo sapiens
G>A / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0164 (4921/29904,GnomAD)
G==0160 (4677/29118,TOPMED)
G==0156 (779/5008,1000G)
chr10:90727078 (GRCh38.p7) (10q23.31)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.90727078G>A
GRCh38.p7 chr 10NC_000010.11:g.90727078G>T
GRCh37.p13 chr 10NC_000010.10:g.92486835G>A
GRCh37.p13 chr 10NC_000010.10:g.92486835G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.126T=0.874
1000GenomesAmericanSub694G=0.100T=0.900
1000GenomesEast AsianSub1008G=0.205T=0.795
1000GenomesEuropeSub1006G=0.167T=0.833
1000GenomesGlobalStudy-wide5008G=0.156T=0.844
1000GenomesSouth AsianSub978G=0.170T=0.830
The Genome Aggregation DatabaseAfricanSub8716G=0.134T=0.866
The Genome Aggregation DatabaseAmericanSub832G=0.080T=0.920
The Genome Aggregation DatabaseEast AsianSub1588G=0.233T=0.767
The Genome Aggregation DatabaseEuropeSub18466G=0.176T=0.823
The Genome Aggregation DatabaseGlobalStudy-wide29904G=0.164T=0.835
The Genome Aggregation DatabaseOtherSub302G=0.170T=0.830
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.160T=0.839
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs24651150.000495alcohol consumption (maxi-drinks)24277619

eQTL of rs2465115 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2465115 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr101622491216225016E08137737
chr101622491216225016E08237737