rs2486416

Homo sapiens
C>T
UST : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
C==0072 (2184/29962,GnomAD)
C==0075 (2201/29118,TOPMED)
C==0129 (644/5008,1000G)
C==0055 (212/3854,ALSPAC)
C==0045 (166/3708,TWINSUK)
chr6:149014873 (GRCh38.p7) (6q25.1)
AD
GWASdb2
1   publication(s)
See rs on genome
91 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.149014873C>T
GRCh37.p13 chr 6NC_000006.11:g.149336009C>T

Gene: UST, uronyl 2-sulfotransferase(plus strand)

Molecule type Change Amino acid[Codon] SO Term
UST transcriptNM_005715.2:c.N/AIntron Variant
UST transcript variant X2XM_011535378.2:c.N/AGenic Downstream Transcript Variant
UST transcript variant X3XM_017010152.1:c.N/AGenic Downstream Transcript Variant
UST transcript variant X1XR_001743088.1:n.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.092T=0.908
1000GenomesAmericanSub694C=0.240T=0.760
1000GenomesEast AsianSub1008C=0.250T=0.750
1000GenomesEuropeSub1006C=0.037T=0.963
1000GenomesGlobalStudy-wide5008C=0.129T=0.871
1000GenomesSouth AsianSub978C=0.070T=0.930
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.055T=0.945
The Genome Aggregation DatabaseAfricanSub8716C=0.076T=0.924
The Genome Aggregation DatabaseAmericanSub838C=0.260T=0.740
The Genome Aggregation DatabaseEast AsianSub1614C=0.236T=0.764
The Genome Aggregation DatabaseEuropeSub18492C=0.048T=0.951
The Genome Aggregation DatabaseGlobalStudy-wide29962C=0.072T=0.927
The Genome Aggregation DatabaseOtherSub302C=0.090T=0.910
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.075T=0.924
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.045T=0.955
PMID Title Author Journal
21314694Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.Kendler KSAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs24864160.000691alcohol dependence21314694

eQTL of rs2486416 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2486416 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr6149334567149335019E067-990
chr6149335151149336852E0670
chr6149349570149350427E06713561
chr6149367803149368392E06731794
chr6149289235149289326E068-46683
chr6149289349149289761E068-46248
chr6149289811149291418E068-44591
chr6149334567149335019E068-990
chr6149335151149336852E0680
chr6149349570149350427E06813561
chr6149353118149354530E06817109
chr6149354569149354676E06818560
chr6149354965149355053E06818956
chr6149383112149383190E06847103
chr6149383215149383355E06847206
chr6149383377149383439E06847368
chr6149385000149385118E06848991
chr6149385146149385267E06849137
chr6149385270149385446E06849261
chr6149385594149385729E06849585
chr6149288137149289186E069-46823
chr6149289235149289326E069-46683
chr6149289349149289761E069-46248
chr6149311892149312125E069-23884
chr6149288137149289186E070-46823
chr6149289235149289326E070-46683
chr6149289349149289761E070-46248
chr6149310067149310145E070-25864
chr6149310225149310299E070-25710
chr6149310448149310516E070-25493
chr6149289349149289761E071-46248
chr6149310067149310145E071-25864
chr6149310225149310299E071-25710
chr6149310448149310516E071-25493
chr6149319954149320141E071-15868
chr6149320201149320322E071-15687
chr6149320374149320459E071-15550
chr6149320544149321806E071-14203
chr6149335151149336852E0710
chr6149341174149341226E0715165
chr6149353118149354530E07117109
chr6149354569149354676E07118560
chr6149354965149355053E07118956
chr6149366951149367037E07130942
chr6149367278149367683E07131269
chr6149384794149384993E07148785
chr6149289235149289326E072-46683
chr6149289349149289761E072-46248
chr6149353021149353105E07217012
chr6149353118149354530E07217109
chr6149288137149289186E073-46823
chr6149289235149289326E073-46683
chr6149289349149289761E073-46248
chr6149335151149336852E0730
chr6149365283149365427E07329274
chr6149365510149366166E07329501
chr6149288137149289186E074-46823
chr6149295023149295362E074-40647
chr6149295525149295610E074-40399
chr6149295647149295724E074-40285
chr6149295815149295865E074-40144
chr6149320544149321806E074-14203
chr6149349570149350427E07413561
chr6149353118149354530E07417109
chr6149367278149367683E07431269
chr6149380508149382989E07444499
chr6149383112149383190E07447103
chr6149383215149383355E07447206
chr6149383377149383439E07447368
chr6149383767149383817E07447758
chr6149383876149383969E07447867
chr6149384004149384058E07447995
chr6149384125149384175E07448116
chr6149384673149384757E07448664
chr6149384794149384993E07448785
chr6149385000149385118E07448991
chr6149385146149385267E07449137
chr6149385270149385446E07449261
chr6149385594149385729E07449585
chr6149288137149289186E081-46823
chr6149289235149289326E081-46683
chr6149289349149289761E081-46248
chr6149334164149334263E081-1746
chr6149334567149335019E081-990
chr6149335151149336852E0810
chr6149357657149357834E08121648
chr6149357977149358069E08121968
chr6149358101149358821E08122092
chr6149288137149289186E082-46823
chr6149334567149335019E082-990
chr6149335151149336852E0820