SNP Detail Info-rs2660598

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0295 (8822/29888,GnomAD)
A=0302 (8811/29118,TOPMED)
A=0298 (1490/5008,1000G)
A=0338 (1302/3854,ALSPAC)
A=0356 (1320/3708,TWINSUK)

Position: chr4:62976344 (GRCh38.p7) (4q13.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 0 Enhancer around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 4	NC_000004.12:g.62976344G>A
GRCh37.p13 chr 4	NC_000004.11:g.63842062G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.782	A=0.218
1000Genomes	American	Sub	694	G=0.720	A=0.280
1000Genomes	East Asian	Sub	1008	G=0.688	A=0.312
1000Genomes	Europe	Sub	1006	G=0.677	A=0.323
1000Genomes	Global	Study-wide	5008	G=0.702	A=0.298
1000Genomes	South Asian	Sub	978	G=0.630	A=0.370
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.662	A=0.338
The Genome Aggregation Database	African	Sub	8708	G=0.762	A=0.238
The Genome Aggregation Database	American	Sub	834	G=0.730	A=0.270
The Genome Aggregation Database	East Asian	Sub	1594	G=0.730	A=0.270
The Genome Aggregation Database	Europe	Sub	18450	G=0.676	A=0.323
The Genome Aggregation Database	Global	Study-wide	29888	G=0.704	A=0.295
The Genome Aggregation Database	Other	Sub	302	G=0.580	A=0.420
Trans-Omics for Precision Medicine	Global	Study-wide	29118	G=0.697	A=0.302
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.644	A=0.356

PMID	Title	Author	Journal
24277619	ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.	Quillen EE	Am J Med Genet B Neuropsychiatr Genet

SNP ID	p-value	Traits	Study
rs2660598	0.000231	alcohol dependence	24277619

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

rs2660598