rs2674959

Homo sapiens
G>T
None
Check p-value
SNV (Single Nucleotide Variation)
T=0320 (9569/29850,GnomAD)
T=0343 (9993/29118,TOPMED)
T=0285 (1428/5008,1000G)
T=0361 (1393/3854,ALSPAC)
T=0379 (1405/3708,TWINSUK)
chr17:13211937 (GRCh38.p7) (17p12)
AD
GWASdb2
1   publication(s)
See rs on genome
2 Enhancers around
0 Promoter around

Genomic Coordinates

Sequence Name Change(s)
GRCh38.p7 chr 17NC_000017.11:g.13211937G>T
GRCh37.p13 chr 17NC_000017.10:g.13115254G>T

Population Frequency

Study Population Group Sample # Ref Allele Alt Allele
1000GenomesAfricanSub1322G=0.680T=0.320
1000GenomesAmericanSub694G=0.700T=0.300
1000GenomesEast AsianSub1008G=0.829T=0.171
1000GenomesEuropeSub1006G=0.651T=0.349
1000GenomesGlobalStudy-wide5008G=0.715T=0.285
1000GenomesSouth AsianSub978G=0.720T=0.280
The Avon Longitudinal Study of Parents and ChildrenPARENT AND CHILD COHORTStudy-wide3854G=0.639T=0.361
The Genome Aggregation DatabaseAfricanSub8704G=0.698T=0.302
The Genome Aggregation DatabaseAmericanSub832G=0.770T=0.230
The Genome Aggregation DatabaseEast AsianSub1600G=0.829T=0.171
The Genome Aggregation DatabaseEuropeSub18412G=0.654T=0.345
The Genome Aggregation DatabaseGlobalStudy-wide29850G=0.679T=0.320
The Genome Aggregation DatabaseOtherSub302G=0.670T=0.330
Trans-Omics for Precision MedicineGlobalStudy-wide29118G=0.656T=0.343
UK 10K study - TwinsTWIN COHORTStudy-wide3708G=0.621T=0.379
PMID Title Author Journal
20201924Genome-wide association study of alcohol dependence implicates a region on chromosome 11.Edenberg HJAlcohol Clin Exp Res

P-Value

SNP ID p-value Traits Study
rs26749590.000816alcohol dependence20201924

eQTL of rs2674959 in Brain tissues (GTEx Analysis Release V7)

Position (v37) eGene GeneID Variant p-value TSS Tissue
There is no eQTL annotation for this SNP

meQTL of rs2674959 in Fetal Brain

Probe ID Position Gene beta p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome Start End Region Distance ( -/+ : Up/Downstream )
chr171312612113126282E07010867
chr171312628513126676E07011031