rs2615891

Homo sapiens
G>A
ATRNL1 : Intron Variant
Check p-value
SNV (Single Nucleotide Variation)
G==0459 (13746/29896,GnomAD)
A=0494 (14391/29118,TOPMED)
G==0455 (2279/5008,1000G)
G==0426 (1643/3854,ALSPAC)
G==0440 (1632/3708,TWINSUK)
chr10:115880805 (GRCh38.p7) (10q25.3)
ND
GWASdb2
1   publication(s)
See rs on genome
79 Enhancers around
9 Promoters around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 10NC_000010.11:g.115880805G>A
GRCh37.p13 chr 10 fix patch HG979_PATCHNW_004775432.1:g.854270G>A
GRCh37.p13 chr 10NC_000010.10:g.117640316G>A

Gene: ATRNL1, attractin like 1(plus strand)

Molecule type Change Amino acid[Codon] SO Term
ATRNL1 transcript variant 1NM_207303.4:c.N/AIntron Variant
ATRNL1 transcript variant 2NM_001276282.3:c.N/AGenic Downstream Transcript Variant
ATRNL1 transcript variant 3NR_074088.2:n.N/AGenic Downstream Transcript Variant
ATRNL1 transcript variant X3XM_011539587.1:c.N/AIntron Variant
ATRNL1 transcript variant X4XM_011539588.2:c.N/AIntron Variant
ATRNL1 transcript variant X7XM_011539590.2:c.N/AIntron Variant
ATRNL1 transcript variant X6XM_011539591.2:c.N/AIntron Variant
ATRNL1 transcript variant X10XM_017016037.1:c.N/AIntron Variant
ATRNL1 transcript variant X11XM_017016038.1:c.N/AIntron Variant
ATRNL1 transcript variant X12XM_017016039.1:c.N/AIntron Variant
ATRNL1 transcript variant X13XM_017016040.1:c.N/AIntron Variant
ATRNL1 transcript variant X5XM_011539589.2:c.N/AGenic Downstream Transcript Variant
ATRNL1 transcript variant X1XM_017016035.1:c.N/AGenic Downstream Transcript Variant
ATRNL1 transcript variant X8XM_017016036.1:c.N/AGenic Downstream Transcript Variant
ATRNL1 transcript variant X9XR_001747080.1:n.N/AIntron Variant
ATRNL1 transcript variant X2XR_945653.2:n.N/AIntron Variant

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.642A=0.358
1000GenomesAmericanSub694G=0.350A=0.650
1000GenomesEast AsianSub1008G=0.252A=0.748
1000GenomesEuropeSub1006G=0.420A=0.580
1000GenomesGlobalStudy-wide5008G=0.455A=0.545
1000GenomesSouth AsianSub978G=0.520A=0.480
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.426A=0.574
The Genome Aggregation DatabaseAfricanSub8702G=0.618A=0.382
The Genome Aggregation DatabaseAmericanSub838G=0.280A=0.720
The Genome Aggregation DatabaseEast AsianSub1616G=0.257A=0.743
The Genome Aggregation DatabaseEuropeSub18438G=0.410A=0.589
The Genome Aggregation DatabaseGlobalStudy-wide29896G=0.459A=0.540
The Genome Aggregation DatabaseOtherSub302G=0.460A=0.540
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.505A=0.494
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.440A=0.560
PMID Title Author Journal
17158188Novel genes identified in a high-density genome wide association study for nicotine dependence.Bierut LJHum Mol Genet

P-Value

SNP ID p-value Traits Study
rs26158910.000618nicotine dependence17158188

eQTL of rs2615891 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2615891 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr10829497829621E067-24649
chr10829628829701E067-24569
chr10891391891489E06737121
chr10891556892066E06737286
chr10892121892637E06737851
chr10902969903051E06748699
chr10903102903207E06748832
chr10903369903419E06749099
chr10836002836096E068-18174
chr10836133836235E068-18035
chr10852291852961E068-1309
chr10891391891489E06837121
chr10891556892066E06837286
chr10901751901920E06847481
chr10902365902911E06848095
chr10902969903051E06848699
chr10903102903207E06848832
chr10903369903419E06849099
chr10903477903517E06849207
chr10903537903661E06849267
chr10829497829621E069-24649
chr10829628829701E069-24569
chr10836002836096E069-18174
chr10836133836235E069-18035
chr10851653851867E069-2403
chr10851870851919E069-2351
chr10852018852175E069-2095
chr10852291852961E069-1309
chr10891391891489E06937121
chr10891556892066E06937286
chr10892121892637E06937851
chr10892650892755E06938380
chr10892756892821E06938486
chr10873590873670E07019320
chr10836002836096E071-18174
chr10836133836235E071-18035
chr10873590873670E07119320
chr10887440887490E07133170
chr10891391891489E07137121
chr10891556892066E07137286
chr10892121892637E07137851
chr10902365902911E07148095
chr10902969903051E07148699
chr10903102903207E07148832
chr10903369903419E07149099
chr10903477903517E07149207
chr10903537903661E07149267
chr10903839903919E07149569
chr10904112904183E07149842
chr10829225829301E072-24969
chr10829302829352E072-24918
chr10829497829621E072-24649
chr10829628829701E072-24569
chr10836002836096E072-18174
chr10836133836235E072-18035
chr10852018852175E072-2095
chr10892121892637E07237851
chr10902136902359E07247866
chr10902365902911E07248095
chr10902969903051E07248699
chr10903102903207E07248832
chr10829497829621E073-24649
chr10852018852175E073-2095
chr10852291852961E073-1309
chr10874105874145E07319835
chr10891556892066E07337286
chr10901751901920E07347481
chr10902136902359E07347866
chr10836002836096E074-18174
chr10836133836235E074-18035
chr10887440887490E07433170
chr10892121892637E07437851
chr10892650892755E07438380
chr10892756892821E07438486
chr10901751901920E07447481
chr10821532821638E081-32632
chr10829497829621E081-24649
chr10829628829701E081-24569
chr10831645831798E081-22472









Promoter Annotation (GRCh37.p13)

Chromosome Start End Region Distance(-/+:Up/Downstream)
chr10830405831219E067-23051
chr10830405831219E068-23051
chr10830405831219E069-23051
chr10830405831219E070-23051
chr10830405831219E071-23051
chr10830405831219E072-23051
chr10830405831219E073-23051
chr10830405831219E074-23051
chr10830405831219E082-23051