SNP Detail Info-rs2606747

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 3	NC_000003.12:g.11333481T>G
GRCh38.p7 chr 3	NC_000003.12:g.11333481T>C
GRCh37.p13 chr 3	NC_000003.11:g.11374955T>G
GRCh37.p13 chr 3	NC_000003.11:g.11374955T>C

Gene: ATG7, autophagy related 7(plus strand)

Molecule type	Change	Amino acid[Codon]	SO Term
ATG7 transcript variant 2	NM_001136031.2:c.	N/A	Intron Variant
ATG7 transcript variant 3	NM_001144912.1:c.	N/A	Intron Variant
ATG7 transcript variant 1	NM_006395.2:c.	N/A	Intron Variant
ATG7 transcript variant X2	XM_006712931.3:c.	N/A	Intron Variant
ATG7 transcript variant X3	XM_006712932.3:c.	N/A	Intron Variant
ATG7 transcript variant X6	XM_006712933.3:c.	N/A	Intron Variant
ATG7 transcript variant X1	XM_011533277.2:c.	N/A	Intron Variant
ATG7 transcript variant X5	XM_011533278.2:c.	N/A	Intron Variant
ATG7 transcript variant X7	XM_011533279.2:c.	N/A	Intron Variant
ATG7 transcript variant X9	XM_011533280.2:c.	N/A	Intron Variant
ATG7 transcript variant X11	XM_011533281.2:c.	N/A	Intron Variant
ATG7 transcript variant X11	XM_011533282.2:c.	N/A	Intron Variant
ATG7 transcript variant X13	XM_011533283.2:c.	N/A	Intron Variant
ATG7 transcript variant X17	XM_011533284.2:c.	N/A	Intron Variant
ATG7 transcript variant X21	XM_011533285.2:c.	N/A	Intron Variant
ATG7 transcript variant X21	XM_011533286.2:c.	N/A	Intron Variant
ATG7 transcript variant X4	XM_017005542.1:c.	N/A	Intron Variant
ATG7 transcript variant X10	XM_017005543.1:c.	N/A	Intron Variant
ATG7 transcript variant X12	XM_017005544.1:c.	N/A	Intron Variant
ATG7 transcript variant X13	XM_017005545.1:c.	N/A	Intron Variant
ATG7 transcript variant X14	XM_017005546.1:c.	N/A	Intron Variant
ATG7 transcript variant X15	XM_017005547.1:c.	N/A	Intron Variant
ATG7 transcript variant X14	XM_017005548.1:c.	N/A	Intron Variant
ATG7 transcript variant X22	XM_017005549.1:c.	N/A	Intron Variant
ATG7 transcript variant X20	XM_017005550.1:c.	N/A	Intron Variant
ATG7 transcript variant X22	XM_017005551.1:c.	N/A	Intron Variant
ATG7 transcript variant X26	XM_017005552.1:c.	N/A	Intron Variant
ATG7 transcript variant X27	XM_017005553.1:c.	N/A	Intron Variant
ATG7 transcript variant X28	XM_017005554.1:c.	N/A	Intron Variant
ATG7 transcript variant X19	XR_001739980.1:n.	N/A	Intron Variant
ATG7 transcript variant X15	XR_940363.2:n.	N/A	Intron Variant

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.051	C=0.939
1000Genomes	American	Sub	694	T=0.110	C=0.89,
1000Genomes	East Asian	Sub	1008	T=0.000	C=1.000
1000Genomes	Europe	Sub	1006	T=0.200	C=0.800
1000Genomes	Global	Study-wide	5008	T=0.082	C=0.916
1000Genomes	South Asian	Sub	978	T=0.070	C=0.93,
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.170	C=0.830
The Genome Aggregation Database	African	Sub	8720	T=0.070	C=0.917
The Genome Aggregation Database	American	Sub	838	T=0.110	C=0.89,
The Genome Aggregation Database	East Asian	Sub	1622	T=0.001	C=0.999
The Genome Aggregation Database	Europe	Sub	18480	T=0.164	C=0.835
The Genome Aggregation Database	Global	Study-wide	29962	T=0.127	C=0.868
The Genome Aggregation Database	Other	Sub	302	T=0.280	C=0.72,
Trans-Omics for Precision Medicine	Global	Study-wide	29114	T=0.130	C=0.870
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.184	C=0.816

PMID	Title	Author	Journal
17158188	Novel genes identified in a high-density genome wide association study for nicotine dependence.	Bierut LJ	Hum Mol Genet

P-Value

SNP ID	p-value	Traits	Study
rs2606747	0.000667	nicotine dependence	17158188

eQTL of rs2606747 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs2606747 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs2606747

Genomic Coordinates

Gene: ATG7, autophagy related 7(plus strand)

Population Frequency

P-Value

eQTL of rs2606747 in Brain tissues (GTEx Analysis Release V7)

meQTL of rs2606747 in Fetal Brain

Genomic View

Chromatin Interaction