rs2472188

Homo sapiens
C>G
IL36RN : 3 Prime UTR Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0364 (10896/29900,GnomAD)
C==0328 (9557/29116,TOPMED)
C==0285 (1426/5008,1000G)
C==0414 (1597/3854,ALSPAC)
C==0393 (1456/3708,TWINSUK)
chr2:113063237 (GRCh38.p7) (2q14.1)
ND
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.113063237C>G
GRCh37.p13 chr 2NC_000002.11:g.113820814C>G
IL36RN RefSeqGene LRG_730

Gene: IL36RN, interleukin 36 receptor antagonist(plus strand)

Molecule type Change Amino acid[Codon] SO Term
IL36RN transcript variant 1NM_012275.2:c.N/A3 Prime UTR Variant
IL36RN transcript variant 2NM_173170.1:c.N/A3 Prime UTR Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.281G=0.719
1000GenomesAmericanSub694C=0.320G=0.680
1000GenomesEast AsianSub1008C=0.269G=0.731
1000GenomesEuropeSub1006C=0.379G=0.621
1000GenomesGlobalStudy-wide5008C=0.285G=0.715
1000GenomesSouth AsianSub978C=0.180G=0.820
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.414G=0.586
The Genome Aggregation DatabaseAfricanSub8698C=0.290G=0.710
The Genome Aggregation DatabaseAmericanSub838C=0.290G=0.710
The Genome Aggregation DatabaseEast AsianSub1618C=0.307G=0.693
The Genome Aggregation DatabaseEuropeSub18444C=0.409G=0.591
The Genome Aggregation DatabaseGlobalStudy-wide29900C=0.364G=0.635
The Genome Aggregation DatabaseOtherSub302C=0.320G=0.680
Trans-Omics for Precision MedicineGlobalStudy-wide29116C=0.328G=0.671
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.393G=0.607
PMID Title Author Journal
20158304A genomewide association study of nicotine and alcohol dependence in Australian and Dutch populations.Lind PATwin Res Hum Genet

P-Value

SNP ID p-value Traits Study
rs24721888.72E-06alcohol and nictotine co-dependence20158304

eQTL of rs2472188 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2472188 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.