rs2535483

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0395 (11815/29890,GnomAD)
T=0484 (14094/29118,TOPMED)
T=0457 (2288/5008,1000G)
T=0243 (936/3854,ALSPAC)
T=0244 (906/3708,TWINSUK)
chr15:97013682 (GRCh38.p7) (15q26.2)
AD
GWASdb2
1   publication(s)
See rs on genome
4 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.97013682C>T
GRCh37.p13 chr 15NC_000015.9:g.97556912C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.179T=0.821
1000GenomesAmericanSub694C=0.610T=0.390
1000GenomesEast AsianSub1008C=0.644T=0.356
1000GenomesEuropeSub1006C=0.760T=0.240
1000GenomesGlobalStudy-wide5008C=0.543T=0.457
1000GenomesSouth AsianSub978C=0.660T=0.340
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.757T=0.243
The Genome Aggregation DatabaseAfricanSub8702C=0.251T=0.749
The Genome Aggregation DatabaseAmericanSub836C=0.610T=0.390
The Genome Aggregation DatabaseEast AsianSub1596C=0.654T=0.346
The Genome Aggregation DatabaseEuropeSub18454C=0.765T=0.234
The Genome Aggregation DatabaseGlobalStudy-wide29890C=0.604T=0.395
The Genome Aggregation DatabaseOtherSub302C=0.700T=0.300
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.516T=0.484
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.756T=0.244
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs25354830.000563alcohol consumption (maxi-drinks)24277619

eQTL of rs2535483 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2535483 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr159751261497512664E070-44248
chr159751271697512795E070-44117
chr159751291897513272E070-43640
chr159751330597513405E081-43507