rs2643902

Homo sapiens
T>C
None
Check p-value
SNV (Single Nucleotide Variation)
T==0291 (8713/29894,GnomAD)
T==0347 (10112/29118,TOPMED)
T==0403 (2018/5008,1000G)
T==0205 (790/3854,ALSPAC)
T==0219 (813/3708,TWINSUK)
chr1:2314000 (GRCh38.p7) (1p36.32)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 1NC_000001.11:g.2314000T>C
GRCh37.p13 chr 1NC_000001.10:g.2245439T>C

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322T=0.538C=0.462
1000GenomesAmericanSub694T=0.250C=0.750
1000GenomesEast AsianSub1008T=0.411C=0.589
1000GenomesEuropeSub1006T=0.232C=0.768
1000GenomesGlobalStudy-wide5008T=0.403C=0.597
1000GenomesSouth AsianSub978T=0.500C=0.500
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854T=0.205C=0.795
The Genome Aggregation DatabaseAfricanSub8712T=0.470C=0.530
The Genome Aggregation DatabaseAmericanSub838T=0.250C=0.750
The Genome Aggregation DatabaseEast AsianSub1612T=0.411C=0.589
The Genome Aggregation DatabaseEuropeSub18430T=0.198C=0.801
The Genome Aggregation DatabaseGlobalStudy-wide29894T=0.291C=0.708
The Genome Aggregation DatabaseOtherSub302T=0.300C=0.700
Trans-Omics for Precision MedicineGlobalStudy-wide29118T=0.347C=0.652
UK 10K study - TwinsTWIN COHORTStudy-wide3708T=0.219C=0.781
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs26439020.000377alcohol consumption (maxi-drinks)24277619

eQTL of rs2643902 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2643902 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr121967722196868E067-48571
chr121969502197028E067-48411
chr121970712197171E067-48268
chr121977922197904E067-47535
chr121980562198160E067-47279
chr121981962198384E067-47055
chr121983992198718E067-46721
chr121988592199316E067-46123
chr121998882199945E067-45494
chr121999782200018E067-45421
chr122001432200193E067-45246
chr122003312200381E067-45058
chr122006752200796E067-44643
chr122008642200961E067-44478
chr122009732201170E067-44269
chr122015222201576E067-43863
chr122015942201662E067-43777
chr122017092202460E067-42979
chr122026472203176E067-42263
chr122033162203524E067-41915
chr122035332203680E067-41759
chr122038322204147E067-41292
chr122041992204358E067-41081
chr122044102204460E067-40979
chr122045312204581E067-40858
chr122046772204853E067-40586
chr122050172205061E067-40378
chr122054272205499E067-39940
chr122056102205833E067-39606
chr122058652205962E067-39477
chr122060052206162E067-39277
chr122062632206379E067-39060
chr122064422206565E067-38874
chr122066702206796E067-38643
chr122072662207971E067-37468
chr122079762208112E067-37327
chr122092772209376E067-36063
chr122095662209823E067-35616
chr122098542210030E067-35409
chr122102172211564E067-33875
chr122115662211663E067-33776
chr122198642220163E067-25276
chr122202682220334E067-25105
chr122204792220542E067-24897
chr122206282220834E067-24605
chr122211192221343E067-24096
chr122214062221456E067-23983
chr122234862223537E067-21902
chr122235442223601E067-21838
chr122239592224016E067-21423
chr122240642224132E067-21307
chr122241972224515E067-20924
chr122256112225793E067-19646
chr122259272226169E067-19270
chr122299522230043E067-15396
chr122301102230215E067-15224
chr122303002230372E067-15067
chr122304042233096E067-12343
chr122331172233729E067-11710
chr122338472233970E067-11469
chr122340142234064E067-11375
chr122341162234360E067-11079
chr122360882236152E067-9287
chr122427982243602E067-1837
chr122436212247524E0670
chr122530932253224E0677654
chr122532622253389E0677823
chr122534552254782E0678016
chr121977922197904E068-47535
chr121980562198160E068-47279
chr121981962198384E068-47055
chr121983992198718E068-46721
chr121998882199945E068-45494
chr121999782200018E068-45421
chr122001432200193E068-45246
chr122003312200381E068-45058
chr122006752200796E068-44643
chr122008642200961E068-44478
chr122009732201170E068-44269
chr122015222201576E068-43863
chr122015942201662E068-43777
chr122017092202460E068-42979
chr122026472203176E068-42263
chr122033162203524E068-41915
chr122035332203680E068-41759
chr122038322204147E068-41292
chr122041992204358E068-41081
chr122044102204460E068-40979
chr122045312204581E068-40858
chr122046772204853E068-40586
chr122050172205061E068-40378
chr122054272205499E068-39940
chr122056102205833E068-39606
chr122058652205962E068-39477
chr122060052206162E068-39277
chr122062632206379E068-39060
chr122064422206565E068-38874
chr122066702206796E068-38643
chr122072662207971E068-37468
chr122079762208112E068-37327
chr122081582208369E068-37070
chr122092772209376E068-36063
chr122095662209823E068-35616
chr122098542210030E068-35409
chr122102172211564E068-33875
chr122115662211663E068-33776
chr122178292217920E068-27519
chr122179952218064E068-27375
chr122180882218142E068-27297
chr122182862218412E068-27027
chr122198642220163E068-25276
chr122202682220334E068-25105
chr122204792220542E068-24897
chr122206282220834E068-24605
chr122211192221343E068-24096
chr122234862223537E068-21902
chr122235442223601E068-21838
chr122239592224016E068-21423
chr122240642224132E068-21307
chr122241972224515E068-20924
chr122246552224788E068-20651
chr122248022224878E068-20561
chr122256112225793E068-19646
chr122259272226169E068-19270
chr122266502226853E068-18586
chr122270922227150E068-18289
chr122272472227389E068-18050
chr122295542229608E068-15831
chr122296262229676E068-15763
chr122297612229917E068-15522
chr122299522230043E068-15396
chr122301102230215E068-15224
chr122303002230372E068-15067
chr122304042233096E068-12343
chr122331172233729E068-11710
chr122338472233970E068-11469
chr122340142234064E068-11375
chr122341162234360E068-11079
chr122360882236152E068-9287
chr122362612237272E068-8167
chr122427982243602E068-1837
chr122436212247524E0680
chr122475452247627E0682106
chr122522262252293E0686787
chr122523772253055E0686938
chr122530932253224E0687654
chr122532622253389E0687823
chr122534552254782E0688016
chr121967722196868E069-48571
chr121969502197028E069-48411
chr121970712197171E069-48268
chr121975952197675E069-47764
chr121977922197904E069-47535
chr121980562198160E069-47279
chr121981962198384E069-47055
chr121988592199316E069-46123
chr121998882199945E069-45494
chr121999782200018E069-45421
chr122001432200193E069-45246
chr122003312200381E069-45058
chr122006752200796E069-44643
chr122008642200961E069-44478
chr122009732201170E069-44269
chr122015222201576E069-43863
chr122015942201662E069-43777
chr122017092202460E069-42979
chr122026472203176E069-42263
chr122033162203524E069-41915
chr122035332203680E069-41759
chr122038322204147E069-41292
chr122041992204358E069-41081
chr122054272205499E069-39940
chr122056102205833E069-39606
chr122058652205962E069-39477
chr122060052206162E069-39277
chr122062632206379E069-39060
chr122064422206565E069-38874
chr122066702206796E069-38643
chr122072662207971E069-37468
chr122079762208112E069-37327
chr122081582208369E069-37070
chr122083882208451E069-36988
chr122087552208893E069-36546
chr122092772209376E069-36063
chr122095662209823E069-35616
chr122098542210030E069-35409
chr122102172211564E069-33875
chr122198642220163E069-25276
chr122202682220334E069-25105
chr122204792220542E069-24897
chr122206282220834E069-24605
chr122211192221343E069-24096
chr122214062221456E069-23983
chr122234862223537E069-21902
chr122235442223601E069-21838
chr122239592224016E069-21423
chr122240642224132E069-21307
chr122241972224515E069-20924
chr122246552224788E069-20651
chr122248022224878E069-20561
chr122256112225793E069-19646
chr122259272226169E069-19270
chr122266502226853E069-18586
chr122270922227150E069-18289
chr122272472227389E069-18050
chr122274322227486E069-17953
chr122278232227967E069-17472
chr122279902228378E069-17061
chr122297612229917E069-15522
chr122299522230043E069-15396
chr122301102230215E069-15224
chr122303002230372E069-15067
chr122304042233096E069-12343
chr122331172233729E069-11710
chr122338472233970E069-11469
chr122340142234064E069-11375
chr122341162234360E069-11079
chr122349712235053E069-10386
chr122350732235147E069-10292
chr122354152235489E069-9950
chr122356152235665E069-9774
chr122356902235734E069-9705
chr122360882236152E069-9287
chr122415532241630E069-3809
chr122418602242158E069-3281
chr122427982243602E069-1837
chr122436212247524E0690
chr122523772253055E0696938
chr122530932253224E0697654
chr122532622253389E0697823
chr122534552254782E0698016
chr121967722196868E070-48571
chr121969502197028E070-48411
chr121970712197171E070-48268
chr121975952197675E070-47764
chr121977922197904E070-47535
chr121980562198160E070-47279
chr121981962198384E070-47055
chr121983992198718E070-46721
chr121988592199316E070-46123
chr121998882199945E070-45494
chr121999782200018E070-45421
chr122001432200193E070-45246
chr122003312200381E070-45058
chr122006752200796E070-44643
chr122008642200961E070-44478
chr122009732201170E070-44269
chr122015222201576E070-43863
chr122015942201662E070-43777
chr122041992204358E070-41081
chr122044102204460E070-40979
chr122045312204581E070-40858
chr122046772204853E070-40586
chr122050172205061E070-40378
chr122054272205499E070-39940
chr122056102205833E070-39606
chr122058652205962E070-39477
chr122060052206162E070-39277
chr122062632206379E070-39060
chr122064422206565E070-38874
chr122079762208112E070-37327
chr122081582208369E070-37070
chr122083882208451E070-36988
chr122092772209376E070-36063
chr122095662209823E070-35616
chr122098542210030E070-35409
chr122158032215906E070-29533
chr122160152216062E070-29377
chr122162812216331E070-29108
chr122165652216639E070-28800
chr122178292217920E070-27519
chr122179952218064E070-27375
chr122180882218142E070-27297
chr122182862218412E070-27027
chr122202682220334E070-25105
chr122204792220542E070-24897
chr122206282220834E070-24605
chr122211192221343E070-24096
chr122214062221456E070-23983
chr122234862223537E070-21902
chr122235442223601E070-21838
chr122239592224016E070-21423
chr122240642224132E070-21307
chr122241972224515E070-20924
chr122246552224788E070-20651
chr122248022224878E070-20561
chr122256112225793E070-19646
chr122259272226169E070-19270
chr122266502226853E070-18586
chr122270922227150E070-18289
chr122360882236152E070-9287
chr122427982243602E070-1837
chr122436212247524E0700
chr122475452247627E0702106
chr122476612247721E0702222
chr122478312248049E0702392
chr122523772253055E0706938
chr122530932253224E0707654
chr122532622253389E0707823
chr122609412261024E07015502
chr122613772261431E07015938
chr122615582261667E07016119
chr122617012261777E07016262
chr122620222262208E07016583
chr122622702262632E07016831
chr122626802262823E07017241
chr122629222263002E07017483
chr122672932267413E07021854
chr122674342267492E07021995
chr122676052267782E07022166
chr122799782280109E07034539
chr122801882280282E07034749
chr122808222280978E07035383
chr122812472281365E07035808
chr122814692281711E07036030
chr121975952197675E071-47764
chr121977922197904E071-47535
chr121980562198160E071-47279
chr121981962198384E071-47055
chr121983992198718E071-46721
chr121998882199945E071-45494
chr121999782200018E071-45421
chr122001432200193E071-45246
chr122003312200381E071-45058
chr122006752200796E071-44643
chr122008642200961E071-44478
chr122009732201170E071-44269
chr122015222201576E071-43863
chr122015942201662E071-43777
chr122017092202460E071-42979
chr122026472203176E071-42263
chr122033162203524E071-41915
chr122035332203680E071-41759
chr122038322204147E071-41292
chr122041992204358E071-41081
chr122044102204460E071-40979
chr122045312204581E071-40858
chr122046772204853E071-40586
chr122050172205061E071-40378
chr122054272205499E071-39940
chr122056102205833E071-39606
chr122058652205962E071-39477
chr122060052206162E071-39277
chr122072662207971E071-37468
chr122079762208112E071-37327
chr122081582208369E071-37070
chr122083882208451E071-36988
chr122092772209376E071-36063
chr122095662209823E071-35616
chr122098542210030E071-35409
chr122102172211564E071-33875
chr122115662211663E071-33776
chr122198642220163E071-25276
chr122202682220334E071-25105
chr122204792220542E071-24897
chr122206282220834E071-24605
chr122211192221343E071-24096
chr122214062221456E071-23983
chr122234862223537E071-21902
chr122235442223601E071-21838
chr122239592224016E071-21423
chr122240642224132E071-21307
chr122241972224515E071-20924
chr122246552224788E071-20651
chr122248022224878E071-20561
chr122256112225793E071-19646
chr122259272226169E071-19270
chr122279902228378E071-17061
chr122284992228613E071-16826
chr122292702229320E071-16119
chr122295542229608E071-15831
chr122296262229676E071-15763
chr122297612229917E071-15522
chr122299522230043E071-15396
chr122301102230215E071-15224
chr122303002230372E071-15067
chr122304042233096E071-12343
chr122331172233729E071-11710
chr122338472233970E071-11469
chr122340142234064E071-11375
chr122341162234360E071-11079
chr122349712235053E071-10386
chr122360882236152E071-9287
chr122415532241630E071-3809
chr122418602242158E071-3281
chr122425122242755E071-2684
chr122427982243602E071-1837
chr122436212247524E0710
chr122492532249345E0713814
chr122498942250065E0714455
chr122522262252293E0716787
chr122523772253055E0716938
chr122530932253224E0717654
chr122532622253389E0717823
chr122534552254782E0718016
chr122615582261667E07116119
chr122617012261777E07116262
chr122620222262208E07116583
chr122622702262632E07116831
chr122626802262823E07117241
chr121975952197675E072-47764
chr121977922197904E072-47535
chr121980562198160E072-47279
chr121981962198384E072-47055
chr121983992198718E072-46721
chr121988592199316E072-46123
chr121998882199945E072-45494
chr121999782200018E072-45421
chr122001432200193E072-45246
chr122003312200381E072-45058
chr122006752200796E072-44643
chr122008642200961E072-44478
chr122009732201170E072-44269
chr122015222201576E072-43863
chr122015942201662E072-43777
chr122017092202460E072-42979
chr122026472203176E072-42263
chr122033162203524E072-41915
chr122035332203680E072-41759
chr122038322204147E072-41292
chr122041992204358E072-41081
chr122044102204460E072-40979
chr122045312204581E072-40858
chr122046772204853E072-40586
chr122050172205061E072-40378
chr122054272205499E072-39940
chr122056102205833E072-39606
chr122058652205962E072-39477
chr122060052206162E072-39277
chr122062632206379E072-39060
chr122064422206565E072-38874
chr122066702206796E072-38643
chr122072662207971E072-37468
chr122079762208112E072-37327
chr122092772209376E072-36063
chr122095662209823E072-35616
chr122098542210030E072-35409
chr122102172211564E072-33875
chr122198642220163E072-25276
chr122202682220334E072-25105
chr122204792220542E072-24897
chr122206282220834E072-24605
chr122211192221343E072-24096
chr122214062221456E072-23983
chr122234862223537E072-21902
chr122235442223601E072-21838
chr122239592224016E072-21423
chr122240642224132E072-21307
chr122241972224515E072-20924
chr122246552224788E072-20651
chr122248022224878E072-20561
chr122256112225793E072-19646
chr122259272226169E072-19270
chr122266502226853E072-18586
chr122270922227150E072-18289
chr122272472227389E072-18050
chr122297612229917E072-15522
chr122299522230043E072-15396
chr122301102230215E072-15224
chr122303002230372E072-15067
chr122304042233096E072-12343
chr122331172233729E072-11710
chr122338472233970E072-11469
chr122340142234064E072-11375
chr122341162234360E072-11079
chr122349712235053E072-10386
chr122350732235147E072-10292
chr122354152235489E072-9950
chr122356152235665E072-9774
chr122356902235734E072-9705
chr122360882236152E072-9287
chr122418602242158E072-3281
chr122422042242293E072-3146
chr122423352242421E072-3018
chr122425122242755E072-2684
chr122427982243602E072-1837
chr122436212247524E0720
chr122523772253055E0726938
chr122530932253224E0727654
chr122532622253389E0727823
chr122534552254782E0728016
chr121977922197904E073-47535
chr121980562198160E073-47279
chr121981962198384E073-47055
chr121983992198718E073-46721
chr121988592199316E073-46123
chr121998882199945E073-45494
chr121999782200018E073-45421
chr122001432200193E073-45246
chr122003312200381E073-45058
chr122006752200796E073-44643
chr122008642200961E073-44478
chr122009732201170E073-44269
chr122015222201576E073-43863
chr122015942201662E073-43777
chr122017092202460E073-42979
chr122026472203176E073-42263
chr122033162203524E073-41915
chr122035332203680E073-41759
chr122038322204147E073-41292
chr122041992204358E073-41081
chr122044102204460E073-40979
chr122045312204581E073-40858
chr122046772204853E073-40586
chr122050172205061E073-40378
chr122054272205499E073-39940
chr122056102205833E073-39606
chr122058652205962E073-39477
chr122060052206162E073-39277
chr122062632206379E073-39060
chr122072662207971E073-37468
chr122079762208112E073-37327
chr122081582208369E073-37070
chr122083882208451E073-36988
chr122087552208893E073-36546
chr122092772209376E073-36063
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