SNP Detail Info-rs2674041

Organism: Homo sapiens

Alleles: G>A

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

A=0301 (9021/29886,GnomAD)
A=0327 (9532/29116,TOPMED)
A=0373 (1866/5008,1000G)
A=0290 (1116/3854,ALSPAC)
A=0300 (1111/3708,TWINSUK)

Position: chr2:59530366 (GRCh38.p7) (2p16.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 13 Enhancers around

Promoter: 0 Promoter around

Sequence Name	Change(s)
GRCh38.p7 chr 2	NC_000002.12:g.59530366G>A
GRCh37.p13 chr 2	NC_000002.11:g.59757501G>A

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	G=0.651	A=0.349
1000Genomes	American	Sub	694	G=0.560	A=0.440
1000Genomes	East Asian	Sub	1008	G=0.486	A=0.514
1000Genomes	Europe	Sub	1006	G=0.710	A=0.290
1000Genomes	Global	Study-wide	5008	G=0.627	A=0.373
1000Genomes	South Asian	Sub	978	G=0.700	A=0.300
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	G=0.710	A=0.290
The Genome Aggregation Database	African	Sub	8700	G=0.674	A=0.326
The Genome Aggregation Database	American	Sub	838	G=0.540	A=0.460
The Genome Aggregation Database	East Asian	Sub	1618	G=0.481	A=0.519
The Genome Aggregation Database	Europe	Sub	18428	G=0.735	A=0.264
The Genome Aggregation Database	Global	Study-wide	29886	G=0.698	A=0.301
The Genome Aggregation Database	Other	Sub	302	G=0.710	A=0.290
Trans-Omics for Precision Medicine	Global	Study-wide	29116	G=0.672	A=0.327
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	G=0.700	A=0.300

PMID	Title	Author	Journal
23743675	A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.	Kapoor M	Hum Genet

SNP ID	p-value	Traits	Study
rs2674041	6.63E-05	alcohol consumption	23743675

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr2	59793570	59793733	E081	36069
chr2	59793775	59794244	E081	36274
chr2	59794294	59794429	E081	36793
chr2	59794482	59795096	E081	36981
chr2	59795318	59795414	E081	37817
chr2	59795566	59795892	E081	38065
chr2	59798318	59798751	E081	40817
chr2	59799462	59799668	E081	41961
chr2	59793570	59793733	E082	36069
chr2	59793775	59794244	E082	36274
chr2	59794294	59794429	E082	36793
chr2	59794482	59795096	E082	36981
chr2	59795318	59795414	E082	37817

rs2674041