rs261446

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
C=0196 (5895/29978,GnomAD)
C=0173 (5053/29118,TOPMED)
C=0159 (796/5008,1000G)
C=0236 (909/3854,ALSPAC)
C=0246 (912/3708,TWINSUK)
chr13:81726846 (GRCh38.p7) (13q31.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 13NC_000013.11:g.81726846T>C
GRCh37.p13 chr 13NC_000013.10:g.82300981T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.904C=0.096
1000GenomesAmericanSub694T=0.780C=0.220
1000GenomesEast AsianSub1008T=0.926C=0.074
1000GenomesEuropeSub1006T=0.759C=0.241
1000GenomesGlobalStudy-wide5008T=0.841C=0.159
1000GenomesSouth AsianSub978T=0.800C=0.200
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.764C=0.236
The Genome Aggregation DatabaseAfricanSub8730T=0.884C=0.116
The Genome Aggregation DatabaseAmericanSub838T=0.820C=0.180
The Genome Aggregation DatabaseEast AsianSub1620T=0.919C=0.081
The Genome Aggregation DatabaseEuropeSub18488T=0.754C=0.245
The Genome Aggregation DatabaseGlobalStudy-wide29978T=0.803C=0.196
The Genome Aggregation DatabaseOtherSub302T=0.810C=0.190
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.826C=0.173
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.754C=0.246
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs2614460.000864alcohol dependence20201924

eQTL of rs261446 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs261446 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.