rs2660598

Homo sapiens
G>A
None
Check p-value
SNV (Single Nucleotide Variation)
A=0295 (8822/29888,GnomAD)
A=0302 (8811/29118,TOPMED)
A=0298 (1490/5008,1000G)
A=0338 (1302/3854,ALSPAC)
A=0356 (1320/3708,TWINSUK)
chr4:62976344 (GRCh38.p7) (4q13.1)
AD
GWASdb2
1   publication(s)
See rs on genome
0 Enhancer around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 4NC_000004.12:g.62976344G>A
GRCh37.p13 chr 4NC_000004.11:g.63842062G>A

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.782A=0.218
1000GenomesAmericanSub694G=0.720A=0.280
1000GenomesEast AsianSub1008G=0.688A=0.312
1000GenomesEuropeSub1006G=0.677A=0.323
1000GenomesGlobalStudy-wide5008G=0.702A=0.298
1000GenomesSouth AsianSub978G=0.630A=0.370
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.662A=0.338
The Genome Aggregation DatabaseAfricanSub8708G=0.762A=0.238
The Genome Aggregation DatabaseAmericanSub834G=0.730A=0.270
The Genome Aggregation DatabaseEast AsianSub1594G=0.730A=0.270
The Genome Aggregation DatabaseEuropeSub18450G=0.676A=0.323
The Genome Aggregation DatabaseGlobalStudy-wide29888G=0.704A=0.295
The Genome Aggregation DatabaseOtherSub302G=0.580A=0.420
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.697A=0.302
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.644A=0.356
PMID Title Author Journal
24277619ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample.Quillen EEAm J Med Genet B Neuropsychiatr Genet

P-Value

SNP ID p-value Traits Study
rs26605980.000231alcohol dependence24277619

eQTL of rs2660598 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2660598 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.