rs2504899

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0286 (8581/29940,GnomAD)
G==0295 (8590/29118,TOPMED)
G==0387 (1939/5008,1000G)
G==0196 (756/3854,ALSPAC)
G==0208 (772/3708,TWINSUK)
chr6:12531319 (GRCh38.p7) (6p24.1)
AD
GWASdb2
1   publication(s)
See rs on genome
21 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 6NC_000006.12:g.12531319G>T
GRCh37.p13 chr 6NC_000006.11:g.12531551G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.411T=0.589
1000GenomesAmericanSub694G=0.300T=0.700
1000GenomesEast AsianSub1008G=0.585T=0.415
1000GenomesEuropeSub1006G=0.229T=0.771
1000GenomesGlobalStudy-wide5008G=0.387T=0.613
1000GenomesSouth AsianSub978G=0.380T=0.620
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.196T=0.804
The Genome Aggregation DatabaseAfricanSub8714G=0.368T=0.632
The Genome Aggregation DatabaseAmericanSub836G=0.310T=0.690
The Genome Aggregation DatabaseEast AsianSub1614G=0.599T=0.401
The Genome Aggregation DatabaseEuropeSub18474G=0.220T=0.779
The Genome Aggregation DatabaseGlobalStudy-wide29940G=0.286T=0.713
The Genome Aggregation DatabaseOtherSub302G=0.250T=0.750
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.295T=0.705
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.208T=0.792
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs25048999.8E-05alcohol dependence21703634

eQTL of rs2504899 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2504899 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr61249836812498575E070-32976
chr61249878712498841E070-32710
chr61250585612505958E070-25593
chr61257061712570661E07039066
chr61257061712570661E07139066
chr61257078612570933E07139235
chr61257096212571090E07139411
chr61250585612505958E081-25593
chr61250602512506159E081-25392
chr61250636212506743E081-24808
chr61250687412506979E081-24572
chr61250703712507095E081-24456
chr61250735812507642E081-23909
chr61250811212508186E081-23365
chr61257061712570661E08139066
chr61257078612570933E08139235
chr61257096212571090E08139411
chr61257629712576581E08144746
chr61257665212577677E08145101
chr61250585612505958E082-25593
chr61250602512506159E082-25392