rs2674046

Homo sapiens
C>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0290 (8673/29908,GnomAD)
T=0303 (8840/29118,TOPMED)
T=0353 (1769/5008,1000G)
T=0312 (1204/3854,ALSPAC)
T=0317 (1176/3708,TWINSUK)
chr2:59541006 (GRCh38.p7) (2p16.1)
AD
GWASdb2
1   publication(s)
See rs on genome
25 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 2NC_000002.12:g.59541006C>T
GRCh37.p13 chr 2NC_000002.11:g.59768141C>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322C=0.744T=0.256
1000GenomesAmericanSub694C=0.600T=0.400
1000GenomesEast AsianSub1008C=0.477T=0.523
1000GenomesEuropeSub1006C=0.687T=0.313
1000GenomesGlobalStudy-wide5008C=0.647T=0.353
1000GenomesSouth AsianSub978C=0.680T=0.320
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854C=0.688T=0.312
The Genome Aggregation DatabaseAfricanSub8712C=0.739T=0.261
The Genome Aggregation DatabaseAmericanSub836C=0.580T=0.420
The Genome Aggregation DatabaseEast AsianSub1612C=0.469T=0.531
The Genome Aggregation DatabaseEuropeSub18450C=0.724T=0.276
The Genome Aggregation DatabaseGlobalStudy-wide29908C=0.710T=0.290
The Genome Aggregation DatabaseOtherSub298C=0.670T=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118C=0.696T=0.303
UK 10K study - TwinsTWIN COHORTStudy-wide3708C=0.683T=0.317
PMID Title Author Journal
23743675A meta-analysis of two genome-wide association studies to identify novel loci for maximum number of alcoholic drinks.Kapoor MHum Genet

P-Value

SNP ID p-value Traits Study
rs26740465.61E-05alcohol consumption23743675

eQTL of rs2674046 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2674046 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr25981223659812346E07044095
chr25981267359813110E07044532
chr25981330659813694E07045165
chr25981267359813110E07144532
chr25981267359813110E07244532
chr25981267359813110E07444532
chr25979357059793733E08125429
chr25979377559794244E08125634
chr25979429459794429E08126153
chr25979448259795096E08126341
chr25979531859795414E08127177
chr25979556659795892E08127425
chr25979831859798751E08130177
chr25979946259799668E08131321
chr25981267359813110E08144532
chr25979357059793733E08225429
chr25979377559794244E08225634
chr25979429459794429E08226153
chr25979448259795096E08226341
chr25979531859795414E08227177
chr25981223659812346E08244095
chr25981267359813110E08244532
chr25981330659813694E08245165
chr25981540359815727E08247262
chr25981573359815897E08247592