rs26913

Organism: Homo sapiens

Alleles: C>T

Gene : Feature

None

p-value: Check p-value

Variation Type: SNV (Single Nucleotide Variation)

Frequency:

C==0331 (9909/29924,GnomAD)
C==0296 (1484/5008,1000G)
C==0430 (1656/3854,ALSPAC)
C==0421 (1561/3708,TWINSUK)

Position: chr5:61634155 (GRCh38.p7) (5q12.1)

Phenotype: AD

Dataset:

GWASdb2

Publications: 1 publication(s)

Genomic View: See rs on genome

Enhancer: 398 Enhancers around

Promoter: 13 Promoters around

Variant Details Frequency Publications p-values eSNP meSNP

Genomic Coordinates

Sequence Name	Change(s)
GRCh38.p7 chr 5	NC_000005.10:g.61634155C>T
GRCh37.p13 chr 5	NC_000005.9:g.60929982C>T

Population Frequency

Study	Population	Group	Sample #	Ref Allele	Alt Allele
1000Genomes	African	Sub	1322	C=0.108	T=0.892
1000Genomes	American	Sub	694	C=0.420	T=0.580
1000Genomes	East Asian	Sub	1008	C=0.271	T=0.729
1000Genomes	Europe	Sub	1006	C=0.391	T=0.609
1000Genomes	Global	Study-wide	5008	C=0.296	T=0.704
1000Genomes	South Asian	Sub	978	C=0.390	T=0.610
The Avon Longitudinal Study of Parents and Children	PARENT AND CHILD COHORT	Study-wide	3854	C=0.430	T=0.570
The Genome Aggregation Database	African	Sub	8716	C=0.147	T=0.853
The Genome Aggregation Database	American	Sub	838	C=0.480	T=0.520
The Genome Aggregation Database	East Asian	Sub	1606	C=0.277	T=0.723
The Genome Aggregation Database	Europe	Sub	18462	C=0.413	T=0.586
The Genome Aggregation Database	Global	Study-wide	29924	C=0.331	T=0.668
The Genome Aggregation Database	Other	Sub	302	C=0.480	T=0.520
UK 10K study - Twins	TWIN COHORT	Study-wide	3708	C=0.421	T=0.579

PMID	Title	Author	Journal
21314694	Genomewide association analysis of symptoms of alcohol dependence in the molecular genetics of schizophrenia (MGS2) control sample.	Kendler KS	Alcohol Clin Exp Res

P-Value

SNP ID	p-value	Traits	Study
rs26913	0.000499	alcohol dependence	21314694

eQTL of rs26913 in Brain tissues (GTEx Analysis Release V7)

Position (v37)	eGene	GeneID	Variant	p-value	TSS	Tissue
There is no eQTL annotation for this SNP

meQTL of rs26913 in Fetal Brain

Probe ID	Position	Gene	beta	p-value
There is no meQTL annotation for this SNP

Genomic View

Chromatin Interaction

There is no significant Hi-C chromatin interaction data for this SNP.

Enhancer Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance ( -/+ : Up/Downstream )
chr5	60881907	60881995	E067	-47987
chr5	60882646	60882741	E067	-47241
chr5	60883088	60883214	E067	-46768
chr5	60895344	60895582	E067	-34400
chr5	60895707	60896178	E067	-33804
chr5	60896323	60896389	E067	-33593
chr5	60900512	60900748	E067	-29234
chr5	60901109	60901163	E067	-28819
chr5	60901454	60901517	E067	-28465
chr5	60905534	60906170	E067	-23812
chr5	60908461	60908595	E067	-21387
chr5	60908849	60908944	E067	-21038
chr5	60910571	60910729	E067	-19253
chr5	60913940	60914230	E067	-15752
chr5	60915208	60915406	E067	-14576
chr5	60916119	60916248	E067	-13734
chr5	60916538	60917006	E067	-12976
chr5	60917130	60917341	E067	-12641
chr5	60918100	60918304	E067	-11678
chr5	60919335	60919616	E067	-10366
chr5	60919662	60919761	E067	-10221
chr5	60920834	60920960	E067	-9022
chr5	60926869	60926985	E067	-2997
chr5	60927144	60927940	E067	-2042
chr5	60927979	60928178	E067	-1804
chr5	60928218	60928369	E067	-1613
chr5	60928477	60928822	E067	-1160
chr5	60928887	60929017	E067	-965
chr5	60931248	60931328	E067	1266
chr5	60931933	60932043	E067	1951
chr5	60932651	60932705	E067	2669
chr5	60935660	60935772	E067	5678
chr5	60936058	60936185	E067	6076
chr5	60936272	60936338	E067	6290
chr5	60936552	60936730	E067	6570
chr5	60946129	60946203	E067	16147
chr5	60954335	60955657	E067	24353
chr5	60962181	60962325	E067	32199
chr5	60963833	60963894	E067	33851
chr5	60968708	60969317	E067	38726
chr5	60969433	60969514	E067	39451
chr5	60969785	60969861	E067	39803
chr5	60970236	60970561	E067	40254
chr5	60970828	60970891	E067	40846
chr5	60970894	60971210	E067	40912
chr5	60971482	60971532	E067	41500
chr5	60881907	60881995	E068	-47987
chr5	60882646	60882741	E068	-47241
chr5	60883088	60883214	E068	-46768
chr5	60895344	60895582	E068	-34400
chr5	60895707	60896178	E068	-33804
chr5	60896323	60896389	E068	-33593
chr5	60899104	60899333	E068	-30649
chr5	60899447	60899592	E068	-30390
chr5	60900512	60900748	E068	-29234
chr5	60901109	60901163	E068	-28819
chr5	60901454	60901517	E068	-28465
chr5	60905534	60906170	E068	-23812
chr5	60908461	60908595	E068	-21387
chr5	60908849	60908944	E068	-21038
chr5	60910571	60910729	E068	-19253
chr5	60912971	60913142	E068	-16840
chr5	60913940	60914230	E068	-15752
chr5	60915208	60915406	E068	-14576
chr5	60916119	60916248	E068	-13734
chr5	60916538	60917006	E068	-12976
chr5	60917130	60917341	E068	-12641
chr5	60918100	60918304	E068	-11678
chr5	60919335	60919616	E068	-10366
chr5	60919662	60919761	E068	-10221
chr5	60920154	60920198	E068	-9784
chr5	60920582	60920642	E068	-9340
chr5	60926869	60926985	E068	-2997
chr5	60928218	60928369	E068	-1613
chr5	60928477	60928822	E068	-1160
chr5	60928887	60929017	E068	-965
chr5	60931248	60931328	E068	1266
chr5	60931933	60932043	E068	1951
chr5	60932651	60932705	E068	2669
chr5	60933482	60933692	E068	3500
chr5	60935660	60935772	E068	5678
chr5	60936058	60936185	E068	6076
chr5	60936272	60936338	E068	6290
chr5	60936552	60936730	E068	6570
chr5	60937908	60937972	E068	7926
chr5	60938111	60938277	E068	8129
chr5	60946129	60946203	E068	16147
chr5	60952888	60952938	E068	22906
chr5	60952982	60953059	E068	23000
chr5	60954335	60955657	E068	24353
chr5	60955990	60956044	E068	26008
chr5	60956416	60956487	E068	26434
chr5	60961931	60961981	E068	31949
chr5	60963480	60963718	E068	33498
chr5	60963833	60963894	E068	33851
chr5	60965462	60965614	E068	35480
chr5	60968451	60968501	E068	38469
chr5	60968708	60969317	E068	38726
chr5	60969433	60969514	E068	39451
chr5	60969785	60969861	E068	39803
chr5	60970236	60970561	E068	40254
chr5	60970828	60970891	E068	40846
chr5	60970894	60971210	E068	40912
chr5	60883088	60883214	E069	-46768
chr5	60894979	60895039	E069	-34943
chr5	60895047	60895087	E069	-34895
chr5	60895344	60895582	E069	-34400
chr5	60895707	60896178	E069	-33804
chr5	60896323	60896389	E069	-33593
chr5	60899447	60899592	E069	-30390
chr5	60900512	60900748	E069	-29234
chr5	60901109	60901163	E069	-28819
chr5	60901454	60901517	E069	-28465
chr5	60905534	60906170	E069	-23812
chr5	60908461	60908595	E069	-21387
chr5	60908849	60908944	E069	-21038
chr5	60910571	60910729	E069	-19253
chr5	60912971	60913142	E069	-16840
chr5	60913940	60914230	E069	-15752
chr5	60915208	60915406	E069	-14576
chr5	60916119	60916248	E069	-13734
chr5	60918100	60918304	E069	-11678
chr5	60919335	60919616	E069	-10366
chr5	60919662	60919761	E069	-10221
chr5	60920154	60920198	E069	-9784
chr5	60920582	60920642	E069	-9340
chr5	60926869	60926985	E069	-2997
chr5	60928218	60928369	E069	-1613
chr5	60928477	60928822	E069	-1160
chr5	60928887	60929017	E069	-965
chr5	60931248	60931328	E069	1266
chr5	60931933	60932043	E069	1951
chr5	60932651	60932705	E069	2669
chr5	60935660	60935772	E069	5678
chr5	60936058	60936185	E069	6076
chr5	60936272	60936338	E069	6290
chr5	60936552	60936730	E069	6570
chr5	60937908	60937972	E069	7926
chr5	60946129	60946203	E069	16147
chr5	60952982	60953059	E069	23000
chr5	60954335	60955657	E069	24353
chr5	60955990	60956044	E069	26008
chr5	60956416	60956487	E069	26434
chr5	60962181	60962325	E069	32199
chr5	60963480	60963718	E069	33498
chr5	60963833	60963894	E069	33851
chr5	60965462	60965614	E069	35480
chr5	60968451	60968501	E069	38469
chr5	60968708	60969317	E069	38726
chr5	60969433	60969514	E069	39451
chr5	60969785	60969861	E069	39803
chr5	60970236	60970561	E069	40254
chr5	60970828	60970891	E069	40846
chr5	60970894	60971210	E069	40912
chr5	60971482	60971532	E069	41500
chr5	60976131	60976242	E069	46149
chr5	60976286	60976336	E069	46304
chr5	60976380	60976477	E069	46398
chr5	60899104	60899333	E070	-30649
chr5	60899447	60899592	E070	-30390
chr5	60900512	60900748	E070	-29234
chr5	60901109	60901163	E070	-28819
chr5	60906442	60906495	E070	-23487
chr5	60906630	60906715	E070	-23267
chr5	60908461	60908595	E070	-21387
chr5	60908849	60908944	E070	-21038
chr5	60916538	60917006	E070	-12976
chr5	60917130	60917341	E070	-12641
chr5	60920582	60920642	E070	-9340
chr5	60927144	60927940	E070	-2042
chr5	60927979	60928178	E070	-1804
chr5	60949780	60949847	E070	19798
chr5	60950178	60950231	E070	20196
chr5	60952888	60952938	E070	22906
chr5	60952982	60953059	E070	23000
chr5	60953651	60953776	E070	23669
chr5	60953912	60953972	E070	23930
chr5	60970236	60970561	E070	40254
chr5	60970828	60970891	E070	40846
chr5	60970894	60971210	E070	40912
chr5	60971482	60971532	E070	41500
chr5	60881907	60881995	E071	-47987
chr5	60882143	60882367	E071	-47615
chr5	60882374	60882504	E071	-47478
chr5	60882646	60882741	E071	-47241
chr5	60883088	60883214	E071	-46768
chr5	60895344	60895582	E071	-34400
chr5	60895707	60896178	E071	-33804
chr5	60896323	60896389	E071	-33593
chr5	60899104	60899333	E071	-30649
chr5	60899447	60899592	E071	-30390
chr5	60900512	60900748	E071	-29234
chr5	60901109	60901163	E071	-28819
chr5	60901454	60901517	E071	-28465
chr5	60905534	60906170	E071	-23812
chr5	60908461	60908595	E071	-21387
chr5	60908849	60908944	E071	-21038
chr5	60910571	60910729	E071	-19253
chr5	60912971	60913142	E071	-16840
chr5	60913940	60914230	E071	-15752
chr5	60915208	60915406	E071	-14576
chr5	60916119	60916248	E071	-13734
chr5	60916538	60917006	E071	-12976
chr5	60917130	60917341	E071	-12641
chr5	60918100	60918304	E071	-11678
chr5	60919335	60919616	E071	-10366
chr5	60919662	60919761	E071	-10221
chr5	60920154	60920198	E071	-9784
chr5	60920582	60920642	E071	-9340
chr5	60926869	60926985	E071	-2997
chr5	60927979	60928178	E071	-1804
chr5	60928218	60928369	E071	-1613
chr5	60928477	60928822	E071	-1160
chr5	60928887	60929017	E071	-965
chr5	60931248	60931328	E071	1266
chr5	60932651	60932705	E071	2669
chr5	60935660	60935772	E071	5678
chr5	60936058	60936185	E071	6076
chr5	60936272	60936338	E071	6290
chr5	60936552	60936730	E071	6570
chr5	60937908	60937972	E071	7926
chr5	60938111	60938277	E071	8129
chr5	60946129	60946203	E071	16147
chr5	60952888	60952938	E071	22906
chr5	60952982	60953059	E071	23000
chr5	60953651	60953776	E071	23669
chr5	60953912	60953972	E071	23930
chr5	60954335	60955657	E071	24353
chr5	60955990	60956044	E071	26008
chr5	60956416	60956487	E071	26434
chr5	60962181	60962325	E071	32199
chr5	60963480	60963718	E071	33498
chr5	60963833	60963894	E071	33851
chr5	60968451	60968501	E071	38469
chr5	60968708	60969317	E071	38726
chr5	60969433	60969514	E071	39451
chr5	60969785	60969861	E071	39803
chr5	60970236	60970561	E071	40254
chr5	60970828	60970891	E071	40846
chr5	60970894	60971210	E071	40912
chr5	60883088	60883214	E072	-46768
chr5	60895344	60895582	E072	-34400
chr5	60895707	60896178	E072	-33804
chr5	60900512	60900748	E072	-29234
chr5	60901109	60901163	E072	-28819
chr5	60901454	60901517	E072	-28465
chr5	60901894	60901944	E072	-28038
chr5	60905534	60906170	E072	-23812
chr5	60908461	60908595	E072	-21387
chr5	60908849	60908944	E072	-21038
chr5	60910571	60910729	E072	-19253
chr5	60912971	60913142	E072	-16840
chr5	60913940	60914230	E072	-15752
chr5	60915208	60915406	E072	-14576
chr5	60916119	60916248	E072	-13734
chr5	60916538	60917006	E072	-12976
chr5	60917130	60917341	E072	-12641
chr5	60918100	60918304	E072	-11678
chr5	60919335	60919616	E072	-10366
chr5	60919662	60919761	E072	-10221
chr5	60920154	60920198	E072	-9784
chr5	60920582	60920642	E072	-9340
chr5	60926869	60926985	E072	-2997
chr5	60928218	60928369	E072	-1613
chr5	60928477	60928822	E072	-1160
chr5	60928887	60929017	E072	-965
chr5	60931248	60931328	E072	1266
chr5	60931933	60932043	E072	1951
chr5	60932651	60932705	E072	2669
chr5	60935660	60935772	E072	5678
chr5	60936058	60936185	E072	6076
chr5	60936272	60936338	E072	6290
chr5	60936552	60936730	E072	6570
chr5	60937908	60937972	E072	7926
chr5	60938111	60938277	E072	8129
chr5	60946129	60946203	E072	16147
chr5	60952888	60952938	E072	22906
chr5	60952982	60953059	E072	23000
chr5	60953651	60953776	E072	23669
chr5	60953912	60953972	E072	23930
chr5	60954335	60955657	E072	24353
chr5	60955990	60956044	E072	26008
chr5	60956416	60956487	E072	26434
chr5	60961931	60961981	E072	31949
chr5	60963480	60963718	E072	33498
chr5	60963833	60963894	E072	33851
chr5	60968708	60969317	E072	38726
chr5	60969433	60969514	E072	39451
chr5	60969785	60969861	E072	39803
chr5	60970236	60970561	E072	40254
chr5	60970828	60970891	E072	40846
chr5	60970894	60971210	E072	40912
chr5	60971482	60971532	E072	41500
chr5	60895344	60895582	E073	-34400
chr5	60895707	60896178	E073	-33804
chr5	60899447	60899592	E073	-30390
chr5	60900512	60900748	E073	-29234
chr5	60901109	60901163	E073	-28819
chr5	60901454	60901517	E073	-28465
chr5	60905534	60906170	E073	-23812
chr5	60908461	60908595	E073	-21387
chr5	60910571	60910729	E073	-19253
chr5	60912971	60913142	E073	-16840
chr5	60916119	60916248	E073	-13734
chr5	60916538	60917006	E073	-12976
chr5	60917130	60917341	E073	-12641
chr5	60918100	60918304	E073	-11678
chr5	60919335	60919616	E073	-10366
chr5	60919662	60919761	E073	-10221
chr5	60920154	60920198	E073	-9784
chr5	60920582	60920642	E073	-9340
chr5	60927979	60928178	E073	-1804
chr5	60931248	60931328	E073	1266
chr5	60931933	60932043	E073	1951
chr5	60932651	60932705	E073	2669
chr5	60933482	60933692	E073	3500
chr5	60936552	60936730	E073	6570
chr5	60938111	60938277	E073	8129
chr5	60946129	60946203	E073	16147
chr5	60954335	60955657	E073	24353
chr5	60962181	60962325	E073	32199
chr5	60971482	60971532	E073	41500
chr5	60881907	60881995	E074	-47987
chr5	60882143	60882367	E074	-47615
chr5	60882374	60882504	E074	-47478
chr5	60882646	60882741	E074	-47241
chr5	60894979	60895039	E074	-34943
chr5	60895047	60895087	E074	-34895
chr5	60895344	60895582	E074	-34400
chr5	60895707	60896178	E074	-33804
chr5	60896323	60896389	E074	-33593
chr5	60899104	60899333	E074	-30649
chr5	60899447	60899592	E074	-30390
chr5	60900512	60900748	E074	-29234
chr5	60901109	60901163	E074	-28819
chr5	60901454	60901517	E074	-28465
chr5	60905534	60906170	E074	-23812
chr5	60908461	60908595	E074	-21387
chr5	60908849	60908944	E074	-21038
chr5	60910571	60910729	E074	-19253
chr5	60912971	60913142	E074	-16840
chr5	60913940	60914230	E074	-15752
chr5	60915208	60915406	E074	-14576
chr5	60916119	60916248	E074	-13734
chr5	60916538	60917006	E074	-12976
chr5	60917130	60917341	E074	-12641
chr5	60918100	60918304	E074	-11678
chr5	60919335	60919616	E074	-10366
chr5	60919662	60919761	E074	-10221
chr5	60920154	60920198	E074	-9784
chr5	60926869	60926985	E074	-2997
chr5	60927144	60927940	E074	-2042
chr5	60927979	60928178	E074	-1804
chr5	60928218	60928369	E074	-1613
chr5	60928477	60928822	E074	-1160
chr5	60928887	60929017	E074	-965
chr5	60931248	60931328	E074	1266
chr5	60931933	60932043	E074	1951
chr5	60932651	60932705	E074	2669
chr5	60935660	60935772	E074	5678
chr5	60936058	60936185	E074	6076
chr5	60936272	60936338	E074	6290
chr5	60936552	60936730	E074	6570
chr5	60937908	60937972	E074	7926
chr5	60938111	60938277	E074	8129
chr5	60946129	60946203	E074	16147
chr5	60952888	60952938	E074	22906
chr5	60952982	60953059	E074	23000
chr5	60953651	60953776	E074	23669
chr5	60953912	60953972	E074	23930
chr5	60954335	60955657	E074	24353
chr5	60955990	60956044	E074	26008
chr5	60956416	60956487	E074	26434
chr5	60961931	60961981	E074	31949
chr5	60963480	60963718	E074	33498
chr5	60965462	60965614	E074	35480
chr5	60968708	60969317	E074	38726
chr5	60969433	60969514	E074	39451
chr5	60969785	60969861	E074	39803
chr5	60970236	60970561	E074	40254
chr5	60970828	60970891	E074	40846
chr5	60970894	60971210	E074	40912
chr5	60974923	60975068	E074	44941
chr5	60975143	60975203	E074	45161
chr5	60905534	60906170	E081	-23812
chr5	60906257	60906332	E081	-23650
chr5	60906442	60906495	E081	-23487
chr5	60906630	60906715	E081	-23267
chr5	60908461	60908595	E081	-21387
chr5	60908849	60908944	E081	-21038
chr5	60916119	60916248	E081	-13734
chr5	60916538	60917006	E081	-12976
chr5	60917130	60917341	E081	-12641
chr5	60927144	60927940	E081	-2042
chr5	60908461	60908595	E082	-21387
chr5	60916119	60916248	E082	-13734
chr5	60920582	60920642	E082	-9340
chr5	60920834	60920960	E082	-9022

Promoter Annotation (GRCh37.p13)

Chromosome	Start	End	Region	Distance(-/+:Up/Downstream)
chr5	60921381	60922446	E067	-7536
chr5	60922549	60922994	E067	-6988
chr5	60921381	60922446	E068	-7536
chr5	60922549	60922994	E068	-6988
chr5	60921381	60922446	E069	-7536
chr5	60922549	60922994	E069	-6988
chr5	60921381	60922446	E070	-7536
chr5	60921381	60922446	E071	-7536
chr5	60922549	60922994	E071	-6988
chr5	60921381	60922446	E072	-7536
chr5	60921381	60922446	E073	-7536
chr5	60921381	60922446	E074	-7536
chr5	60921381	60922446	E082	-7536