rs2526919

Homo sapiens
A>G
DPF3 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
A==0453 (13568/29896,GnomAD)
A==0444 (12944/29118,TOPMED)
A==0411 (2060/5008,1000G)
A==0465 (1793/3854,ALSPAC)
A==0470 (1741/3708,TWINSUK)
chr14:72641063 (GRCh38.p7) (14q24.2)
AD
GWASdb2
1   publication(s)
See rs on genome
119 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 14NC_000014.9:g.72641063A>G
GRCh37.p13 chr 14NC_000014.8:g.73107771A>G

Gene: DPF3, double PHD fingers 3(minus strand)

Molecule type Change Amino acid[Codon] SO Term
DPF3 transcript variant 2NM_001280542.1:c.N/AIntron Variant
DPF3 transcript variant 3NM_001280543.1:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant 4NM_001280544.1:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant 1NM_012074.4:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant X1XM_017021670.1:c.N/AIntron Variant
DPF3 transcript variant X3XM_017021672.1:c.N/AIntron Variant
DPF3 transcript variant X2XM_017021671.1:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant X4XM_017021673.1:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant X5XM_017021674.1:c.N/AGenic Downstream Transcript Variant
DPF3 transcript variant X5XM_017021675.1:c.N/AGenic Downstream Transcript Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.411G=0.589
1000GenomesAmericanSub694A=0.550G=0.450
1000GenomesEast AsianSub1008A=0.288G=0.712
1000GenomesEuropeSub1006A=0.443G=0.557
1000GenomesGlobalStudy-wide5008A=0.411G=0.589
1000GenomesSouth AsianSub978A=0.410G=0.590
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.465G=0.535
The Genome Aggregation DatabaseAfricanSub8696A=0.424G=0.576
The Genome Aggregation DatabaseAmericanSub836A=0.550G=0.450
The Genome Aggregation DatabaseEast AsianSub1618A=0.253G=0.747
The Genome Aggregation DatabaseEuropeSub18444A=0.482G=0.517
The Genome Aggregation DatabaseGlobalStudy-wide29896A=0.453G=0.546
The Genome Aggregation DatabaseOtherSub302A=0.380G=0.620
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.444G=0.555
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.470G=0.530
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs25269190.00074alcohol dependence20201924

eQTL of rs2526919 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2526919 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr147307949373079590E067-28181
chr147307972473079788E067-27983
chr147307982473079962E067-27809
chr147307999173080255E067-27516
chr147308184973081899E067-25872
chr147308198973082121E067-25650
chr147311310773113271E0675336
chr147311344773113507E0675676
chr147311361273113683E0675841
chr147311370573114216E0675934
chr147314568473146893E06737913
chr147308512873085381E068-22390
chr147311707773117342E0689306
chr147311744373117651E0689672
chr147311769873118145E0689927
chr147311818073118383E06810409
chr147311850873118558E06810737
chr147311857773118678E06810806
chr147311868373118756E06810912
chr147311878673118836E06811015
chr147311902073119140E06811249
chr147314568473146893E06837913
chr147310966873110600E0691897
chr147311067773110824E0692906
chr147311744373117651E0699672
chr147311769873118145E0699927
chr147311818073118383E06910409
chr147311850873118558E06910737
chr147311857773118678E06910806
chr147313119873131278E06923427
chr147313130373131406E06923532
chr147313146273131612E06923691
chr147314194073142118E06934169
chr147314217273142229E06934401
chr147314568473146893E06937913
chr147306422073064271E070-43500
chr147306461473064671E070-43100
chr147306470173064943E070-42828
chr147306499673065335E070-42436
chr147306539573065474E070-42297
chr147306560873065658E070-42113
chr147306641273067153E070-40618
chr147306722573067663E070-40108
chr147306769573067777E070-39994
chr147306784973067957E070-39814
chr147306798073068030E070-39741
chr147311769873118145E0709927
chr147311818073118383E07010409
chr147311850873118558E07010737
chr147311857773118678E07010806
chr147311868373118756E07010912
chr147311878673118836E07011015
chr147311902073119140E07011249
chr147314701373147063E07039242
chr147314716673147216E07039395
chr147314744773147545E07039676
chr147314755073147600E07039779
chr147310966873110600E0711897
chr147311687473117073E0719103
chr147311707773117342E0719306
chr147311769873118145E0719927
chr147311818073118383E07110409
chr147311850873118558E07110737
chr147311857773118678E07110806
chr147311868373118756E07110912
chr147311878673118836E07111015
chr147314568473146893E07137913
chr147314701373147063E07139242
chr147314716673147216E07139395
chr147314744773147545E07139676
chr147314755073147600E07139779
chr147307613673076261E072-31510
chr147310966873110600E0721897
chr147311067773110824E0722906
chr147311090573111005E0723134
chr147311818073118383E07210409
chr147311850873118558E07210737
chr147314568473146893E07237913
chr147314701373147063E07239242
chr147314716673147216E07239395
chr147307838373078574E073-29197
chr147307890873079000E073-28771
chr147307949373079590E073-28181
chr147307972473079788E073-27983
chr147307982473079962E073-27809
chr147307999173080255E073-27516
chr147308404373085094E073-22677
chr147311707773117342E0739306
chr147311744373117651E0739672
chr147314568473146893E07337913
chr147311707773117342E0749306
chr147311744373117651E0749672
chr147311769873118145E0749927
chr147311818073118383E07410409
chr147311850873118558E07410737
chr147311857773118678E07410806
chr147311868373118756E07410912
chr147311878673118836E07411015
chr147314176473141863E07433993
chr147314217273142229E07434401
chr147314568473146893E07437913
chr147314701373147063E07439242
chr147314716673147216E07439395
chr147314744773147545E07439676
chr147314755073147600E07439779
chr147314762373147984E07439852
chr147307949373079590E081-28181
chr147307972473079788E081-27983
chr147307982473079962E081-27809
chr147314473873144818E08136967
chr147314513173145626E08137360
chr147314568473146893E08137913
chr147314701373147063E08139242
chr147314716673147216E08139395
chr147314744773147545E08139676
chr147314755073147600E08139779
chr147314762373147984E08139852
chr147314701373147063E08239242
chr147314716673147216E08239395