rs2556560

Homo sapiens
A>G
None
Check p-value
SNV (Single Nucleotide Variation)
G=0341 (10218/29920,GnomAD)
G=0296 (8623/29118,TOPMED)
G=0308 (1543/5008,1000G)
G=0408 (1574/3854,ALSPAC)
G=0415 (1538/3708,TWINSUK)
chr15:44529645 (GRCh38.p7) (15q21.1)
AD
GWASdb2
1   publication(s)
See rs on genome
98 Enhancers around
10 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 15NC_000015.10:g.44529645A>G
GRCh37.p13 chr 15NC_000015.9:g.44821843A>G

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322A=0.962G=0.038
1000GenomesAmericanSub694A=0.510G=0.490
1000GenomesEast AsianSub1008A=0.612G=0.388
1000GenomesEuropeSub1006A=0.585G=0.415
1000GenomesGlobalStudy-wide5008A=0.692G=0.308
1000GenomesSouth AsianSub978A=0.650G=0.350
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854A=0.592G=0.408
The Genome Aggregation DatabaseAfricanSub8716A=0.900G=0.100
The Genome Aggregation DatabaseAmericanSub838A=0.480G=0.520
The Genome Aggregation DatabaseEast AsianSub1600A=0.638G=0.362
The Genome Aggregation DatabaseEuropeSub18464A=0.556G=0.444
The Genome Aggregation DatabaseGlobalStudy-wide29920A=0.658G=0.341
The Genome Aggregation DatabaseOtherSub302A=0.570G=0.430
Trans-Omics for Precision MedicineGlobalStudy-wide29118A=0.703G=0.296
UK 10K study - TwinsTWIN COHORTStudy-wide3708A=0.585G=0.415
PMID Title Author Journal
21703634A meta-analysis of two genome-wide association studies identifies 3 new loci for alcohol dependence.Wang KSJ Psychiatr Res

P-Value

SNP ID p-value Traits Study
rs25565601.77E-05alcohol dependence21703634

eQTL of rs2556560 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2556560 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr154483370844834213E06711865
chr154483436144834540E06712518
chr154483458144834649E06712738
chr154483466244834760E06712819
chr154483479744834857E06712954
chr154483493744835051E06713094
chr154483546444835542E06713621
chr154483796144838104E06716118
chr154483814944838331E06716306
chr154483837344838570E06716530
chr154483864144838895E06716798
chr154484714744847506E06725304
chr154484756144847870E06725718
chr154483111244831211E0689269
chr154483341144833497E06811568
chr154483370844834213E06811865
chr154483436144834540E06812518
chr154483458144834649E06812738
chr154483466244834760E06812819
chr154483479744834857E06812954
chr154483493744835051E06813094
chr154483546444835542E06813621
chr154483796144838104E06816118
chr154483814944838331E06816306
chr154483837344838570E06816530
chr154483864144838895E06816798
chr154487060644871074E06848763
chr154481934344819840E069-2003
chr154481986844819918E069-1925
chr154481996844820048E069-1795
chr154482138744821480E069-363
chr154482151744821575E069-268
chr154482180744821861E0690
chr154482190844821980E06965
chr154482224844822502E069405
chr154482663444826697E0694791
chr154482677744826907E0694934
chr154482690844827027E0695065
chr154482715944827210E0695316
chr154482730944827423E0695466
chr154482750744827643E0695664
chr154483324344833344E06911400
chr154483341144833497E06911568
chr154483370844834213E06911865
chr154483436144834540E06912518
chr154483796144838104E06916118
chr154483814944838331E06916306
chr154483837344838570E06916530
chr154482677744826907E0704934
chr154482690844827027E0705065
chr154482715944827210E0705316
chr154482730944827423E0705466
chr154482750744827643E0705664
chr154482769744827754E0705854
chr154482750744827643E0715664
chr154482769744827754E0715854
chr154483436144834540E07112518
chr154483458144834649E07112738
chr154483466244834760E07112819
chr154483479744834857E07112954
chr154483493744835051E07113094
chr154483814944838331E07116306
chr154483837344838570E07116530
chr154483864144838895E07116798
chr154484714744847506E07125304
chr154484756144847870E07125718
chr154478142844782026E072-39817
chr154481906344819123E072-2720
chr154483370844834213E07211865
chr154483436144834540E07212518
chr154483458144834649E07212738
chr154483466244834760E07212819
chr154483479744834857E07212954
chr154483493744835051E07213094
chr154484714744847506E07225304
chr154484756144847870E07225718
chr154483281244832890E07310969
chr154483301244833140E07311169
chr154483324344833344E07311400
chr154483341144833497E07311568
chr154483370844834213E07311865
chr154483436144834540E07312518
chr154483458144834649E07312738
chr154483466244834760E07312819
chr154483479744834857E07312954
chr154483493744835051E07313094
chr154484714744847506E07325304
chr154484756144847870E07325718
chr154478142844782026E074-39817
chr154483111244831211E0749269
chr154482750744827643E0815664
chr154482769744827754E0815854
chr154482663444826697E0824791
chr154482677744826907E0824934
chr154482690844827027E0825065
chr154482715944827210E0825316
chr154483301244833140E08211169
chr154483324344833344E08211400










Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr154482814744830458E0676304
chr154482814744830458E0686304
chr154482814744830458E0696304
chr154482814744830458E0706304
chr154482814744830458E0716304
chr154482814744830458E0726304
chr154482814744830458E0736304
chr154482814744830458E0746304
chr154482814744830458E0816304
chr154482814744830458E0826304