rs2612391

Homo sapiens
G>A / G>T
None
Check p-value
SNV (Single Nucleotide Variation)
G==0115 (3449/29994,GnomAD)
G==0109 (3181/29118,TOPMED)
G==0099 (494/5008,1000G)
G==0095 (366/3854,ALSPAC)
G==0094 (350/3708,TWINSUK)
chr18:75843162 (GRCh38.p7) (18q23)
AD
GWASdb2
1   publication(s)
See rs on genome
26 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 18NC_000018.10:g.75843162G>A
GRCh38.p7 chr 18NC_000018.10:g.75843162G>T
GRCh37.p13 chr 18NC_000018.9:g.73555117G>A
GRCh37.p13 chr 18NC_000018.9:g.73555117G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.118T=0.882
1000GenomesAmericanSub694G=0.130T=0.870
1000GenomesEast AsianSub1008G=0.071T=0.929
1000GenomesEuropeSub1006G=0.098T=0.902
1000GenomesGlobalStudy-wide5008G=0.099T=0.901
1000GenomesSouth AsianSub978G=0.080T=0.920
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.095T=0.905
The Genome Aggregation DatabaseAfricanSub8730G=0.118T=0.882
The Genome Aggregation DatabaseAmericanSub838G=0.150T=0.85,
The Genome Aggregation DatabaseEast AsianSub1622G=0.078T=0.922
The Genome Aggregation DatabaseEuropeSub18502G=0.116T=0.883
The Genome Aggregation DatabaseGlobalStudy-wide29994G=0.115T=0.885
The Genome Aggregation DatabaseOtherSub302G=0.080T=0.92,
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.109T=0.890
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.094T=0.906
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs26123910.00066alcohol dependence20201924

eQTL of rs2612391 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2612391 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr1864847436484973E067-44531
chr1864850356485330E067-44174
chr1864847436484973E068-44531
chr1864850356485330E068-44174
chr1864847436484973E069-44531
chr1864850356485330E069-44174
chr1864850356485330E070-44174
chr1865417896542064E07012285
chr1865421366542256E07012632
chr1865424486542632E07012944
chr1865426456542755E07013141
chr1865427646542830E07013260
chr1865429306543012E07013426
chr1865431026543192E07013598
chr1865432696543815E07013765
chr1865438726543939E07014368
chr1864847436484973E071-44531
chr1864850356485330E074-44174
chr1864948846494959E081-34545
chr1864951426496084E081-33420
chr1864961276496181E081-33323
chr1864962276496311E081-33193
chr1864964676496580E081-32924
chr1865587376559084E08129233
chr1865432696543815E08213765
chr1865438726543939E08214368