SNP Detail Info-rs263328

Organism: Homo sapiens

Alleles: T>G

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

G=0111 (3327/29952,GnomAD)
G=0130 (3784/29118,TOPMED)
G=0081 (405/5008,1000G)
G=0089 (344/3854,ALSPAC)
G=0094 (347/3708,TWINSUK)

Position: chr8:5722353 (GRCh38.p7) (8p23.2)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 8 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 8	NC_000008.11:g.5722353T>G
GRCh37.p13 chr 8	NC_000008.10:g.5579875T>G

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	T=0.787	G=0.213
1000Genomes	American	Sub	694	T=0.950	G=0.050
1000Genomes	East Asian	Sub	1008	T=1.000	G=0.000
1000Genomes	Europe	Sub	1006	T=0.928	G=0.072
1000Genomes	Global	Study-wide	5008	T=0.919	G=0.081
1000Genomes	South Asian	Sub	978	T=0.980	G=0.020
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	T=0.911	G=0.089
The Genome Aggregation Database	African	Sub	8722	T=0.814	G=0.186
The Genome Aggregation Database	American	Sub	836	T=0.940	G=0.060
The Genome Aggregation Database	East Asian	Sub	1620	T=0.999	G=0.001
The Genome Aggregation Database	Europe	Sub	18472	T=0.911	G=0.088
The Genome Aggregation Database	Global	Study-wide	29952	T=0.888	G=0.111
The Genome Aggregation Database	Other	Sub	302	T=0.920	G=0.080
Trans-Omics for Precision Medicine	Global	Study-wide	29118	T=0.870	G=0.130
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	T=0.906	G=0.094

PMID	Title	Author	Journal
20201924	Genome-wide association study of alcohol dependence implicates a region on chromosome 11.	Edenberg HJ	Alcohol Clin Exp Res

SNP ID	p-value	Traits	Study
rs263328	0.00021	alcohol dependence	20201924

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr8	5533892	5534065	E081	-45810
chr8	5534277	5534401	E081	-45474
chr8	5534410	5534570	E081	-45305
chr8	5534574	5534624	E081	-45251
chr8	5534672	5534726	E081	-45149
chr8	5616496	5616701	E081	36621
chr8	5616837	5616898	E081	36962
chr8	5617058	5617108	E081	37183

rs263328